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anti-Human Cytochrome C antibody for Immunocytochemistry

Recommended Cytochrome C Antibody (supplied by: Log in to see )

Antigen
Cytochrome C, Somatic (CYCS) Antibodies
  • bln
  • bs30f07.y1
  • CG13263
  • CG17903
  • CYC
  • cyc
  • CYCS
  • cycs
  • CYCSA
  • cyct
  • cyt-c-d
  • cyt-c-p
  • Cyt-c1
  • cyt-c2
  • Cyt-c2
  • cyt.c
  • Cyt C
  • Cyt c
  • cyt c
  • Cytc
  • cytc
  • CytC-1
  • CytC-2
  • Cytc-d
  • cyt c-d
  • Cytc-p
  • cyt c-p
  • CytC1
  • cytochrome c
  • DC3
  • dc3
  • dc4
  • DC4
  • DMc01
  • Dmel\\CG13263
  • Dmel\\CG17903
  • ENSMUSG00000058927
  • hcs
  • HCS
  • ms(2)04445
  • pDMc01
  • pDMc02
  • THC4
  • wu:fk52b01
  • zgc:86706
Reactivity
Dog (Canine), Fruit Fly (Drosophila melanogaster), Horse (Equine), Human, Mammalian, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
309
232
175
95
63
57
29
28
28
26
24
20
16
8
7
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
Host
Mouse
238
139
7
2
Clonality
Monoclonal
Conjugate
This Cytochrome C antibody is un-conjugated
21
14
10
7
7
6
6
5
5
5
5
5
5
5
5
5
5
5
2
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
280
157
139
83
69
67
48
34
20
11
11
8
6
6
5
4
4
4
3
3
2
1
1
1
1
1
1
1
1
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Catalog No. ABIN252468
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009992593 ABIN1077973 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 5-100 Log in to see Polyclonal 1
0.0009992593 ABIN3042783 ICC IHC (p) WB Rabbit IgG AA 2-105 Log in to see Polyclonal
0.0009992593 ABIN3043697 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 91-105, C-Term Log in to see Polyclonal
0.0009992593 ABIN1493494 ICC IHC (fro) IHC (p) WB Rabbit AA 91-105 Log in to see Polyclonal
0.0009992593 ABIN2506675 ICC IF IHC (p) ELISA Rabbit IgG Log in to see Polyclonal
0.0009992593 ABIN1723142 ICC IHC (p) WB Mouse IgG2b Log in to see 7H8-2C12
0.0009992593 ABIN2740259 ICC IHC (p) WB Rabbit IgG AA 2-105 Log in to see Polyclonal
0.0009992593 ABIN2740262 ICC Rabbit IgG AA 91-105 Log in to see Polyclonal
0.0009992593 ABIN1724341 FACS ICC IHC (p) WB Mouse IgG2a Log in to see 7H8-2C12
0.0009992593 ABIN2740260 ICC Rabbit IgG Log in to see Polyclonal
0.0009992593 ABIN4301945 FACS ICC IF IHC IHC (p) WB Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301954 FACS ICC IF IHC IHC (p) WB Allophycocyanin Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301955 FACS ICC IF IHC IHC (p) WB DyLight 650 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301956 FACS ICC IF IHC IHC (p) WB DyLight 680 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301957 FACS ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301960 FACS ICC IF IHC IHC (p) WB PerCP Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301959 FACS ICC IF IHC IHC (p) WB DyLight 755 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301963 FACS ICC IF IHC IHC (p) WB DyLight 350 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301962 FACS ICC IF IHC IHC (p) WB DyLight 550 Mouse IgG2b kappa Log in to see 7H8-2C12
0.0009992593 ABIN4301961 FACS ICC IF IHC IHC (p) WB PE Mouse IgG2b kappa Log in to see 7H8-2C12

Top referenced anti-Cytochrome C antibody for Immunocytochemistry

Similar anti-Cytochrome C Antibodies

Application / Reactivity Dog (Canine) Horse (Equine) Human Mammalian Mouse (Murine) Rabbit Rat (Rattus) Pig (Porcine) Fruit Fly (Drosophila melanogaster)
Western Blotting (WB) 57 Antibodies 81 Antibodies 220 Antibodies 21 Antibodies 118 Antibodies 27 Antibodies 170 Antibodies 26 Antibodies 54 Antibodies
Radioimmunoassay (RIA) 3 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Neutralization (Neut) 8 Antibodies 7 Antibodies 7 Antibodies
Intracellular Staining (ICS) 4 Antibodies 2 Antibodies 2 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen Cytochrome C, Somatic (CYCS) Antibodies
Reactivity Dog (Canine), Fruit Fly (Drosophila melanogaster), Horse (Equine), Human, Mammalian, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(309), (232), (175), (95), (63), (57), (29), (28), (28), (26), (24), (20), (16), (8), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(238), (139), (7), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cytochrome C antibody is un-conjugated
(21), (14), (10), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(280), (157), (139), (83), (69), (67), (48), (34), (20), (11), (11), (8), (6), (6), (5), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-Cytochrome C Antibody

Target Details Cytochrome C Application Details Handling References for anti-Cytochrome C Antibody (ABIN252468) Images
Specificity An approx. 15 kDa band is observed. This antibody recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Purification Protein G purified
Immunogen Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon CYT were used as the immunogen (Jemmerson et al. 1991). The antibody recognizes an epitope within amino acids 93-104 of pigeon cytochrome C based on competitive ELISA results (Jemmerson et al. 1991).
Clone 7H8-2C12
Isotype IgG2b kappa

Target Details Cytochrome C

Product Details anti-Cytochrome C Antibody Application Details Handling References for anti-Cytochrome C Antibody (ABIN252468) Images back to top
Antigen
Alternative Name Cytochrome C (CYCS Antibody Abstract)
Background Gene Symbol: CYCS
Gene ID 54205, 13063, 25309
UniProt P99999
Research Area Metabolism, Apoptosis/Necrosis, Cancer
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Handling References for anti-Cytochrome C Antibody (ABIN252468) Images back to top
Application Notes Western Blot 0.05-0.5 μg/mL, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details References for anti-Cytochrome C Antibody (ABIN252468) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.5 % BSA
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References for anti-Cytochrome C Antibody (ABIN252468)

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling Images back to top
Product cited in:

Huang, Huang, Gou, Wang, Liao, Wang: "Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action." in: Bioconjugate chemistry, Vol. 27, Issue 9, pp. 2132-48, 2016 (Sample species: Human). Further details: Western Blotting

Patel, Garikapati, Ramaiah, Polavarapu, Bhadra, Bhadra: "miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1." in: Life sciences, Vol. 164, pp. 60-70, 2016 (Sample species: Human). Further details: Western Blotting

Waghela, Sharma, Dhumale, Pandey, Pathak: "Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells." in: PLoS ONE, Vol. 10, Issue 2, pp. e0117526, 2015 (Sample species: Human). Further details: Western Blotting

Dhumale, Waghela, Pathak: "Quercetin protects necrotic insult and promotes apoptosis by attenuating the expression of RAGE and its ligand HMGB1 in human breast adenocarcinoma cells." in: IUBMB life, Vol. 67, Issue 5, pp. 361-73, 2015 (Sample species: Human). Further details: Western Blotting

Pradhan, Pratheek, Garai, Kumar, Meena, Ghosh, Singh, Kumari, Chandrashekar, Goswami, Chattopadhyay, Kar, Maiti: "Induction of apoptosis by Fe(salen)Cl through caspase-dependent pathway specifically in tumor cells." in: Cell biology international, Vol. 38, Issue 10, pp. 1118-31, 2014 Further details: Western Blotting

Wang, Schilling, Niesman, Headrick, Finley, Kwan, Patel, Head, Roth, Yue, Patel: "Cardioprotective trafficking of caveolin to mitochondria is Gi-protein dependent." in: Anesthesiology, Vol. 121, Issue 3, pp. 538-48, 2014 (Sample species: Mouse (Murine)). Further details: Western Blotting

Nogami, Takahama, Okushima, Oyoshi, Fujimoto, Inouye: "Tailor-made designer helical peptides that induce mitochondrion-mediated cell death without necrosis." in: Chembiochem : a European journal of chemical biology, Vol. 15, Issue 17, pp. 2571-6, 2014 (Sample species: Human). Further details: Western Blotting

Kumar, Rao, Pal, Pal: "Hyperglycemia-induced oxidative stress induces apoptosis by inhibiting PI3-kinase/Akt and ERK1/2 MAPK mediated signaling pathway causing downregulation of 8-oxoG-DNA glycosylase levels in glial cells." in: The international journal of biochemistry & cell biology, Vol. 53, pp. 302-19, 2014 (Sample species: Rat (Rattus)). Further details: Western Blotting

Sagar, Kumar, Behera, Pal: "Effects of CEES and LPS synergistically stimulate oxidative stress inactivates OGG1 signaling in macrophage cells." in: Journal of hazardous materials, Vol. 278, pp. 236-49, 2014 (Sample species: Mouse (Murine)). Further details: Western Blotting

Zhang, Wang, Chen: "Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells." in: Cellular signalling, Vol. 24, Issue 5, pp. 1037-46, 2012 (Sample species: Human). Further details: Western Blotting

Csak, Dolganiuc, Kodys, Nath, Petrasek, Bala, Lippai, Szabo: "Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 6, pp. 1917-31, 2011 Further details: Western Blotting

Kamal, Sreekanth, Kumar, Shankaraiah, Balakishan, Ramaiah, Pushpavalli, Ray, Bhadra: "Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines." in: European journal of medicinal chemistry, Vol. 45, Issue 6, pp. 2173-81, 2010

Douglas, Ryu, Kanaan, Del Carmen Rivero, Dugan, Haddad, Ali: "Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction." in: American journal of physiology. Cell physiology, Vol. 298, Issue 6, pp. C1594-602, 2010 (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Zall, Weber, Besch, Zantl, Häcker: "Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1." in: Molecular cancer, Vol. 9, pp. 164, 2010 Further details: Western Blotting

Kumar, Coltas, Kumar, Chepeha, Bradford, Polverini: "Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release." in: Cancer research, Vol. 67, Issue 3, pp. 1193-202, 2007 Further details: Flow Cytometry,Immunochromatography

Zhu, Xu, Wang, Shibata, Uchiyama, Blomgren, Hagberg: "Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia." in: Journal of neurochemistry, Vol. 96, Issue 4, pp. 1016-27, 2006 (Sample species: Mouse (Murine)). Further details: Western Blotting

Yamasaki, Wada, Kumatori, Nakagawa, Funao, Nakayama, Hisatsune, Kimura, Moss, Hirayama: "Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation." in: The Journal of biological chemistry, Vol. 281, Issue 16, pp. 11250-9, 2006 Further details: Immunocytochemistry,Immunofluorescence

Meyer, Karawajew, Schrappe, Ludwig, Debatin, Stahnke: "Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL." in: Blood, Vol. 107, Issue 11, pp. 4524-31, 2006 (Sample species: Human). Further details: Cell Sorting,Flow Cytometry,Immunochromatography

Chen, Gan, Remold: "A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 6, pp. 3707-16, 2006 (Sample species: Human). Further details: Flow Cytometry,Immunochromatography

De Chiara, Marcocci, Torcia, Lucibello, Rosini, Bonini, Higashimoto, Damonte, Armirotti, Amodei, Palamara, Russo, Garaci, Cozzolino: "Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 21353-61, 2006 Further details: Western Blotting

Images

Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling References for anti-Cytochrome C Antibody (ABIN252468) back to top
Supplier Images
Western Blotting (WB) image for anti-Cytochrome C antibody (Cytochrome C, Somatic) (ABIN252468) Western blot detection of Cytochrome C in 15 ugs of HeLa cell lysate using ABIN252468...
Western Blotting (WB) image for anti-Cytochrome C antibody (Cytochrome C, Somatic) (ABIN252468) Western Blot: Cytochrome c Antibody (7H8.2C12) [ABIN2524683] - Analysis using cytochr...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cytochrome C antibody (Cytochrome C, Somatic) (ABIN252468) Immunohistochemistry-Paraffin: Cytochrome c Antibody (7H8.2C12) [ABIN2524683] - Cytoc...