anti-Rat (Rattus) FADD antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FADD Antibody (supplied by: Log in to see )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • Fas (TNFRSF6)-associated via death domain
  • FADD
  • Fadd
Epitope
AA 10-60
32
29
26
20
19
17
15
9
7
6
5
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
224
81
37
11
3
2
Host
Rabbit
178
99
Clonality
Polyclonal
Conjugate
This FADD antibody is un-conjugated
11
10
9
7
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
246
145
88
49
30
18
15
8
5
4
4
3
1
1
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Catalog No. ABIN669471
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN669480 IHC (p) WB HRP Rabbit IgG AA 10-60 Log in to see Polyclonal
1 ABIN675333 IHC (p) WB HRP Rabbit IgG pSer194 Log in to see Polyclonal
1 ABIN669473 IHC (p) WB Biotin Rabbit IgG AA 10-60 Log in to see Polyclonal
1 ABIN675326 IHC (p) WB Biotin Rabbit IgG pSer194 Log in to see Polyclonal
1 ABIN675324 IF (p) IHC (p) WB Rabbit IgG pSer194 Log in to see Polyclonal

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antibodies
Epitope AA 10-60
(32), (29), (26), (20), (19), (17), (15), (9), (7), (6), (5), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(224), (81), (37), (11), (3), (2)
Host Rabbit
(178), (99)
Clonality
Polyclonal
Conjugate This FADD antibody is un-conjugated
(11), (10), (9), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(246), (145), (88), (49), (30), (18), (15), (8), (5), (4), (4), (3), (1), (1)
Pubmed 1 reference available
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Product Details anti-FADD Antibody

Target Details FADD Application Details Handling References for anti-FADD antibody (ABIN669471) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse FADD
Isotype IgG

Target Details FADD

Product Details anti-FADD Antibody Application Details Handling References for anti-FADD antibody (ABIN669471) Images back to top
Antigen
Alternative Name FADD (FADD Antibody Abstract)
Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).

Subcellular location: Cytoplasm, Nucleus

Synonyms: Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1

Gene ID 14082
UniProt Q61160
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-FADD Antibody Target Details FADD Handling References for anti-FADD antibody (ABIN669471) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only

Handling

Product Details anti-FADD Antibody Target Details FADD Application Details References for anti-FADD antibody (ABIN669471) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-FADD antibody (ABIN669471)

Product Details anti-FADD Antibody Target Details FADD Application Details Handling Images back to top
Product cited in:

Soni, Adebiyi: "Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis." in: Renal failure, pp. 1-12, 2016

Images

Product Details anti-FADD Antibody Target Details FADD Application Details Handling References for anti-FADD antibody (ABIN669471) back to top
Supplier Images
SDS-PAGE (SDS) image for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 10-60) antibody (ABIN669471) L1 mouse liver lysates, L2 mouse brain lysates probed with Anti FADD Polyclonal Antib...