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anti-Human CFLAR antibody for Enzyme Immunoassay

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • 2310024N18Rik
  • A430105C05Rik
  • c-Flip
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • CASH
  • Cash
  • CASP8AP1
  • Casper
  • cflar
  • CFLAR
  • CLARP
  • Clarp1
  • ENSMUSG00000072980
  • FLAME
  • FLAME-1
  • FLAME1
  • Flip
  • FLIP
  • Gm9845
  • I-FLICE
  • MRIT
Epitope
AA 152-182, Middle Region
37
21
19
13
13
13
10
8
7
6
6
6
6
5
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
199
79
57
2
2
2
2
2
1
Host
Rabbit
155
60
4
Clonality
Polyclonal
Conjugate
This CFLAR antibody is un-conjugated
7
4
3
2
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
179
73
48
36
33
23
22
15
12
7
3
3
1
1
1
Supplier
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Catalog No. ABIN951489
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008833851 ABIN336100 EIA WB Mouse IgG3 AA 1-376, N-Term Log in to see 5D8 2
0.0008833851 ABIN499846 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 4
0.0008833851 ABIN499850 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 4
0.0008833851 ABIN499848 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 4
0.0008833851 ABIN781988 EIA IF IHC (p) WB Mouse IgG2a Log in to see 2F12
0.0008833851 ABIN615235 EIA IF IHC (p) WB Rabbit AA 191-209 Log in to see Polyclonal

Top referenced anti-CFLAR antibody for Enzyme Immunoassay

Similar anti-CFLAR Antibodies

Application / Reactivity Human
ELISA 66 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 13 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 30 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 48 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 33 Antibodies
Immunoprecipitation (IP) 15 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
SDS-PAGE (SDS) 1 Antibodies
Western Blotting (WB) 168 Antibodies

General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope AA 152-182, Middle Region
(37), (21), (19), (13), (13), (13), (10), (8), (7), (6), (6), (6), (6), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(199), (79), (57), (2), (2), (2), (2), (2), (1)
Host Rabbit
(155), (60), (4)
Clonality
Polyclonal
Conjugate This CFLAR antibody is un-conjugated
(7), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(179), (73), (48), (36), (33), (23), (22), (15), (12), (7), (3), (3), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN951489) Images
Specificity This antibody reacts to CFLAR.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Immunogen KLH conjugated synthetic peptide between 152~182 amino acids from the Center region of human CFLAR
Isotype Ig

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling References for anti-CFLAR Antibody (ABIN951489) Images back to top
Antigen
Alternative Name CFLAR / Casper / I-FLICE (CFLAR Antibody Abstract)
Background Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Molecular Weight 55344 Da
Gene ID 8837
NCBI Accession NP_001120655
Pathways Apoptosis

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling References for anti-CFLAR Antibody (ABIN951489) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details References for anti-CFLAR Antibody (ABIN951489) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CFLAR Antibody (ABIN951489)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Kim, Pettingell, Jung, Kovacs, Tanzi: "Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease." in: Science (New York, N.Y.), Vol. 277, Issue 5324, pp. 373-6, 1998

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN951489) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) CFLAR Antibody (Center) flow cytometric analysis of k562 cells (bottom histogram) com...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CFLAR Antibod...
Western Blotting (WB) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) Western blot analysis of CFLAR Antibody (Center) in HepG2 cell line lysates (35µg/lan...