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anti-Human CYLD antibody for Flow Cytometry

Recommended CYLD Antibody (supplied by: Log in to see )

Antigen
Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antibodies
  • cyld
  • 2010013M14Rik
  • 2900009M21Rik
  • C130039D01Rik
  • CDMT
  • CYLD1
  • EAC
  • mKIAA0849
  • LRRGT00003
  • Rp1
  • Rp1h
  • BRSS
  • CYLDI
  • MFT
  • MFT1
  • SBS
  • TEM
  • USPL2
  • cylindromatosis (turban tumor syndrome)
  • cylindromatosis (turban tumor syndrome), a
  • ubiquitin carboxyl-terminal hydrolase CYLD
  • CYLD
  • cylda
  • LOC100362727
  • Cyld
Epitope
AA 305-582
17
15
10
7
5
3
3
3
2
2
2
1
1
1
Reactivity
Human
57
53
33
7
4
3
3
3
2
2
1
1
1
Host
Mouse
48
19
9
Clonality
Monoclonal
Conjugate
This CYLD antibody is un-conjugated
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
49
24
14
14
13
11
10
2
1
1
Options
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Available images

Catalog No. ABIN4908488
$ 291.50
Plus shipping costs $45.00

Similar anti-CYLD Antibodies

Application / Reactivity Human
ELISA 15 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 11 Antibodies
Immunofluorescence (IF) 14 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antibodies
Immunohistochemistry (IHC) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Simple Western (SimWes) 2 Antibodies
Western Blotting (WB) 33 Antibodies

General

Antigen Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antibodies
Epitope AA 305-582
(17), (15), (10), (7), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Reactivity Human
(57), (53), (33), (7), (4), (3), (3), (3), (2), (2), (1), (1), (1)
Host Mouse
(48), (19), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CYLD antibody is un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Western Blotting (WB)
(49), (24), (14), (14), (13), (11), (10), (2), (1), (1)
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Product Details anti-CYLD Antibody

Target Details CYLD Application Details Handling Images
Immunogen This CYLD antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 305-582 amino acids from human CYLD.
Clone 1667CT857-3-6-1
Isotype IgG2a kappa

Target Details CYLD

Product Details anti-CYLD Antibody Application Details Handling Images back to top
Antigen
Alternative Name CYLD (CYLD Antibody Abstract)
Background

Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Has endodeubiquitinase activity. Plays an important role in the regulation of pathways leading to NF-kappa-B activation (PubMed:12917689, PubMed:12917691). Contributes to the regulation of cell survival, proliferation and differentiation via its effects on NF-kappa-B activation (PubMed:12917690). Negative regulator of Wnt signaling (PubMed:20227366). Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules (PubMed:19893491). Plays a role in the regulation of microtubule dynamics, and thereby contributes to the regulation of cell proliferation, cell polarization, cell migration, and angiogenesis (PubMed:18222923, PubMed:20194890). Required for normal cell cycle progress and normal cytokinesis (PubMed:17495026, PubMed:19893491). Inhibits nuclear translocation of NF-kappa-B. Plays a role in the regulation of inflammation and the innate immune response, via its effects on NF-kappa-B activation (PubMed:18636086). Dispensable for the maturation of intrathymic natural killer cells, but required for the continued survival of immature natural killer cells. Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity). Involved in the regulation of ciliogenesis, allowing ciliary basal bodies to migrate and dock to the plasma membrane, this process does not depend on NF-kappa-B activation (By similarity).


Synonyms: EAC, MFT, SBS, TEM, BRSS, CDMT, MFT1, CYLD1, CYLDI, USPL2, Ubiquitin carboxyl-terminal hydrolase CYLD, Deubiquitinating enzyme CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, CYLD, KIAA0849, HSPC057
Gene ID 1540
UniProt Q9NQC7
Research Area Proteolysis / Ubiquitin
Pathways Apoptosis, Activation of Innate immune Response

Application Details

Product Details anti-CYLD Antibody Target Details CYLD Handling Images back to top
Application Notes FC (1:25) WB(1:4000)
Restrictions For Research Use only

Handling

Product Details anti-CYLD Antibody Target Details CYLD Application Details Images back to top
Storage -20 °C
Storage Comment Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-CYLD Antibody Target Details CYLD Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-CYLD antibody (Cylindromatosis (Turban Tumor Syndrome)) (AA 305-582) (ABIN4908488) Lane 1: HeLa Cell lysates, probed with CYLD (1667CT857.3.6.1) Monoclonal Antibody, un...