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anti-Human CD11b antibody for Blocking Reagent

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Reactivity
Human
671
499
208
80
31
22
17
15
13
11
9
9
9
8
6
4
4
4
2
Host
Mouse
491
397
161
17
4
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is conjugated to PE
167
127
93
51
16
15
15
15
14
13
11
11
9
9
9
6
6
6
6
5
5
5
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
857
246
221
172
162
139
97
95
89
67
26
21
20
19
13
8
6
5
5
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2662970
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1177001 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN2662971 BR FACS IP IHC WB PE Mouse IgG1 kappa Log in to see ICRF44 7
1 ABIN2688906 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN490173 BR FACS Func IHC (fro) IP Neut Rat IgG2b Log in to see M1-70
1 ABIN1822246 BR FACS IP Mouse IgG1, kappa Log in to see CBRM1-5
1 ABIN1959978 BR FACS Func ICC IHC (fro) IP Neut Mouse IgG1 Log in to see ICRF44
1 ABIN206917 BR FACS Func Neut Mouse IgG1 Log in to see MEM-170
1 ABIN2742255 BR ELISA FACS Func IF IHC (fro) IP Rat IgG2b, kappa Log in to see M1-70
1 ABIN1967141 BR FACS Func ICC IHC (fro) IP Neut Mouse IgG1 Log in to see ICRF44
1 ABIN1956007 BR FACS Biotin Mouse IgG1 Log in to see hCD11b
1 ABIN1957240 BR FACS FITC Mouse IgG1 Log in to see hCD11b
1 ABIN225690 BR FACS IHC (fro) IP Rat IgG2b Log in to see M1-70
1 ABIN3024273 BR FACS IF Rat IgG2b, kappa Log in to see M1-70
1 ABIN1967096 BR FACS Mouse IgG1 Log in to see hCD11b
1 ABIN2688907 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70
1 ABIN3024274 BR FACS IF Rat IgG2b, kappa Log in to see M1-70

Top referenced anti-CD11b antibody for Blocking Reagent

Similar anti-CD11b Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 3 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 17 Antibodies
Cytometry by Time of Flight (CyTOF) 6 Antibodies
ELISA 78 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 518 Antibodies
Functional Studies (Func) 61 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 82 Antibodies
Immunofluorescence (IF) 122 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 120 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 118 Antibodies

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Human
(671), (499), (208), (80), (31), (22), (17), (15), (13), (11), (9), (9), (9), (8), (6), (4), (4), (4), (2)
Host Mouse
(491), (397), (161), (17), (4), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is conjugated to PE
(167), (127), (93), (51), (16), (15), (15), (15), (14), (13), (11), (11), (9), (9), (9), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(857), (246), (221), (172), (162), (139), (97), (95), (89), (67), (26), (21), (20), (19), (13), (8), (6), (5), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2662970) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Marmoset, Pig (Porcine)
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone ICRF44
Isotype IgG1 kappa

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b Antibody (ABIN2662970) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, Activation of Innate immune Response

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b Antibody (ABIN2662970) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b Antibody (ABIN2662970) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD11b Antibody (ABIN2662970)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Charles, Hardwick, Daugas, Illei, Rivera: "Basophils and the T helper 2 environment can promote the development of lupus nephritis." in: Nature medicine, Vol. 16, Issue 6, pp. 701-7, 2010

David, Kacher, Specks, Aviram: "Interaction of proteinase 3 with CD11b/CD18 (beta2 integrin) on the cell membrane of human neutrophils." in: Journal of leukocyte biology, Vol. 74, Issue 4, pp. 551-7, 2003

Marsik, Halama, Cardona, Wlassits, Mayr, Pleiner, Jilma: "Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans." in: Shock (Augusta, Ga.), Vol. 20, Issue 6, pp. 493-6, 2003

Jadhav, Bochner, Konstantopoulos: "Hydrodynamic shear regulates the kinetics and receptor specificity of polymorphonuclear leukocyte-colon carcinoma cell adhesive interactions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5986-93, 2001

Rezzonico, Imbert, Chicheportiche, Dayer et al.: "Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a ..." in: Blood, Vol. 97, Issue 10, pp. 2932-40, 2001

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Stewart, Thiel, Hogg: "Leukocyte integrins." in: Current opinion in cell biology, Vol. 7, Issue 5, pp. 690-6, 1996

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2662970) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD11b antibody (Integrin alpha M)  (PE) (ABIN2662970) anti-Integrin alpha M (ITGAM) antibody (PE)