anti-Rat (Rattus) Clusterin antibody for Enzyme Immunoassay

Recommended Clusterin Antibody (supplied by: Log in to see )

Antigen
Clusterin (CLU) Antibodies
  • LOC100136120
  • clu
  • MGC53055
  • zgc:73352
  • xclu
  • MGC89163
  • CLU
  • APO-J
  • APOJ
  • CLI
  • CLU1
  • CLU2
  • KUB1
  • NA1/NA2
  • SGP-2
  • SGP2
  • SP-40
  • TRPM-2
  • TRPM2
  • DAG
  • RATTRPM2B
  • SP40
  • TRPM2B
  • Trpm2
  • Trpmb
  • AI893575
  • ApoJ
  • Cli
  • D14Ucla3
  • Sgp-2
  • Sgp2
  • Sugp-2
  • GP80
  • gpIII
  • 40
  • clusterin-1
  • clusterin
  • Clusterin
  • LOC100136120
  • clu
  • CLU
  • clus
  • Clu
Epitope
C-Term
41
28
20
18
15
14
12
12
11
11
10
9
9
6
5
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
305
63
60
18
17
5
3
3
3
2
1
1
1
Host
Goat
174
138
77
8
5
2
Clonality
Polyclonal
Conjugate
This Clusterin antibody is un-conjugated
33
27
12
12
8
7
4
3
3
3
3
3
3
3
3
3
3
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
355
274
160
107
60
55
32
29
29
15
12
7
2
1
Supplier
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Catalog No. ABIN5553549
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN950468 EIA WB Goat Internal Region, AA 312-325 Log in to see Polyclonal

General

Antigen Clusterin (CLU) Antibodies
Epitope C-Term
(41), (28), (20), (18), (15), (14), (12), (12), (11), (11), (10), (9), (9), (6), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(305), (63), (60), (18), (17), (5), (3), (3), (3), (2), (1), (1), (1)
Host Goat
(174), (138), (77), (8), (5), (2)
Clonality
Polyclonal
Conjugate This Clusterin antibody is un-conjugated
(33), (27), (12), (12), (8), (7), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(355), (274), (160), (107), (60), (55), (32), (29), (29), (15), (12), (7), (2), (1)
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Product Details anti-Clusterin Antibody

Target Details Clusterin Application Details Handling Images
Sequence C-EKALQEYRRK SRAE
Specificity This antibody recognizes Clusterin / ApoJ (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Mouse, Rat.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen Peptide with sequence from the C Terminus of the protein sequence according to NP_038520.1. Genename: Clu

Target Details Clusterin

Product Details anti-Clusterin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Apolipoprotein J (Apo J) (CLU Antibody Abstract)
Background At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individual's relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Apolipoprotein J is the major secreted product of Sertoli cells and is thought to play a critical role in spermatogenesis. The protein was shown to be a normal constituent of human blood and is also thought to be a control mechanism of the complement cascade. It prevents the binding of a C5b-C7 complex to the membrane of the target cell and in this way inhibits complement-mediated cytolysis. Apolipoprotein J is overexpressed in human prostate and breast cancers and in squamous cell carcinomas. Suppression of Apolipoprotein J renders these cells sensitive to chemotherapeutic drug-mediated apoptosis. It has been proposed that elevated levels of Apolipoprotein J may promote oncogenic transformation and tumor progression by interfering with BAX proapoptotic activities.Synonyms: 40, 40, AAG4, APOJ, Aging-associated gene 4 protein, CLI, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-40, KUB1, Ku70-binding protein 1, NA1/NA2, SP-40, Testosterone-repressed prostate message 2
Gene ID 12759, 10090
UniProt Q06890
Research Area Metabolism, Receptors
Pathways Apoptosis, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-Clusterin Antibody Target Details Clusterin Handling Images back to top
Application Notes Peptide ELISA: 1/8000. Western Blot: 0.3-1 μg/mL. Approx.37 kDa band observed in Mouse Brain and Testis lysatesand in Rat Brain and Ovary lysates (calculated MW of 51.7 kDa according to Mouse
Restrictions For Research Use only

Handling

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.