anti-Mouse (Murine) FADD antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended FADD Antibody (supplied by: Log in to see )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • Fas (TNFRSF6)-associated via death domain
  • FADD
  • Fadd
Epitope
pSer191
32
28
26
20
20
17
15
9
7
6
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
225
81
38
11
3
2
Host
Rabbit
178
99
Clonality
Polyclonal
Conjugate
This FADD antibody is un-conjugated
11
10
9
7
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
246
145
88
49
30
18
14
8
5
4
4
3
1
1
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Catalog No. ABIN684643
$ 317.90
Plus shipping costs $45.00

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
Epitope pSer191
(32), (28), (26), (20), (20), (17), (15), (9), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(225), (81), (38), (11), (3), (2)
Host Rabbit
(178), (99)
Clonality
Polyclonal
Conjugate This FADD antibody is un-conjugated
(11), (10), (9), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(246), (145), (88), (49), (30), (18), (14), (8), (5), (4), (4), (3), (1), (1)
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Product Details anti-FADD Antibody

Target Details FADD Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse FADD around the phosphorylation site of Ser191 [NM(p-S)PV]
Isotype IgG

Target Details FADD

Product Details anti-FADD Antibody Application Details Handling Images back to top
Antigen
Alternative Name Fadd (FADD Antibody Abstract)
Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).

Subcellular location: Intracellular

Synonyms: Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1

Gene ID 14082
UniProt Q61160
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-FADD Antibody Target Details FADD Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-FADD Antibody Target Details FADD Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months