anti-Human FASL antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FASL Antibody (supplied by: Log in to see )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand (TNF superfamily, member 6)
  • Fas (TNF receptor superfamily, member 6)
  • fas ligand
  • faslg
  • FAS
  • FASLG
  • fas
  • LOC100344073
  • Fasl
  • Faslg
Epitope
AA 170-220
26
19
17
15
12
9
9
7
7
6
5
5
5
5
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
421
171
88
36
7
5
5
3
3
2
1
1
Host
Rabbit
257
175
49
32
29
8
1
Clonality
Polyclonal
Conjugate
This FASL antibody is un-conjugated
44
31
27
12
12
9
9
9
9
8
8
8
8
8
7
6
6
4
3
2
2
2
2
2
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
312
257
125
96
78
75
51
47
28
28
12
12
10
10
7
5
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN726410
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.569977 ABIN1105940 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
11.569977 ABIN462004 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
11.569977 ABIN615525 IHC (p) WB Rabbit Log in to see Polyclonal
11.569977 ABIN615080 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
11.569977 ABIN615086 IHC (p) Rabbit N-Term Log in to see Polyclonal
11.569977 ABIN4310551 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN155064 IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see I-6060
1 ABIN265415 IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN3043159 IHC (p) WB Rabbit IgG AA 263-281, C-Term Log in to see Polyclonal 7
1 ABIN1688341 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN574121 IHC (p) WB Rabbit AA 82-145 Log in to see Polyclonal
1 ABIN1687041 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2889193 IHC (p) ELISA WB Rabbit IgG AA 101-150 Log in to see Polyclonal
1 ABIN1492926 ICC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1494375 IHC (p) Rabbit N-Term Log in to see Polyclonal
1 ABIN187308 EIA Func FACS IHC (fro) IHC (p) IP Mouse IgG1 Log in to see 5G51 1
1 ABIN726419 IHC (p) WB HRP Rabbit IgG AA 170-220 Log in to see Polyclonal
1 ABIN609580 ICC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN465173 IHC (p) Neut ELISA WB Goat Log in to see Polyclonal
1 ABIN726412 IHC (p) WB Biotin Rabbit IgG AA 170-220 Log in to see Polyclonal

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
Epitope AA 170-220
(26), (19), (17), (15), (12), (9), (9), (7), (7), (6), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(421), (171), (88), (36), (7), (5), (5), (3), (3), (2), (1), (1)
Host Rabbit
(257), (175), (49), (32), (29), (8), (1)
Clonality
Polyclonal
Conjugate This FASL antibody is un-conjugated
(44), (31), (27), (12), (12), (9), (9), (9), (9), (8), (8), (8), (8), (8), (7), (6), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(312), (257), (125), (96), (78), (75), (51), (47), (28), (28), (12), (12), (10), (10), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-FASL Antibody

Target Details FASL Application Details Handling ProductDetails: References for anti-FASL antibody (ABIN726410) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Fas Ligand
Isotype IgG

Target Details FASL

Product Details anti-FASL Antibody Application Details Handling ProductDetails: References for anti-FASL antibody (ABIN726410) Images back to top
Antigen
Alternative Name Fas Ligand (FASL Antibody Abstract)
Background

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Subcellular location: Extracellular

Synonyms: APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, APT1LG1, Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, CD95 ligand, Fas antigen ligand, Fas ligand, FASLG

Gene ID 356
UniProt P48023
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, Innate Immunity, Cytokines, Apoptosis/Necrosis, CD Antigens, Virology, Cancer, Surface Receptors of Immune Cells
Pathways Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FASL Antibody Target Details FASL Handling ProductDetails: References for anti-FASL antibody (ABIN726410) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-FASL Antibody Target Details FASL Application Details ProductDetails: References for anti-FASL antibody (ABIN726410) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-FASL antibody (ABIN726410)

Product Details anti-FASL Antibody Target Details FASL Application Details Handling Images back to top
Product cited in:

Lv, Zheng, Zhou, Jia, Wang, Liu, Zhao, Ji, Li, Cao: "Antiproliferative and Apoptosis-inducing Effect of exo-Protoporphyrin IX based Sonodynamic Therapy on Human Oral Squamous Cell Carcinoma." in: Scientific reports, Vol. 7, pp. 40967, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Wang, Zhang, Yang, Luo, Zhang, Wang: "Lipopolysaccharide-induced expression of FAS ligand in cultured immature boar sertoli cells through the regulation of pro-inflammatory cytokines and miR-187." in: Molecular reproduction and development, 2015

Song, Li, Shi, Lehmler, Fu, Su, Xia, Song, Song: "Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells." in: Chemical research in toxicology, Vol. 28, Issue 11, pp. 2160-9, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Qi, Fu, Wang, Liu, Quan, Kourouma, Yan, Yu, Duan, Yang: "BPA-induced apoptosis of rat Sertoli cells through Fas/FasL and JNKs/p38 MAPK pathways." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 50, pp. 108-16, 2014

Chen, Xie, Xue, Ji, Chang, Ma, Bi: "Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius." in: Research in veterinary science, Vol. 94, Issue 3, pp. 496-503, 2013

Shi, Song, Wang, Wang, Liang, Hu, Yu, Guan, Cheng, Yang: "β-Benzene hexachloride induces apoptosis of rat Sertoli cells through generation of reactive oxygen species and activation of JNKs and FasL." in: Environmental toxicology, Vol. 26, Issue 2, pp. 124-35, 2011

Shi, Song, Wang, Liang, Hu, Guan, Cheng, Yang: "p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway." in: Journal of biomedicine & biotechnology, Vol. 2009, pp. 181282, 2009

Images

Product Details anti-FASL Antibody Target Details FASL Application Details Handling ProductDetails: References for anti-FASL antibody (ABIN726410) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-FasL Polyclo...
Immunohistochemistry (IHC) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: human rectal carcinoma labeled with Anti-FasL P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: human rectal carcinoma labeled with Anti-FasL P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 170-220) antibody (ABIN726410) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-FasL Polyclo...