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anti-Mouse (Murine) CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Epitope
AA 50-100
49
24
21
19
15
15
15
13
8
6
6
5
5
5
4
4
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
683
470
191
78
31
19
17
15
13
11
9
9
7
7
5
4
4
4
2
2
Host
Rabbit
489
368
161
16
5
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
147
119
88
48
19
19
15
14
14
14
13
11
10
9
9
9
8
8
7
7
6
6
6
6
5
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
833
234
228
172
164
139
96
94
92
67
24
21
21
13
8
6
5
5
4
3
3
1
1
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN730918
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN118146 FACS IHC (fro) IF IHC (p) IP WB Rat IgG2b Log in to see M1-70-15 18
1 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 16
1 ABIN409930 FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 23
1 ABIN118145 FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70 14
1 ABIN3043258 IHC (p) WB Rabbit IgG AA 17-382 Log in to see Polyclonal
1 ABIN319553 Func FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15 6
1 ABIN4289448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rabbit AA 250-350, Internal Region Log in to see Polyclonal 1
1 ABIN573960 IHC (fro) FACS IHC (p) IP Rat IgG2b Log in to see M1-70-15
1 ABIN1177001 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN951176 IF IHC (p) Chicken Ig Log in to see Polyclonal
1 ABIN1732800 FACS ICC IF IHC (p) WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal
1 ABIN439874 FACS ICC IHC IHC (fro) IHC (p) IP in vitro FITC Rat IgG2b kappa Log in to see M1-70
1 ABIN1724066 IHC (fro) FACS IHC (p) IP Rat IgG2b Log in to see M1-70-15
1 ABIN4289459 FACS ICC IF IHC (fro) IHC (p) Alexa Fluor 488 Rat IgG2b Log in to see M1-70-15
1 ABIN135135 FACS IHC (p) IP IHC Rat IgG2b Log in to see M1-70 4
1 ABIN2688906 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN1732807 ICC FACS IF IHC (p) WB Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN2478234 Func IHC (fro) FACS IF IHC (p) IP Rat IgG2b Log in to see M1-70-15 4
1 ABIN730927 IHC (p) WB HRP Rabbit IgG AA 50-100 Log in to see Polyclonal
1 ABIN741294 IHC (p) WB HRP Rabbit IgG AA 520-570 Log in to see Polyclonal

Top referenced anti-CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-CD11b Antibodies

Application / Reactivity Rat (Rattus)
Agonist (Agon) 1 Antibodies
Blocking Reagent (BR) 4 Antibodies
ELISA 15 Antibodies
Flow Cytometry (FACS) 138 Antibodies
Functional Studies (Func) 4 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 26 Antibodies
Immunofluorescence (IF) 31 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 25 Antibodies
Immunohistochemistry (IHC) 49 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 43 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 37 Antibodies
Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)) 1 Antibodies
Immunoprecipitation (IP) 33 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 50-100
(49), (24), (21), (19), (15), (15), (15), (13), (8), (6), (6), (5), (5), (5), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(683), (470), (191), (78), (31), (19), (17), (15), (13), (11), (9), (9), (7), (7), (5), (4), (4), (4), (2), (2)
Host Rabbit
(489), (368), (161), (16), (5), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(147), (119), (88), (48), (19), (19), (15), (14), (14), (14), (13), (11), (10), (9), (9), (9), (8), (8), (7), (7), (6), (6), (6), (6), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(833), (234), (228), (172), (164), (139), (96), (94), (92), (67), (24), (21), (21), (13), (8), (6), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 8 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN730918) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CD11b
Isotype IgG

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b Antibody (ABIN730918) Images back to top
Antigen
Alternative Name CD11b/c (ITGAM Antibody Abstract)
Background

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Subcellular location: Extracellular


Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, ITGAM
Gene ID 3684
UniProt P11215
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b Antibody (ABIN730918) Images back to top
Application Notes WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b Antibody (ABIN730918) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-CD11b Antibody (ABIN730918)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Product cited in:

Yamaguchi, Sato, Kato-Itoh, Goto, Hara, Sanbo, Mizuno, Kobayashi, Yanagida, Umino, Ota, Hamanaka, Masaki, Rashid, Hirabayashi, Nakauchi: "Interspecies organogenesis generates autologous functional islets." in: Nature, Vol. 542, Issue 7640, pp. 191-196, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).

Velázquez, Enos, McClellan, Cranford, Chatzistamou, Singh, Nagarkatti, Nagarkatti, Fan, Murphy: "MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 6, pp. G347-58, 2016

Kobayashi, Tanizaki, Kimura, Ishida, Nosaka, Toujima, Kuninaka, Minami, Ino, Kondo: "AG490, a Jak2 inhibitor, suppressed the progression of murine ovarian cancer." in: European journal of pharmacology, Vol. 766, pp. 63-75, 2015

Zhang, Hu, Liu, Ye, Gui, Zhou, Qi, He, Wang, Wang: "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." in: Scientific reports, Vol. 5, pp. 15948, 2015

Liu, Xie, Ma, Zhang, Liang, Shi, Yu, Feng, Zhang, Wu: "Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation." in: Scientific reports, Vol. 4, pp. 4833, 2014

Yu, Yang, Wang, Chen, Lu, Luo, Wang: "Ethanol supports macrophage recruitment and reinforces invasion and migration of lewis lung carcinoma." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 10, pp. 2597-606, 2014

Long, Qiu, Wang, Yang, Jia, Xin, Wang, Han, Fei, Liu: "Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy." in: Brain research, Vol. 1532, pp. 1-13, 2013

Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: "Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells." in: Neuroscience, Vol. 212, pp. 214-24, 2012

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN730918) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-CD11b antibody (Integrin alpha M) (AA 50-100) (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CD11b antibody (Integrin alpha M) (AA 50-100) (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Flow Cytometry (FACS) image for anti-CD11b antibody (Integrin alpha M) (AA 50-100) (ABIN730918) Human U937 cells probed with CD11b/c Polyclonal Antibody, Unconjugated ) (0.2ug) for...
Western Blotting (WB) image for anti-CD11b antibody (Integrin alpha M) (AA 50-100) (ABIN730918) This image was kindly submitted by Kandy Velazquez from USC School of Medicine. Mouse...