anti-Human CFLAR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • Clarp1
  • cflar
  • CFLAR
  • FLIP
  • CASH
  • CASP8AP1
  • CLARP
  • Casper
  • FLAME
  • FLAME-1
  • FLAME1
  • I-FLICE
  • MRIT
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • 2310024N18Rik
  • A430105C05Rik
  • Cash
  • ENSMUSG00000072980
  • Flip
  • Gm9845
  • c-Flip
  • CASP8 and FADD-like apoptosis regulator a
  • CASP8 and FADD-like apoptosis regulator
  • cellular FLICE-like inhibitory protein
  • cflara
  • CFLAR
  • cflar
  • Cflar
  • C-FLIP
Epitope
C-Term, long form
41
36
24
23
17
16
15
14
10
7
6
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
280
135
89
6
2
2
1
1
Host
Rabbit
161
112
23
Clonality
Polyclonal
Conjugate
This CFLAR antibody is un-conjugated
11
8
7
6
6
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
257
121
103
42
39
30
29
26
21
8
4
2
2
1
1
1
1
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Catalog No. ABIN1106673
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.588177 ABIN951489 EIA FACS IHC (p) WB Rabbit Ig AA 152-182, Middle Region Log in to see Polyclonal 1
13.588177 ABIN4312114 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
13.588177 ABIN725255 IF (p) IHC (p) WB Rabbit IgG AA 1-50 Log in to see Polyclonal
13.588177 ABIN737946 IF (p) IHC (p) WB Rabbit IgG AA 462-480 Log in to see Polyclonal
13.588177 ABIN298166 IHC (p) WB Rabbit IgG AA 206-222 Log in to see Polyclonal
13.588177 ABIN4312116 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
13.588177 ABIN461877 ICC IHC (p) ELISA WB Rabbit AA 191-209 Log in to see Polyclonal
13.588177 ABIN615235 EIA IF IHC (p) WB Rabbit AA 191-209 Log in to see Polyclonal
13.588177 ABIN4312107 IHC IHC (p) Rabbit Log in to see Polyclonal
1 ABIN653068 FACS IHC (p) WB Rabbit Ig AA 145-174, Center Log in to see Polyclonal 1
1 ABIN4312113 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 9
1 ABIN372409 IHC (p) WB Rabbit IgG AA 206-222 Log in to see Polyclonal
1 ABIN272307 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN781988 EIA IF IHC (p) WB Mouse IgG2a Log in to see 2F12
1 ABIN957199 IHC (fro) IHC (p) IP WB Rabbit AA 75-92 Log in to see Polyclonal
1 ABIN725264 IHC (p) WB HRP Rabbit IgG AA 1-50 Log in to see Polyclonal
1 ABIN737955 IHC (p) WB HRP Rabbit IgG AA 462-480 Log in to see Polyclonal
1 ABIN768891 IF IHC (p) ELISA WB Mouse IgG2a, kappa AA 178-277 Log in to see 2F12
1 ABIN1492934 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN725257 IHC (p) WB Biotin Rabbit IgG AA 1-50 Log in to see Polyclonal

General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope C-Term, long form
(41), (36), (24), (23), (17), (16), (15), (14), (10), (7), (6), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(280), (135), (89), (6), (2), (2), (1), (1)
Host Rabbit
(161), (112), (23)
Clonality
Polyclonal
Conjugate This CFLAR antibody is un-conjugated
(11), (8), (7), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(257), (121), (103), (42), (39), (30), (29), (26), (21), (8), (4), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling References for anti-CFLAR antibody (ABIN1106673) Images
Specificity Recognizes FLIP-L No cross reactivity with other proteins.
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide corresponding to a sequence mapping at the C-terminal of Human FLIP- L, identical to the related Mouse sequence.
Isotype IgG

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling References for anti-CFLAR antibody (ABIN1106673) Images back to top
Antigen
Alternative Name CFLAR / Casper / I-FLICE (CFLAR Antibody Abstract)
Background Irmler et al. (1997) isolated human cDNAs encoding 2 isoforms of FLIP. FLIP(L), the longer isoform, contains 2 DEDs and a caspase-like domain, and FLIP(S), the shorter isoform, contains only the 2 DEDs followed by a C-terminal extension of approximately 50 amino acids. High levels of FLIP(L) protein were detected in melanoma cell lines and malignant melanoma tumors. FLIP may be implicated in tissue homeostasis as an important regulator of apoptosis.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Gene ID 8837
NCBI Accession NP_001120655
UniProt O15519
Pathways Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling References for anti-CFLAR antibody (ABIN1106673) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details References for anti-CFLAR antibody (ABIN1106673) Images back to top
Reconstitution Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
Concentration 0.5 mg/mL
Buffer 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CFLAR antibody (ABIN1106673)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Irmler, Thome, Hahne, Schneider, Hofmann, Steiner, Bodmer, Schröter, Burns, Mattmann, Rimoldi, French, Tschopp: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling References for anti-CFLAR antibody (ABIN1106673) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (C-Term), (long form) antibody (ABIN1106673) Immunohistochemical FLIPL antibody staining of Human Mammary Cancer Paraffin Sections.