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anti-Human CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Epitope
AA 256-286, N-Term
52
24
19
18
16
16
13
8
6
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
648
492
202
65
26
20
10
9
9
8
8
5
4
3
2
2
2
1
1
Host
Rabbit
493
398
160
18
4
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
167
128
94
51
16
15
15
15
14
13
11
11
9
9
6
6
6
6
6
5
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
852
239
211
169
148
148
100
97
86
71
26
19
17
13
8
6
5
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN951175
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.096462 ABIN730918 FACS IF (p) IHC (p) WB Rabbit IgG AA 50-100 Log in to see Polyclonal 7
12.096462 ABIN741285 FACS IF (p) IHC (p) WB Rabbit IgG AA 520-570 Log in to see Polyclonal 4
12.096462 ABIN4289475 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN118146 FACS IHC (fro) IF IHC (p) IP WB Rat IgG2b Log in to see M1-70-15 18
1 ABIN374760 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal 1
1 ABIN782999 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal 1
1 ABIN654625 FACS IHC (p) WB Rabbit Ig AA 253-282, N-Term Log in to see Polyclonal 1
1 ABIN409930 FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 23
1 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 16
1 ABIN118145 FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70 14
1 ABIN319553 Func FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15 6
1 ABIN3043258 IHC (p) WB Rabbit IgG AA 17-382 Log in to see Polyclonal
1 ABIN4289448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rabbit AA 250-350, Internal Region Log in to see Polyclonal 1
1 ABIN4289454 IHC IHC (p) WB Mouse IgG1 Log in to see CL1719
1 ABIN1177001 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN1724066 IHC (fro) FACS IHC (p) IP Rat IgG2b Log in to see M1-70-15
1 ABIN951176 IF IHC (p) Chicken Ig Log in to see Polyclonal
1 ABIN1732807 ICC FACS IF IHC (p) WB Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN1732800 FACS ICC IF IHC (p) WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal
1 ABIN4289459 FACS ICC IF IHC (fro) IHC (p) Alexa Fluor 488 Rat IgG2b Log in to see M1-70-15

Top referenced anti-CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-CD11b Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 3 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 11 Antibodies
Cytometry by Time of Flight (CyTOF) 6 Antibodies
ELISA 75 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 492 Antibodies
Functional Studies (Func) 61 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 90 Antibodies
Immunofluorescence (IF) 123 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 116 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 106 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antibodies

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 256-286, N-Term
(52), (24), (19), (18), (16), (16), (13), (8), (6), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(648), (492), (202), (65), (26), (20), (10), (9), (9), (8), (8), (5), (4), (3), (2), (2), (2), (1), (1)
Host Rabbit
(493), (398), (160), (18), (4), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(167), (128), (94), (51), (16), (15), (15), (15), (14), (13), (11), (11), (9), (9), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(852), (239), (211), (169), (148), (148), (100), (97), (86), (71), (26), (19), (17), (13), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN951175) Images
Specificity This antibody reacts to CD11b.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the N-terminal region of human CD11b
Isotype Ig

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b Antibody (ABIN951175) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
Molecular Weight 127179 Da
Gene ID 3684
NCBI Accession NP_000623
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b Antibody (ABIN951175) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b Antibody (ABIN951175) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CD11b Antibody (ABIN951175)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Gjelstrup, Boesen, Kragstrup, Jørgensen, Klein, Thiel, Deleuran, Vorup-Jensen: "Shedding of large functionally active CD11/CD18 Integrin complexes from leukocyte membranes during synovial inflammation distinguishes three types of arthritis through differential epitope exposure." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 4154-68, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN951175) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD11b antibody (Integrin alpha M) (AA 256-286) (ABIN951175) CD11b Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogr...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CD11b antibody (Integrin alpha M) (AA 256-286) (ABIN951175) CD11b antibody (N-term) immunohistochemistry analysis in formalin fixed and par...
Western Blotting (WB) image for anti-CD11b antibody (Integrin alpha M) (AA 256-286) (ABIN951175) CD11b Antibody (N-term) western blot analysis in A549,K562 cell line lysates (3...