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Browse our anti-GZMB (Gzmb) Antibodies

Full name:
anti-Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) Antibodies (Gzmb)
On www.antibodies-online.com are 0 Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) Antibodies from different suppliers available. Additionally we are shipping GZMB Kits (2) and many more products for this protein. A total of 2 GZMB products are currently listed.
Synonyms:
AI553453, BDMD1, CCP-1/C11, CCP1, CCPI, CGL-1, CGL1, CSP-B, CSPB, Ctla-1, CTLA1, CTSGL1, GZB, GZMB, GZMH, HLP, RNKP-1, SECT
list all antibodies Gene Name GeneID UniProt
Anti-Mouse Gzmb Gzmb 14939 P04187
Anti-Human Gzmb Gzmb 3002 P10144
Anti-Rat Gzmb Gzmb 171528 P18291

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More Antibodies against GZMB Interaction Partners

Mouse (Murine) Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. Released granzyme B induces DNA fragmentation in intraepithelial lymphocytes independently of Perforin (show PRF1 Antibodies)

  2. serglycin (show SRGN Antibodies) plays a critical role in the maturation of dense-core cytotoxic granules in cytotoxic lymphocytes and the trafficking and storage of perforin (show PRF1 Antibodies) and granzyme B, whereas granzyme A (show GZMA Antibodies) is unaffected

  3. these results suggest a perforin (show PRF1 Antibodies)-independent, extracellular role for GzmB in the pathogenesis of cardiac fibrosis

  4. data indicate an involvement of granzyme B in the neuroinflammation mediated by Eomes (show EOMES Antibodies)(+) CD4 (show CD4 Antibodies)(+) T cells.

  5. Data suggest that targeting granzyme B (GzmB) in selected T cell subsets may provide a strategy to control graft-versus-host disease (GVHD).

  6. These findings indicate a significant role for GzmB in extracellular matrix degradation that may have implications in many age-related chronic inflammatory diseases.

  7. Different natural variants of granzyme B have a profound impact on the immune response to a common and authentic viral pathogen.

  8. Visualization of granzyme B-expressing CD8 (show CD8A Antibodies) T cells during primary and secondary immune responses to Listeria monocytogenes.

  9. The mitochondrial apoptotic pathway activated via Bim (show BCL2L11 Antibodies) is critically involved in apoptosis induced by mouse granzyme B.

  10. The results, in susceptible B6 mice for GzmB and in resistant 129/Sv mice for GzmA (show GZMA Antibodies) and/or the GzmB cluster, point to granzyme-mediated host defense regulation in the liver in experimental visceral leishmaniasis.

Human Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. Increased TIM3 (show HAVCR2 Antibodies)+CD8 (show CD8A Antibodies)+T cells with lower perforin (show PRF1 Antibodies) and granzyme B expression and higher CD95 (show FAS Antibodies) expression in MDS (show PAFAH1B1 Antibodies) patients were observed.

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin (show PRF1 Antibodies), GrA (show NR3C1 Antibodies), GrB, Gr3 (show PRLHR Antibodies)/K, and GRN (show GRN Antibodies) in NK-92CI cells.

  3. granzyme-B levels were found to be significantly associated with increased insulin (show INS Antibodies) resistance in adolescent polycystic ovary syndrome patients. Additionally, elevated levels of serum granzyme-B were predictive for increased cardiovascular risk in PCOS patients

  4. results suggest that enhanced IL-21R (show IL21R Antibodies) expression of CD19 (show CD19 Antibodies)(+)CD5 (show CD5 Antibodies)(+) B cells and production of IL-21 (show IL17C Antibodies) by iNKT cells may play an important role in the pathogenesis of pSS (show CDSN Antibodies) by regulating CD19 (show CD19 Antibodies)(+)CD5 (show CD5 Antibodies)(+) B cell functions and increasing GrB production, presumably leading to a counter-regulatory effect in the disease.

  5. Findings show that GrB was produced in 57.1% colorectal cancer cell (CRC (show CALR Antibodies)) lines and 100% CRC (show CALR Antibodies)-derived Cancer Stem Cells and present a novel role for GrB as up-modulator of epitelial-to-mesenchimal transition in CRC (show CALR Antibodies) cells.

  6. FASL (show FASL Antibodies), granzyme B, and cytochrome c (show CYCS Antibodies) blood expression reflects breast cancer progression and response to therapy. (Review)

  7. Data show that NK cell lines could secreted rapidly inactive Mr 35 000 granzyme B (GZB)outside secretory lysosomes (SLs (show ALDH3A2 Antibodies)).

  8. Data suggest that reactive oxygen species (ROS (show ROS1 Antibodies)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9 (show SERPINB9 Antibodies).

  9. Delivered into parasite infected cells by granulysin (show GNLY Antibodies) and perforin (show PRF1 Antibodies), granzymes generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  10. Results reveal enhanced intra- and extracellular expression of gzmA (show GZMA Antibodies) and B in patients with pulmonary TB, suggesting that gzms are part of the host response to tuberculosis.

Cow (Bovine) Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. It is a cytotoxic genes in the endometrium and hightly expressed in the peri (show PLIN1 Antibodies)-implantation endometrium.

GZMB (Gzmb) Antigen Profile

Antigen Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Alternative names and synonyms associated with GZMB (Gzmb)

  • granzyme B (GZMB) antibody
  • granzyme B (Gzmb) antibody
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) antibody
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (Gzmb) antibody
  • AI553453 antibody
  • BDMD1 antibody
  • CCP-1/C11 antibody
  • CCP1 antibody
  • CCPI antibody
  • CGL-1 antibody
  • CGL1 antibody
  • CSP-B antibody
  • CSPB antibody
  • Ctla-1 antibody
  • CTLA1 antibody
  • CTSGL1 antibody
  • GZB antibody
  • GZMB antibody
  • GZMH antibody
  • HLP antibody
  • RNKP-1 antibody
  • SECT antibody

Protein level used designations for Gzmb

granzyme B , cytotoxic cell protease 1 , fragmentin-2 , granzyme B(G,H) , C11 , CTLA-1 , T-cell serine protease 1-3E , cathepsin G-like 1 , cytotoxic T-lymphocyte proteinase 2 , cytotoxic serine protease B , fragmentin 2 , human lymphocyte protein , GLP I , GLP III , GLP-1 , fragmentin , granzyme-like protein 1 , granzyme-like protein I , natural killer cell protease 1 , granzyme H , duodenase I , duodenase-1 , duodenum serine protease

GENE ID SPECIES
100127106 Felis catus
14939 Mus musculus
3002 Homo sapiens
171528 Rattus norvegicus
452825 Pan troglodytes
716518 Macaca mulatta
100233184 Sus scrofa
508646 Bos taurus
281731 Bos taurus
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