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anti-Human CD11b antibody for Blocking Reagent

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • C3bi
  • CD11B
  • Cd11b
  • CD11b/CD18
  • CR3
  • CR3A
  • F730045J24Rik
  • Ly-40
  • MAC-1
  • Mac-1
  • Mac-1a
  • MAC1
  • MAC1A
  • MO1A
  • SLEB6
Reactivity
Human
615
467
146
67
26
20
17
17
17
11
10
9
5
4
3
2
2
1
Host
Mouse
476
413
117
17
4
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is conjugated to PE
164
122
88
51
18
17
12
12
11
11
11
10
10
9
7
6
5
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
799
243
206
162
139
112
78
77
72
69
19
14
11
7
6
5
4
3
3
3
3
3
2
1
1
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2662970
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008709465 ABIN1177001 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
0.0008709465 ABIN2662971 BR FACS IP IHC WB PE Mouse IgG1 kappa Log in to see ICRF44 7
0.0008709465 ABIN2688906 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
0.0008709465 ABIN1822246 BR FACS IP Mouse IgG1, kappa Log in to see CBRM1-5
0.0008709465 ABIN1957240 BR FACS FITC Mouse IgG1 Log in to see hCD11b
0.0008709465 ABIN1956007 BR FACS Biotin Mouse IgG1 Log in to see hCD11b
0.0008709465 ABIN3024273 BR FACS IF Rat IgG2b, kappa Log in to see M1-70
0.0008709465 ABIN1967096 BR FACS Mouse IgG1 Log in to see hCD11b
0.0008709465 ABIN2688907 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70
0.0008709465 ABIN3024274 BR FACS IF Rat IgG2b, kappa Log in to see M1-70

Top referenced anti-CD11b antibody for Blocking Reagent

Similar anti-CD11b Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 3 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 11 Antibodies
ELISA 62 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 446 Antibodies
Functional Studies (Func) 60 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 60 Antibodies
Immunofluorescence (IF) 92 Antibodies
Immunohistochemistry (IHC) 121 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 95 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 57 Antibodies
Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) 2 Antibodies

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Human
(615), (467), (146), (67), (26), (20), (17), (17), (17), (11), (10), (9), (5), (4), (3), (2), (2), (1)
Host Mouse
(476), (413), (117), (17), (4), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is conjugated to PE
(164), (122), (88), (51), (18), (17), (12), (12), (11), (11), (11), (10), (10), (9), (7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(799), (243), (206), (162), (139), (112), (78), (77), (72), (69), (19), (14), (11), (7), (6), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2662970) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Marmoset, Pig (Porcine)
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone ICRF44
Isotype IgG1 kappa

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b Antibody (ABIN2662970) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b Antibody (ABIN2662970) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b Antibody (ABIN2662970) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD11b Antibody (ABIN2662970)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Charles, Hardwick, Daugas, Illei, Rivera: "Basophils and the T helper 2 environment can promote the development of lupus nephritis." in: Nature medicine, Vol. 16, Issue 6, pp. 701-7, 2010

David, Kacher, Specks, Aviram: "Interaction of proteinase 3 with CD11b/CD18 (beta2 integrin) on the cell membrane of human neutrophils." in: Journal of leukocyte biology, Vol. 74, Issue 4, pp. 551-7, 2003

Marsik, Halama, Cardona, Wlassits, Mayr, Pleiner, Jilma: "Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans." in: Shock (Augusta, Ga.), Vol. 20, Issue 6, pp. 493-6, 2003

Jadhav, Bochner, Konstantopoulos: "Hydrodynamic shear regulates the kinetics and receptor specificity of polymorphonuclear leukocyte-colon carcinoma cell adhesive interactions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5986-93, 2001

Rezzonico, Imbert, Chicheportiche, Dayer et al.: "Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a ..." in: Blood, Vol. 97, Issue 10, pp. 2932-40, 2001

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Stewart, Thiel, Hogg: "Leukocyte integrins." in: Current opinion in cell biology, Vol. 7, Issue 5, pp. 690-6, 1996

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2662970) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD11b antibody (Integrin alpha M)  (PE) (ABIN2662970) anti-Integrin alpha M (ITGAM) antibody (PE)