anti-Rat (Rattus) FASL antibody for Flow Cytometry

Recommended FASL Antibody (supplied by: Log in to see )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand (TNF superfamily, member 6)
  • Fas (TNF receptor superfamily, member 6)
  • fas ligand
  • faslg
  • FAS
  • FASLG
  • fas
  • LOC100344073
  • Fasl
  • Faslg
Reactivity
Mouse (Murine), Rat (Rattus)
422
173
88
36
7
5
5
3
3
2
1
1
Host
Hamster
259
176
48
32
29
8
1
Clonality
Monoclonal
Conjugate
This FASL antibody is conjugated to FITC
45
31
26
12
12
9
9
9
9
8
8
8
8
8
7
6
6
4
3
2
2
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
313
258
125
97
80
75
51
47
28
28
13
12
10
10
7
5
3
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN614573
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.117655 ABIN614579 FACS PE Hamster IgG Log in to see MFL4 3
14.117655 ABIN2478831 FACS Hamster IgG Log in to see MFL4 3
14.117655 ABIN1176980 BR FACS Armenian Hamster IgG3, kappa Log in to see MFL4 11
14.117655 ABIN447421 FACS FITC Armenian Hamster IgG Log in to see MFL4
14.117655 ABIN2665564 FACS IF IHC Hamster IgG Log in to see MFL4 6
14.117655 ABIN2660964 FACS Biotin Hamster IgG Log in to see MFL4 6
1 ABIN614575 Func FACS Hamster IgG Log in to see MFL4 3
1 ABIN614577 FACS Hamster IgG Log in to see MFL4 3
1 ABIN2689026 FACS Biotin Armenian Hamster IgG3, kappa Log in to see MFL4 10
1 ABIN2478838 Func FACS Hamster IgG Log in to see MFL4 3
1 ABIN2689023 BR FACS Armenian Hamster IgG3, kappa Log in to see MFL4 11
1 ABIN2478836 FACS FITC Hamster IgG Log in to see MFL4 3
1 ABIN2478839 FACS PE Hamster IgG Log in to see MFL4 3
1 ABIN2478834 FACS Alexa Fluor 647 Hamster IgG Log in to see MFL4 3
1 ABIN1819963 FACS PE Hamster IgG Log in to see MFL4
1 ABIN1820435 FACS Biotin Hamster IgG Log in to see MFL4
1 ABIN1819962 FACS Hamster IgG Log in to see MFL4
1 ABIN1820310 FACS Hamster IgG Log in to see
1 ABIN1820315 FACS Hamster IgG Log in to see
1 ABIN1819961 FACS FITC Hamster IgG Log in to see MFL4

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(422), (173), (88), (36), (7), (5), (5), (3), (3), (2), (1), (1)
Host Hamster
(259), (176), (48), (32), (29), (8), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FASL antibody is conjugated to FITC
(45), (31), (26), (12), (12), (9), (9), (9), (9), (8), (8), (8), (8), (8), (7), (6), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(313), (258), (125), (97), (80), (75), (51), (47), (28), (28), (13), (12), (10), (10), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FASL Antibody

Target Details FASL Application Details Handling References for anti-FASL antibody (ABIN614573) Images
Specificity Recognizes both Mouse and Rat CD178. Clone MFL4 is reported to block CD178/CD95 induced apoptosis. We recommend the use of AM20860LE-N for functional studies.
Purification Affinity Chromatography on Protein G
Immunogen B6 Mouse FasL/BHK cells.
Clone MFL4
Isotype IgG

Target Details FASL

Product Details anti-FASL Antibody Application Details Handling References for anti-FASL antibody (ABIN614573) Images back to top
Antigen
Alternative Name CD178 / Fas Ligand (FASL Antibody Abstract)
Background CD178, otherwise known as Fas Ligand/ CD95L, a 40 kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
Gene ID 14103
NCBI Accession NP_034307
UniProt P41047
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FASL Antibody Target Details FASL Handling References for anti-FASL antibody (ABIN614573) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FASL Antibody Target Details FASL Application Details References for anti-FASL antibody (ABIN614573) Images back to top
Concentration 0.1 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light.

References for anti-FASL antibody (ABIN614573)

Product Details anti-FASL Antibody Target Details FASL Application Details Handling Images back to top
Background publications

Watanabe, Yoshida, Shirai, Yamori, Yagita, Itoh, Chiba, Kita, Wakatsuki: "Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 5, pp. 2188-99, 2002

Trinité, Voisine, Yagita, Josien: "A subset of cytolytic dendritic cells in rat." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 8, pp. 4202-8, 2000

Kayagaki, Yamaguchi, Nagao, Matsuo, Maeda, Okumura, Yagita: "Polymorphism of murine Fas ligand that affects the biological activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3914-9, 1997

Images

Product Details anti-FASL Antibody Target Details FASL Application Details Handling References for anti-FASL antibody (ABIN614573) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody (FITC) (ABIN614573) anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody (FITC)