You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) Caspase 8 antibody for Immunohistochemistry

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Reactivity
Human, Mouse (Murine), Monkey, Rat (Rattus)
339
95
68
18
18
13
4
1
1
1
Host
Mouse
272
100
11
2
Clonality
Monoclonal
Conjugate
This Caspase 8 antibody is un-conjugated
17
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
323
112
80
70
42
33
31
24
12
11
8
5
2
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN969003
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.2290752 ABIN1532233 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.2290752 ABIN2705694 IHC WB Rabbit Center Log in to see Polyclonal
0.2290752 ABIN2163270 IHC ELISA WB Rabbit IgG Ser347 Log in to see Polyclonal
0.2290752 ABIN2163269 IHC ELISA WB Rabbit IgG Ser347 Log in to see Polyclonal
0.2290752 ABIN2470495 IP IHC WB Rabbit IgG Log in to see Polyclonal
0.2290752 ABIN1846137 FACS IHC ELISA WB Mouse IgG1 Log in to see
0.0011325823 ABIN2745526 ICC FACS IHC ELISA WB Rat IgG1 Log in to see 3B10
0.0011325823 ABIN2745525 FACS IHC ELISA WB Rat IgG1 Log in to see 1G12
0.0011325823 ABIN3183671 ELISA IHC WB Rabbit IgG Ser2 Log in to see Polyclonal
0.0011325823 ABIN408525 IHC (p) IHC WB Rabbit IgG Ser347 Log in to see Polyclonal
0.0011325823 ABIN1885811 IF IHC WB Rabbit AA 1-227 Log in to see Polyclonal
0.0011325823 ABIN1585723 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0011325823 ABIN2852721 IHC WB Rabbit Log in to see Polyclonal
0.0011325823 ABIN2618019 ICC FACS IHC ELISA WB Rat IgG1, kappa Log in to see 3B10
0.0011325823 ABIN2135496 IHC ELISA WB Rabbit IgG pSer347 Log in to see Polyclonal
0.0011325823 ABIN2852720 IHC WB Mouse Log in to see
0.0011325823 ABIN3188046 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN1846133 IHC WB Rabbit Log in to see Polyclonal
0.0011325823 ABIN1173797 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN3181527 IHC WB Mouse Log in to see

Top referenced anti-Caspase 8 antibody for Immunohistochemistry

Similar anti-Caspase 8 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 15 Antibodies 30 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 4 Antibodies 8 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 11 Antibodies
Immunofluorescence (IF) 5 Antibodies 5 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 29 Antibodies 31 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 55 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Reactivity Human, Mouse (Murine), Monkey, Rat (Rattus)
(339), (95), (68), (18), (18), (13), (4), (1), (1), (1)
Host Mouse
(272), (100), (11), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 8 antibody is un-conjugated
(17), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(323), (112), (80), (70), (42), (33), (31), (24), (12), (11), (8), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN969003) Images
Purification Ascites
Immunogen Purified recombinant fragment of human CASP8 expressed in E. coli.
Clone 1H11
Isotype IgG1

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling References for anti-Caspase 8 Antibody (ABIN969003) Images back to top
Antigen
Alternative Name CASP8 (CASP8 Antibody Abstract)
Background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.
Molecular Weight 26 kDa
Gene ID 841
HGNC 841
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling References for anti-Caspase 8 Antibody (ABIN969003) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details References for anti-Caspase 8 Antibody (ABIN969003) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-Caspase 8 Antibody (ABIN969003)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Fulda: "Caspase-8 in cancer biology and therapy." in: Cancer letters, Vol. 281, Issue 2, pp. 128-33, 2009

Jani, Gobejishvili, Hote, Barve, Joshi-Barve, Kharebava, Suttles, Chen, McClain, Barve: "Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells." in: Cell research, Vol. 19, Issue 3, pp. 358-69, 2009

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN969003) back to top
Supplier Images
ELISA image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN969003) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN969003) Figure 2: Flow cytometric analysis of NIH/3T3 cells using CASP8 mouse mAb (blue) and ...
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN969003) Figure 3: Immunohistochemical analysis of paraffin-embedded colon cancer tissues usin...
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN969003) Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues usin...
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN969003) Figure 5: Western blot analysis using CASP8 mouse mAb against Hela (1), Jurkat (2), T...