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anti-Human CYLD antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended CYLD Antibody (supplied by: Log in to see )

Antigen
Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antibodies
  • 2010013M14Rik
  • 2900009M21Rik
  • BRSS
  • C130039D01Rik
  • CDMT
  • cyld
  • CYLD1
  • CYLDI
  • EAC
  • LRRGT00003
  • MFT
  • MFT1
  • mKIAA0849
  • Rp1
  • Rp1h
  • SBS
  • TEM
  • USPL2
Epitope
AA 390-440, pSer418
14
12
11
6
5
3
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
51
45
28
5
3
2
1
1
1
1
1
Host
Rabbit
41
19
9
Clonality
Polyclonal
Conjugate
This CYLD antibody is un-conjugated
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
47
24
14
12
11
9
9
1
1
1
1
Supplier
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Supplier Product No.
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Catalog No. ABIN683833
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN876074 IF (p) Alexa Fluor 350 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN876076 IF (p) Alexa Fluor 647 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN876078 IF (p) Alexa Fluor 488 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN876075 IF (p) Alexa Fluor 555 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN683836 IF (p) Cy3 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN683837 IF (p) Cy5 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN683838 IF (p) Cy5.5 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN683839 IF (p) Cy7 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN683840 IF (p) FITC Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN2812134 IF (p) Alexa Fluor 594 Rabbit IgG AA 390-440, pSer418 Log in to see Polyclonal
0.0008846439 ABIN750158 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-CYLD Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 9 Antibodies 14 Antibodies 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 7 Antibodies 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 9 Antibodies
Western Blotting (WB) 18 Antibodies 34 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 4 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antibodies
Epitope AA 390-440, pSer418
(14), (12), (11), (6), (5), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(51), (45), (28), (5), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(41), (19), (9)
Clonality
Polyclonal
Conjugate This CYLD antibody is un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(47), (24), (14), (12), (11), (9), (9), (1), (1), (1), (1)
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Product Details anti-CYLD Antibody

Target Details CYLD Application Details Handling Images
Specificity This phophorylation site is homologous to that of Ser414 in Mouse and Ser415 in Rat.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human CYLD around the phosphorylation site of Ser418
Isotype IgG

Target Details CYLD

Product Details anti-CYLD Antibody Application Details Handling Images back to top
Antigen
Alternative Name Cyld (CYLD Antibody Abstract)
Background

Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Has endodeubiquitinase activity. Plays an important role in the regulation of pathways leading to NF-kappa-B activation. Contributes to the regulation of cell survival, proliferation and differentiation via its effects on NF-kappa-B activation. Negative regulator of Wnt signaling. Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules. Plays a role in the regulation of microtubule dynamics, and thereby contributes to the regulation of cell proliferation, cell polarization, cell migration, and angiogenesis. Required for normal cell cycle progress and normal cytokinesis. Inhibits nuclear translocation of NF-kappa-B. Plays a role in the regulation of inflammation and the innate immune response, via its effects on NF-kappa-B activation. Dispensable for the maturation of intrathymic natural killer cells, but required for the continued survival of immature natural killer cells. Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity).

Subcellular location: Cytoplasm, Cell membrane


Synonyms: EAC, MFT, SBS, TEM, BRSS, CDMT, MFT1, CYLD1, CYLDI, USPL2, Ubiquitin carboxyl-terminal hydrolase CYLD, Deubiquitinating enzyme CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, CYLD, KIAA0849, HSPC057
Gene ID 1540
UniProt Q9NQC7
Research Area Proteolysis / Ubiquitin
Pathways Apoptosis

Application Details

Product Details anti-CYLD Antibody Target Details CYLD Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-CYLD Antibody Target Details CYLD Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-CYLD Antibody Target Details CYLD Application Details Handling back to top
Supplier Images
ELISA image for anti-CYLD antibody (Cylindromatosis (Turban Tumor Syndrome)) (AA 390-440) (ABIN683833) Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16...
SDS-PAGE (SDS) image for anti-CYLD antibody (Cylindromatosis (Turban Tumor Syndrome)) (AA 390-440) (ABIN683833) Lane 1: rat brain lysates Lane 2: human gastric carcinoma lysates probed with Anti ph...