You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) FADD antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended FADD Antibody (supplied by: Log in to see )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
  • MORT1
  • Mort1
  • Mort1/FADD
  • TNFRSF6
Epitope
pSer191
27
27
24
22
18
16
13
11
8
7
6
5
4
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine)
210
71
34
7
3
3
2
1
Host
Rabbit
173
91
Clonality
Polyclonal
Conjugate
This FADD antibody is un-conjugated
11
10
9
7
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
230
146
75
36
22
15
12
9
5
4
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN684643
$ 291.50
Plus shipping costs $45.00

Similar anti-FADD Antibodies

Application / Reactivity Mouse (Murine)
ELISA 34 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 39 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 67 Antibodies

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
Epitope pSer191
(27), (27), (24), (22), (18), (16), (13), (11), (8), (7), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(210), (71), (34), (7), (3), (3), (2), (1)
Host Rabbit
(173), (91)
Clonality
Polyclonal
Conjugate This FADD antibody is un-conjugated
(11), (10), (9), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(230), (146), (75), (36), (22), (15), (12), (9), (5), (4), (4), (2), (1), (1)
Supplier Log in to see

Product Details anti-FADD Antibody

Target Details FADD Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse FADD around the phosphorylation site of Ser191 [NM(p-S)PV]
Isotype IgG

Target Details FADD

Product Details anti-FADD Antibody Application Details Handling Images back to top
Antigen
Alternative Name Fadd (FADD Antibody Abstract)
Background

FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C terminal death domain that interacts with the Fas receptor death domain. The N terminus contains a death effectors domain (DED) which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. Recruitment of Caspase 8 to the Fas receptor results in oligomerization of the Caspase 8 protein, which in turn drives its autoactivation through self-cleavage. Activated Caspase 8 then activates other downstream caspases including Caspase 9, thereby commiting the cell to undergo apoptosis. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL induced transcriptional activation of cfos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK 293 cell line.


Synonyms: FADD phospho S191, p-FADD phospho S191, FADD protein, Fas TNFRSF6 associated via death domain, Fas associated via death domain, Fas associating death domain containing protein, Fas associating protein, Fas associating protein with death domain, Fas TNFRSF6 associated via death domain, GIG 3, GIG3, Growth inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity, MGC8528, MORT 1, MORT1, FADD_MOUSE.
Gene ID 14082
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, TLR Signaling

Application Details

Product Details anti-FADD Antibody Target Details FADD Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FADD Antibody Target Details FADD Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months