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anti-Human CFLAR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • Clarp1
  • cflar
  • CFLAR
  • FLIP
  • CASH
  • CASP8AP1
  • CLARP
  • Casper
  • FLAME
  • FLAME-1
  • FLAME1
  • I-FLICE
  • MRIT
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • 2310024N18Rik
  • A430105C05Rik
  • Cash
  • ENSMUSG00000072980
  • Flip
  • Gm9845
  • c-Flip
  • CASP8 and FADD-like apoptosis regulator a
  • CASP8 and FADD-like apoptosis regulator
  • cellular FLICE-like inhibitory protein
  • cflara
  • CFLAR
  • cflar
  • Cflar
  • C-FLIP
Epitope
AA 152-182, Middle Region
43
25
21
17
15
15
13
10
10
7
6
6
5
5
4
4
4
2
2
2
2
2
2
2
2
2
1
1
1
Reactivity
Human
258
111
84
2
2
2
2
Host
Rabbit
169
84
23
Clonality
Polyclonal
Conjugate
This CFLAR antibody is un-conjugated
9
6
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
232
96
76
43
39
30
26
20
14
7
4
2
1
1
1
1
1
Supplier
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Catalog No. ABIN951489
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.096846 ABIN1106673 IHC (p) WB Rabbit IgG C-Term, long form Log in to see Polyclonal 1
12.096846 ABIN4312114 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
12.096846 ABIN298166 IHC (p) WB Rabbit IgG AA 206-222 Log in to see Polyclonal
12.096846 ABIN4312116 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
12.096846 ABIN461877 ICC IHC (p) ELISA WB Rabbit AA 191-209 Log in to see Polyclonal
12.096846 ABIN725255 IF (p) IHC (p) WB Rabbit IgG AA 1-50 Log in to see Polyclonal
12.096846 ABIN615235 EIA IF IHC (p) WB Rabbit AA 191-209 Log in to see Polyclonal
12.096846 ABIN737946 IF (p) IHC (p) WB Rabbit IgG AA 462-480 Log in to see Polyclonal
12.096846 ABIN4312107 IHC IHC (p) Rabbit Log in to see Polyclonal
1 ABIN653068 FACS IHC (p) WB Rabbit Ig AA 145-174, Center Log in to see Polyclonal 1
1 ABIN401040 IHC (p) WB Rabbit IgG Log in to see Polyclonal 4
1 ABIN4312113 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 9
1 ABIN372409 IHC (p) WB Rabbit IgG AA 206-222 Log in to see Polyclonal
1 ABIN272307 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN781988 EIA IF IHC (p) WB Mouse IgG2a Log in to see 2F12
1 ABIN957199 IHC (fro) IHC (p) IP WB Rabbit AA 75-92 Log in to see Polyclonal
1 ABIN609612 IHC (p) WB Rabbit IgG AA 456-471 Log in to see Polyclonal
1 ABIN1492934 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4312112 ELISA FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1733024 IHC (p) WB Rabbit IgG AA 206-222 Log in to see Polyclonal

Top referenced anti-CFLAR antibody for Immunohistochemistry (Paraffin-embedded Sections)

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Application / Reactivity Human
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Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 15 Antibodies
Immunochromatography (IC) 2 Antibodies
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Immunofluorescence (IF) 29 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
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General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope AA 152-182, Middle Region
(43), (25), (21), (17), (15), (15), (13), (10), (10), (7), (6), (6), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity Human
(258), (111), (84), (2), (2), (2), (2)
Host Rabbit
(169), (84), (23)
Clonality
Polyclonal
Conjugate This CFLAR antibody is un-conjugated
(9), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(232), (96), (76), (43), (39), (30), (26), (20), (14), (7), (4), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN951489) Images
Specificity This antibody reacts to CFLAR.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Immunogen KLH conjugated synthetic peptide between 152~182 amino acids from the Center region of human CFLAR
Isotype Ig

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling References for anti-CFLAR Antibody (ABIN951489) Images back to top
Antigen
Alternative Name CFLAR / Casper / I-FLICE (CFLAR Antibody Abstract)
Background Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Molecular Weight 55344 Da
Gene ID 8837
NCBI Accession NP_001120655
Pathways Apoptosis

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling References for anti-CFLAR Antibody (ABIN951489) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details References for anti-CFLAR Antibody (ABIN951489) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CFLAR Antibody (ABIN951489)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Kim, Pettingell, Jung, Kovacs, Tanzi: "Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease." in: Science (New York, N.Y.), Vol. 277, Issue 5324, pp. 373-6, 1998

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN951489) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) CFLAR Antibody (Center) flow cytometric analysis of k562 cells (bottom histogram) com...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CFLAR Antibod...
Western Blotting (WB) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 152-182) (ABIN951489) Western blot analysis of CFLAR Antibody (Center) in HepG2 cell line lysates (35µg/lan...