anti-Human DFFB antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended DFFB Antibody (supplied by: Log in to see )

Antigen
DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) Antibodies
  • LOC100223514
  • CAD
  • CPAN
  • DFF-40
  • DFF2
  • DFF40
  • Cad
  • 40kDa
  • 5730477D02Rik
  • Didff
  • DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
  • DNA fragmentation factor, beta subunit
  • DFFB
  • LOC100223514
  • Dffb
Reactivity
Human, Mouse (Murine), Rat (Rattus)
126
75
58
Host
Rabbit
128
29
Clonality
Polyclonal
Conjugate
This DFFB antibody is conjugated to Alexa Fluor 350
6
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
128
37
26
25
21
20
18
9
5
3
1
1
1
Options
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Catalog No. ABIN893943
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN893950 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN893947 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN2812360 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN893937 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN893949 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN893939 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN893933 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN893944 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN893934 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN872776 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN5001210 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal
1 ABIN5001211 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal

Similar anti-DFFB Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Western Blotting (WB) 109 Antibodies 51 Antibodies 34 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies 14 Antibodies 10 Antibodies
Immunohistochemistry (IHC) 6 Antibodies 22 Antibodies 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies 26 Antibodies 13 Antibodies
Immunofluorescence (IF) 6 Antibodies 9 Antibodies

General

Antigen DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(126), (75), (58)
Host Rabbit
(128), (29)
Clonality
Polyclonal
Conjugate This DFFB antibody is conjugated to Alexa Fluor 350
(6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(128), (37), (26), (25), (21), (20), (18), (9), (5), (3), (1), (1), (1)
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Product Details anti-DFFB Antibody

Target Details DFFB Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DFFB
Isotype IgG

Target Details DFFB

Product Details anti-DFFB Antibody Application Details Handling Images back to top
Antigen
Alternative Name Dffb (DFFB Antibody Abstract)
Background

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined. [provided by RefSeq, Jul 2008].

Synonyms: CAD, Caldesmon, Caspase activated deoxyribonuclease, Caspase activated DNase, Caspase activated nuclease, CDM, CPAN, Deoxyribonuclease III, caspase activated, DFF 40, DFF2, DFF40, Didff, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor subunit beta, DNA fragmentation factor, 40 Da, beta polypeptide caspase activated DNase, DNA fragmentation factor, 40 kD beta subunit, DNA fragmentation factor, 40 kD, beta polypeptide, DNA fragmentation factor, 40 kDa, beta polypeptide caspase activated DNase, DNA fragmentation factor, 40 kDa, beta polypeptide caspase-activated DNase, DNAation factor, beta subunit, DFFB_HUMAN.

Gene ID 1677
Research Area Chromatin and Nuclear Signaling, Cell Cycle, Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-DFFB Antibody Target Details DFFB Handling Images back to top
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-DFFB Antibody Target Details DFFB Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months