Browse our anti-Cytochrome C (CYCS) Antibodies

Full name:
anti-Cytochrome C, Somatic Antibodies (CYCS)
On are 418 Cytochrome C, Somatic (CYCS) Antibodies from 33 different suppliers available. Additionally we are shipping Cytochrome C Proteins (89) and Cytochrome C Kits (67) and many more products for this protein. A total of 590 Cytochrome C products are currently listed.
bln, bs30f07.y1, CG13263, CG17903, CYC, cycs, CYCSA, cyct, cyt-c-d, cyt-c-p, Cyt-c1, cyt-c2, cyt.c, cytc, cyt c, CytC-1, CytC-2, Cytc-d, cyt c-d, cyt c-p, Cytc-p, CytC1, cytochrome c, dc3, dc4, DMc01, Dmel\\CG13263, Dmel\\CG17903, ENSMUSG00000058927, HCS, ms(2)04445, pDMc01, pDMc02, THC4, wu:fk52b01, zgc:86706
list all antibodies Gene Name GeneID UniProt
CYCS 54205 P99999
Anti-Rat CYCS CYCS 25309 P62898
CYCS 13063 P62897

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All available anti-Cytochrome C Antibodies

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Top referenced anti-Cytochrome C Antibodies

  1. Dog (Canine) Monoclonal Cytochrome C Primary Antibody for ICC, FACS - ABIN252468 : Eid, Lewis, Kumar: Mifepristone pretreatment overcomes resistance of prostate cancer cells to tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL). in Molecular cancer therapeutics 2002 (PubMed)
    Show all 44 references for 252468

  2. Dog (Canine) Monoclonal Cytochrome C Primary Antibody for IHC (fro), IHC - ABIN251788 : Pervaiz, Seyed, Hirpara, Clément, Loh: Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cells. in Blood 1999 (PubMed)
    Show all 32 references for 251788

  3. Human Polyclonal Cytochrome C Primary Antibody for IF (cc), IF (p) - ABIN723590 : Wang, Wang, Shan, Song, Dai, Wang, Chi: Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. in Brain research bulletin 2008 (PubMed)
    Show all 14 references for 723590

  4. Chicken Polyclonal Cytochrome C Primary Antibody for IP, WB - ABIN222880 : Kuhn, Chen, Voorhees, Strader, Shenk, Sun, Demo, Bennett, van Leeuwen, Chanan-Khan, Orlowski: Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. in Blood 2007 (PubMed)
    Show all 10 references for 222880

  5. Human Polyclonal Cytochrome C Primary Antibody for ICC, IHC (p) - ABIN3042783 : Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014 (PubMed)
    Show all 10 references for 3042783

  6. Rat (Rattus) Polyclonal Cytochrome C Primary Antibody for WB - ABIN223076 : Machiya, Shibata, Yamauchi, Hirama, Wada, Inoue, Abe, Takabatake, Sata, Kubota: Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure. in American journal of respiratory cell and molecular biology 2007 (PubMed)
    Show all 8 references for 223076

  7. Cow (Bovine) Polyclonal Cytochrome C Primary Antibody for WB - ABIN223077 : Zhao, Chen, Lu, Dong, Wang, Bi, Wu, Guo, Wu, Guo: TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma. in Cancer research 2008 (PubMed)
    Show all 4 references for 223077

  8. Human Monoclonal Cytochrome C Primary Antibody for IP, WB - ABIN967529 : Goshorn, Retzel, Jemmerson: Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c. in The Journal of biological chemistry 1991 (PubMed)
    Show all 3 references for 967529

  9. Human Monoclonal Cytochrome C Primary Antibody for IF (p), IHC (p) - ABIN5000922 : Ding, Chen, Wu, Chen, Zhang, Fan, Wang, Ji, Xie, Ning, Shen: Increased expression of HERPUD1 involves in neuronal apoptosis after intracerebral hemorrhage. in Brain research bulletin 2016 (PubMed)

More Antibodies against Cytochrome C Interaction Partners

Fruit Fly (Drosophila melanogaster) Cytochrome C, Somatic (CYCS) interaction partners

  1. results reveal Blanks to be a unique component of a nuclear siRNA/dsRNA-binding complex that contributes to essential RNA silencing-related pathways in the male germ line

  2. We further identified loss-of-function mutations in one of the two Drosophila cyt-c genes, cyt-c-d, which block caspase (show CASP3 Antibodies) activation and subsequent spermatid terminal differentiation.

  3. DARK-mediated DRONC activation occurs independently of Cyt-c-p

  4. We found that cyt c-d--as with ark (show APAF1 Antibodies) and dronc-regulates scutellar bristle number, which is known to depend on caspase (show CASP3 Antibodies) activity. Collectively, our results indicate a role of Cyt c in caspase (show CASP3 Antibodies) regulation of Drosophila somatic cells.

Human Cytochrome C, Somatic (CYCS) interaction partners

  1. Data suggest that although HCCS (show HCCS Antibodies) mediates heme attachment to N-terminal cysteine in heme-attachment site (CXXXH) of cytochrome C variants, up to 50% of cytochrome C produced is modified in an oxygen-dependent manner, resulting in a mixed population of cytochrome c. [HCCS (show HCCS Antibodies) = holocytochrome c synthase (show HCCS Antibodies)]

  2. Data suggest that the stronger effect of K72A mutation on the peroxidase activity of human versus yeast cytochrome c results from relief of steric interactions between side chains at positions 72 and 81 (Ile in human vs Ala in yeast), which suppresses the dynamics of omega-loop D necessary for the intrinsic peroxidase activity of cytochrome c.

  3. These findings establish a framework for understanding the molecular basis of cytochrome c-mediated blocking of SET/TAF-Ibeta.

  4. Monitoring of serum cytochrome c might also serve as a sensitive apoptotic marker in vivo reflecting chemotherapy-induced cell death burden in patients with non-small cell lung cancer.

  5. G-Rh2 (show RHAG Antibodies) causes rapid and dramatic translocation of both Bak (show BAK1 Antibodies) and Bax (show BAX Antibodies), which subsequently triggers mitochondrial cytochrome c release and consequent caspase (show CASP3 Antibodies) activation.

  6. The mitochondrial metalloprotease (show ADAM8 Antibodies) OMA1 (show OMA1 Antibodies) was activated in a Bax (show BAX Antibodies)- and Bak (show BAK1 Antibodies)-dependent fashion.

  7. In vitro ultrastructural changes of MCF-7 for metastasise bone cancer and induction of apoptosis via mitochondrial cytochrome C released by CaCO3/Dox nanocrystals

  8. a mechanism of multiple radical formations in the cytochrome c-phospholipid complexes under H2O2 treatment, consistent with the stabilization of the radical in the G41S mutant, which elicits a greater peroxidase activity from cytochrome c

  9. Data indicate a novel missense mutation (Y48H) of the cytochrome c (CYCS) gene responsible for thrombocytopenia.

  10. results suggest the impact of residue 41 on the conformation of cytochrome c influences its ability to act in both of its physiological roles, electron transport and caspase (show CASP3 Antibodies) activation

Horse (Equine) Cytochrome C, Somatic (CYCS) interaction partners

  1. Cytochrome c undergoes large structural fluctuations, using the interacting regions with cytochrome c oxidase as a fulcrum.

  2. Data suggest that ferric forms of variants of cytochrome c (wild type, T49V mutation, and Y67R/M80A mutations) are Lysine-ligated at neutral pH; hydrogen-bonding network appears to be important in controlling ligation of the native Met80 to the heme iron.

  3. analysis of CO photo-dissociation from chloramine-T modified horse heart cytochrome-c

  4. The effect of pH on thermodynamic stability and folding kinetics of horse cytochrome c has been described.

  5. The cardiolipin binding and the peroxidase activity of cytochrome c depend on conformational heterogeneity and oligomerization.

  6. The data suggest a two-step process of thermal unfolding of cytochrome c for all protonation states.

  7. The study shows that cardiolipin modulates allosterically the nitrite reductase activity of horse heart cytochrome c.

  8. Horse Cc binds CcP (show CRYGD Antibodies) but forms a much more dynamic complex. A single conservative mutation of Lys (show LYZ Antibodies)-13 to ARG reduces the dynamics and enhances the specificity. The K13A mutation of Cc increases the dynamic nature of the complex with CcP (show CRYGD Antibodies).

  9. X-ray crystallographic evidence for functional models of horse cytochrome c.

  10. The fluorescence Stokes shift response in Zn-cytochrome c includes a significant contribution from the surrounding hydration shell, which assumes a perturbed hydrogen-bonding network owing to the binding of guanidinium(+) ions to the protein surface.

Cow (Bovine) Cytochrome C, Somatic (CYCS) interaction partners

  1. Data using ribose 5-P suggest that glycation of cyt c (at lysines in ATP binding site) results in cyto c being less able to transfer electrons to cytochrome oxidase and in reduced affinity of cyt c for cardiolipin-containing liposomes.

  2. The presence of structural collective motions on a picosecond timescale for the heme protein, cytochrome c, as a function of oxidation and hydration, was investigated.

  3. peroxidase activity shown by cardiolipin-bound cytochrome c is indicative of a less packed protein tertiary conformation in the complex

Pig (Porcine) Cytochrome C, Somatic (CYCS) interaction partners

  1. Results suggest that excess or restricted protein supply during pregnancy alters expression of CYCS and leads to hypomethylation of CpG sites in promoter in liver of offspring. (5' flanking region: amino acid sequence; nucleic acid sequence homology)

  2. Tissue expression profile analysis revealed that swine CYCS gene was highly expressed in muscle, fat and lung, moderately expressed in ovary, kidney, and liver, and weekly expressed in heart, spleen and small intestine.

Mouse (Murine) Cytochrome C, Somatic (CYCS) interaction partners

  1. the amount of cytochrome c in lymphomyeloid cells does not affect their development and normal functioning

  2. Abeta (show APP Antibodies) oligomers bind to BAK (show BAK1 Antibodies) on the membrane and induce apoptotic BAK (show BAK1 Antibodies) pores and cytochrome c release

  3. Data suggest that peroxidase activation of cytochrome c may induce apoptosis and contribute to anti-cancer properties of alpha-tocopherol succinate.

  4. Data indicate that mitochondrial alpha 7 nicotinic acetylcholine receptors (alpha7 nAChRs) regulate cytochrome c (cyt c) release by engaging intramitochondrial protein kinases.

  5. Data indicate that Y48H missense mutation of cytochrome c (CYCS) gene is associated with respiratory reduction and increased apoptosis in fibroblast.

  6. Translocation of a Bak (show BAK1 Antibodies) C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak (show BAK1 Antibodies) and Bax (show BAX Antibodies) apoptotic function.

  7. mitochondrial import and direct electron transfer from cytochrome c to Rac1 modulates mitochondrial H(2)O(2) production in alveolar macrophages pulmonary fibrosis.

  8. Fluoride exposure significantly elevated the protein expressions of cytochrome c and active caspase-3 (show CASP3 Antibodies).

  9. Resveratrol induces p53 (show TP53 Antibodies)-independent, X-linked inhibitor of apoptosis protein (XIAP (show XIAP Antibodies))-mediated Bax (show BAX Antibodies) protein oligomerization on mitochondria to initiate cytochrome c release and caspase (show CASP3 Antibodies) activation.

  10. High concentration glucose administration caused significantly increased expression of NF-kappaB (show NFKB1 Antibodies), Bax (show BAX Antibodies) and cytochrome C.

Cytochrome C (CYCS) Antigen Profile

Antigen Summary

This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Alternative names and synonyms associated with Cytochrome C (CYCS)

  • cytochrome c, somatic (cycs) antibody
  • cytochrome c, somatic (CYCS) antibody
  • cytochrome c, testis (cyct) antibody
  • Cytochrome c distal (Cyt-c-d) antibody
  • Cytochrome c proximal (Cyt-c-p) antibody
  • cytochrome c-like (LOC100724240) antibody
  • cytochrome c-like (CYC) antibody
  • cytochrome c, somatic (Cycs) antibody
  • cytochrome c, somatic b (cycsb) antibody
  • predicted gene 10053 (Gm10053) antibody
  • bln antibody
  • bs30f07.y1 antibody
  • CG13263 antibody
  • CG17903 antibody
  • CYC antibody
  • cycs antibody
  • CYCSA antibody
  • cyct antibody
  • cyt-c-d antibody
  • cyt-c-p antibody
  • Cyt-c1 antibody
  • cyt-c2 antibody
  • cyt.c antibody
  • cytc antibody
  • cyt c antibody
  • CytC-1 antibody
  • CytC-2 antibody
  • Cytc-d antibody
  • cyt c-d antibody
  • cyt c-p antibody
  • Cytc-p antibody
  • CytC1 antibody
  • cytochrome c antibody
  • dc3 antibody
  • dc4 antibody
  • DMc01 antibody
  • Dmel\\CG13263 antibody
  • Dmel\\CG17903 antibody
  • ENSMUSG00000058927 antibody
  • HCS antibody
  • ms(2)04445 antibody
  • pDMc01 antibody
  • pDMc02 antibody
  • THC4 antibody
  • wu:fk52b01 antibody
  • zgc:86706 antibody

Protein level used designations for CYCS

cytochrome c, testis-specific , cytochrome c, testis , cytochrome c, somatic , cytochrome c , CG13263-PA , CG13263-PB , Cyt-c-d-PA , Cyt-c-d-PB , blanks , cytochrome c distal , cytochrome-c-d , CG17903-PA , Cyt-c-p-PA , Cytochrome-c-proximal , cytochrome c DC4 , cytochrome c proximal , cytochrome-c-p , Cytochrome c , Cytochrome C, expressed in somatic tissues , somatic cytochrome c , fk52b01

444530 Xenopus laevis
394490 Xenopus (Silurana) tropicalis
100233210 Taeniopygia guttata
493538 Xenopus (Silurana) tropicalis
100171479 Pongo abelii
703093 Macaca mulatta
34995 Drosophila melanogaster
34996 Drosophila melanogaster
100724240 Cavia porcellus
100549365 Meleagris gallopavo
54205 Homo sapiens
475258 Canis lupus familiaris
100053958 Equus caballus
510767 Bos taurus
100170131 Sus scrofa
25309 Rattus norvegicus
13063 Mus musculus
420624 Gallus gallus
744779 Pan troglodytes
415158 Danio rerio
672195 Mus musculus
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