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anti-Human CRADD antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CRADD Antibody (supplied by: Log in to see )

Antigen
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) Antibodies
  • cradd
  • CRADD
  • DKFZp468A2219
  • LOC100226369
  • MGC78788
  • MGC89035
  • MRT34
  • RAIDD
  • raidd
  • zgc:101717
Epitope
C-Term
19
12
11
11
8
8
6
3
3
2
2
1
1
1
Reactivity
Human
127
16
15
2
2
1
1
1
1
Host
Rabbit
108
18
2
1
Clonality
Polyclonal
Conjugate
This CRADD antibody is un-conjugated
8
8
6
3
3
3
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
114
54
27
16
11
10
9
2
2
1
1
Supplier
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Catalog No. ABIN500563
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.32227957 ABIN213922 ICC IHC (p) WB Rabbit AA 99-117 Log in to see Polyclonal
0.32227957 ABIN615297 IHC (p) WB Rabbit Log in to see Polyclonal
0.00090133876 ABIN302805 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00090133876 ABIN3201804 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 1-199 Log in to see
0.00090133876 ABIN462424 IHC (p) WB Rabbit Log in to see Polyclonal
0.00090133876 ABIN1733289 ICC IHC (p) WB Rabbit IgG AA 99-117 Log in to see Polyclonal
0.00090133876 ABIN1733288 IHC (p) WB Rabbit IgG AA 112-126 Log in to see Polyclonal
0.00090133876 ABIN715166 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00090133876 ABIN1077905 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 1-199 Log in to see Polyclonal
0.00090133876 ABIN2768543 IHC (p) IHC WB Rabbit AA 99-117 Log in to see Polyclonal
0.00090133876 ABIN2764676 IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-CRADD antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-CRADD Antibodies

Application / Reactivity Human
ELISA 54 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 17 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 27 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Western Blotting (WB) 114 Antibodies

General

Antigen CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) Antibodies
Epitope C-Term
(19), (12), (11), (11), (8), (8), (6), (3), (3), (2), (2), (1), (1), (1)
Reactivity Human
(127), (16), (15), (2), (2), (1), (1), (1), (1)
Host Rabbit
(108), (18), (2), (1)
Clonality
Polyclonal
Conjugate This CRADD antibody is un-conjugated
(8), (8), (6), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(114), (54), (27), (16), (11), (10), (9), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-CRADD Antibody

Target Details CRADD Application Details Handling References for anti-CRADD Antibody (ABIN500563) Images
Specificity This antibody detects RAIDD at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Peptide affinity chromatography
Immunogen RAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD.
Isotype IgG

Target Details CRADD

Product Details anti-CRADD Antibody Application Details Handling References for anti-CRADD Antibody (ABIN500563) Images back to top
Antigen
Alternative Name RAIDD (CRADD Antibody Abstract)
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.Synonyms: CRADD, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, RIP-associated protein with a death domain
Gene ID 8738
UniProt P78560
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-CRADD Antibody Target Details CRADD Handling References for anti-CRADD Antibody (ABIN500563) Images back to top
Application Notes ELISA. Western blot: 1: 500 - 1: 1000, a 22 kDa band should be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CRADD Antibody Target Details CRADD Application Details References for anti-CRADD Antibody (ABIN500563) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-CRADD Antibody (ABIN500563)

Product Details anti-CRADD Antibody Target Details CRADD Application Details Handling Images back to top
Background publications

Hofmann, Bucher, Tschopp: "The CARD domain: a new apoptotic signalling motif." in: Trends in biochemical sciences, Vol. 22, Issue 5, pp. 155-6, 1997

Duan, Dixit: "RAIDD is a new 'death' adaptor molecule." in: Nature, Vol. 385, Issue 6611, pp. 86-9, 1997

Ahmad, Srinivasula, Wang, Talanian, Litwack, Fernandes-Alnemri, Alnemri: "CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP." in: Cancer research, Vol. 57, Issue 4, pp. 615-9, 1997

Images

Product Details anti-CRADD Antibody Target Details CRADD Application Details Handling References for anti-CRADD Antibody (ABIN500563) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CRADD antibody (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain) (C-Term) (ABIN500563) Immunohistochemistry of RAIDD in human kidney tissue with this product at 10 μg/ml.
Western Blotting (WB) image for anti-CRADD antibody (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain) (C-Term) (ABIN500563) Western blot analysis of RAIDD in HeLa total cell lysate with this product at 1 μg/ml.