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|Application / Reactivity||Human||Mouse (Murine)||Dog (Canine)|
|Western Blotting (WB)||193 Antibodies||66 Antibodies||3 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Immunoprecipitation (IP)||24 Antibodies||7 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||32 Antibodies||5 Antibodies||1 Antibodies|
|Immunohistochemistry (IHC)||55 Antibodies||38 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||1 Antibodies||1 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||15 Antibodies||2 Antibodies|
|Immunocytochemistry (ICC)||8 Antibodies||1 Antibodies|
|Antigen||Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies|
|Reactivity||Dog (Canine), Human, Mouse (Murine) Alternatives|
|Conjugate||This FADD antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Western Blotting (WB)
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Product Details anti-FADD AntibodyTarget Details FADD Application Details Handling Images
|Specificity||The antibody detects 28 kDa protein, corresponding to the apparent molecular weight of FADD in SDS-PAGE|
|Immunogen||Recombinant human FADD|
Target Details FADDProduct Details anti-FADD Antibody Application Details Handling Images back to top
|Alternative Name||FADD (FADD Antibody Abstract)|
Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 24 kDa cytosolic protein. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas, an association mediated by their homologous death domains. Overexpression of FADD induces apoptosis that can be inhibited by CrmA, a poxvirus protein that blocks both Fas- and TNF-induced cell death.
Synonyms: FAS-associated death domain protein, GIG3, MGC8528, MORT1
|Research Area||Cancer, Apoptosis/Necrosis|
|Pathways||Apoptosis, TLR Signaling|
Application DetailsProduct Details anti-FADD Antibody Target Details FADD Handling Images back to top
Western blot analysis (1-4 μg/mL).
HeLa cell lysate can be used as a positive control.
However, the optimal conditions should be determined individually.
Country of Animal Origin: USA
|Restrictions||For Research Use only|
HandlingProduct Details anti-FADD Antibody Target Details FADD Application Details Images back to top
|Buffer||100 μg (200 μg/mL) affinity purified antibody in PBS containing 30 % glycerol, 0.5 % BSA and 0.01 % thimerosal|
|Precaution of Use||This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
|Storage Comment||For long-term storage, aliquot and freeze at -70 °C.|
|Expiry Date||12 months|