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anti-Rat (Rattus) FASL antibody for Immunofluorescence

Recommended FASL Antibody (supplied by: Log in to see )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
  • ALPS1B
  • APT1LG1
  • Apt1Lg1
  • APTL
  • CD95-L
  • CD95L
  • CD178
  • FAS
  • Fas-L
  • FASL
  • fasl
  • Fasl
  • Faslg
  • FASLG
  • gld
  • TNFRSF6
  • Tnfsf6
  • TNFSF6
  • zgc:162027
Reactivity
Mouse (Murine), Rat (Rattus)
275
137
64
3
3
1
1
1
1
1
Host
Hamster
146
127
60
29
12
6
Clonality
Monoclonal
Conjugate
This FASL antibody is un-conjugated
32
26
18
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
196
162
87
63
56
50
30
29
16
12
11
11
11
6
3
3
2
2
1
1
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2665564
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Top referenced anti-FASL antibody for Immunofluorescence

Similar anti-FASL Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies 3 Antibodies
ELISA 5 Antibodies 8 Antibodies
Flow Cytometry (FACS) 16 Antibodies 90 Antibodies
Functional Studies (Func) 2 Antibodies 6 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 8 Antibodies
Immunofluorescence (IF) 1 Antibodies 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 10 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 32 Antibodies
Immunochromatography (IC) 3 Antibodies

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(275), (137), (64), (3), (3), (1), (1), (1), (1), (1)
Host Hamster
(146), (127), (60), (29), (12), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FASL antibody is un-conjugated
(32), (26), (18), (5), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(196), (162), (87), (63), (56), (50), (30), (29), (16), (12), (11), (11), (11), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-FASL Antibody

Target Details FASL Application Details Handling References for anti-FASL Antibody (ABIN2665564) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone MFL4
Isotype IgG

Target Details FASL

Product Details anti-FASL Antibody Application Details Handling References for anti-FASL Antibody (ABIN2665564) Images back to top
Antigen
Alternative Name CD178 (FASL Antibody Abstract)
Background CD178 is a 40 kD member of the TNF/NGF superfamily also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. Cell surface CD178 is expressed on activated T cells and in testis and eye. CD178 is upregulated in activated T cells upon TCR re-engagement and has been shown to induce autocrine and paracrine T cell death. CD178 expression in the eye and testis has been shown to participate in immune privilege at these sites. CD178 can be cleaved from the surface by metalloproteases, and "soluble" CD178 may block the activities of membrane-bound CD178. CD178 binds to CD95 (Fas) to induce apoptotic cell death implicated in the maintenance of peripheral tolerance. CD178/CD95 interactions have also been implicated in the proliferation of CD8+ cells and neutrophil extravasation, chemotaxis, and survival. The MFL4 antibody recognizes CD178 in a wide array of mouse strains and has been reported to block CD178/CD95 induced apoptosis. The MFL4 antibody is cross-reactive with rat and mouse FasL.
Pathways Apoptosis, EGFR Signaling Pathway

Application Details

Product Details anti-FASL Antibody Target Details FASL Handling References for anti-FASL Antibody (ABIN2665564) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FASL Antibody Target Details FASL Application Details References for anti-FASL Antibody (ABIN2665564) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-FASL Antibody (ABIN2665564)

Product Details anti-FASL Antibody Target Details FASL Application Details Handling Images back to top
Background publications

Chang, Chang, Lee, Chiang, Chuang, Kuo, Yang: "Cytopiloyne, a polyacetylenic glucoside, prevents type 1 diabetes in nonobese diabetic mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 11, pp. 6984-93, 2007

Borges, Falcão, Leite-Júnior, Alvim, Teixeira, Russo, Nóbrega, Lopes, Rocco, Davidson, Linden, Yagita, Zin, DosReis: "Fas ligand triggers pulmonary silicosis." in: The Journal of experimental medicine, Vol. 194, Issue 2, pp. 155-64, 2001

Trinité, Voisine, Yagita, Josien: "A subset of cytolytic dendritic cells in rat." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 8, pp. 4202-8, 2000

Hill, Ouhtit, Loughlin, Kripke, Ananthaswamy, Owen-Schaub: "Fas ligand: a sensor for DNA damage critical in skin cancer etiology." in: Science (New York, N.Y.), Vol. 285, Issue 5429, pp. 898-900, 1999

Kayagaki, Yamaguchi, Nagao, Matsuo, Maeda, Okumura, Yagita: "Polymorphism of murine Fas ligand that affects the biological activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3914-9, 1997

Takahashi, Tanaka, Brannan, Jenkins, Copeland, Suda, Nagata: "Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand." in: Cell, Vol. 76, Issue 6, pp. 969-76, 1994

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-FASL antibody (Fas Ligand (TNF Superfamily, Member 6)) (ABIN2665564) anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody