We are preparing the requested document. Please wait, this may take a while...!
|Application / Reactivity||Rat (Rattus)|
|BioImaging (BI)||1 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Flow Cytometry (FACS)||136 Antibodies|
|Immunochromatography (IC)||1 Antibodies|
|Immunocytochemistry (ICC)||27 Antibodies|
|Immunofluorescence (IF)||53 Antibodies|
|Immunofluorescence (Cultured Cells) (IF (cc))||11 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||50 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||15 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||121 Antibodies|
|Immunoprecipitation (IP)||23 Antibodies|
|Intracellular Staining (ICS)||2 Antibodies|
|Neutralization (Neut)||8 Antibodies|
|Western Blotting (WB)||170 Antibodies|
|Antigen||Cytochrome C, Somatic (CYCS) Antibodies|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This Cytochrome C antibody is un-conjugated Alternatives|
Western Blotting (WB)
|8 references available|
|Supplier||Log in to see|
Product Details anti-Cytochrome C AntibodyTarget Details Cytochrome C Application Details Handling References for anti-Cytochrome C Antibody (ABIN223076) Images
|Blocking Peptide||Blocking peptide for this product available: ABIN412697|
|Specificity||The cytochrome c antibody detects the 12 kDa cytochrome c from rat samples.|
|Immunogen||Rat cytochrome c|
Target Details Cytochrome CProduct Details anti-Cytochrome C Antibody Application Details Handling References for anti-Cytochrome C Antibody (ABIN223076) Images back to top
|Alternative Name||Cytochrome C (CYCS Antibody Abstract)|
Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases.
Synonyms: CYCS, CYC
|Research Area||Apoptosis/Necrosis, Metabolism|
|Pathways||Apoptosis, Caspase Cascade in Apoptosis|
Application DetailsProduct Details anti-Cytochrome C Antibody Target Details Cytochrome C Handling References for anti-Cytochrome C Antibody (ABIN223076) Images back to top
Western blotting (0.5-4 μg/mL).
Rat kidney lysate can be used as a positive control.
However, the optimal conditions should be determined individually.
Country of Animal Origin: China
|Restrictions||For Research Use only|
HandlingProduct Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details References for anti-Cytochrome C Antibody (ABIN223076) Images back to top
|Buffer||100 μg (0.2 mg/mL) affinity purified rabbit anti-Cytochrome c polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.|
|Precaution of Use||This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
|Storage Comment||For long-term storage, aliquot and freeze at -70 °C.|
|Expiry Date||12 months|
References for anti-Cytochrome C Antibody (ABIN223076)Product Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling Images back to top
|Product cited in:||
Broselid, Cheng, Sjöström, Lövgren, Klug-De Santiago, Belting, Jirström, Malmström, Olde, Bendahl, Hartman, Fernö, Leeb-Lundberg: "G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 7, pp. 1681-92, 2013
Kotani, Akabane, Takeyasu, Ueda, Takeuchi: "Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes." in: Nucleic acids research, Vol. 41, Issue 6, pp. 3713-22, 2013
Zhao, Chen, Lu, Dong, Wang, Bi, Wu, Guo, Wu, Guo: "TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 11, pp. 4133-41, 2008
Katz, Morris, Trupin, Yazdany, Yelin: "Disability in valued life activities among individuals with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 59, Issue 4, pp. 465-73, 2008
Wang, Shen, Gao, Ye, Yang, Liang, Bruce, Luo, Xia: "Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats." in: Stroke; a journal of cerebral circulation, Vol. 39, Issue 3, pp. 983-90, 2008
Lan, Gorke, Rau, Zeisel, Hildt, Himmelsbach, Carvajal-Yepes, Huber, Wakita, Schmitt-Graeff, Royer, Blum, Fischer, Baumert: "Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4926-35, 2008
Kuhn, Chen, Voorhees, Strader, Shenk, Sun, Demo, Bennett, van Leeuwen, Chanan-Khan, Orlowski: "Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma." in: Blood, Vol. 110, Issue 9, pp. 3281-90, 2007
Machiya, Shibata, Yamauchi, Hirama, Wada, Inoue, Abe, Takabatake, Sata, Kubota: "Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure." in: American journal of respiratory cell and molecular biology, Vol. 36, Issue 4, pp. 418-26, 2007
ImagesProduct Details anti-Cytochrome C Antibody Target Details Cytochrome C Application Details Handling References for anti-Cytochrome C Antibody (ABIN223076) back to top