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Browse our GZMB (Gzmb) ELISA Kits

Full name:
Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) ELISA Kits (Gzmb)
On www.antibodies-online.com are 2 Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) ELISA Kits from 1 different suppliers available. A total of 2 GZMB products are currently listed.
Synonyms:
AI553453, BDMD1, CCP-1/C11, CCP1, CCPI, CGL-1, CGL1, CSP-B, CSPB, Ctla-1, CTLA1, CTSGL1, GZB, GZMB, GZMH, HLP, RNKP-1, SECT
list all ELISA KIts Gene Name GeneID UniProt
Gzmb 14939 P04187
Gzmb 3002 P10144
Rat Gzmb Gzmb 171528 P18291

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GZMB (Gzmb) ELISA Kits by Reactivity

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Mouse (Murine) Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. Released granzyme B induces DNA fragmentation in intraepithelial lymphocytes independently of Perforin (show PRF1 ELISA Kits)

  2. serglycin (show SRGN ELISA Kits) plays a critical role in the maturation of dense-core cytotoxic granules in cytotoxic lymphocytes and the trafficking and storage of perforin (show PRF1 ELISA Kits) and granzyme B, whereas granzyme A (show GZMA ELISA Kits) is unaffected

  3. these results suggest a perforin (show PRF1 ELISA Kits)-independent, extracellular role for GzmB in the pathogenesis of cardiac fibrosis

  4. data indicate an involvement of granzyme B in the neuroinflammation mediated by Eomes (show EOMES ELISA Kits)(+) CD4 (show CD4 ELISA Kits)(+) T cells.

  5. Data suggest that targeting granzyme B (GzmB) in selected T cell subsets may provide a strategy to control graft-versus-host disease (GVHD).

  6. These findings indicate a significant role for GzmB in extracellular matrix degradation that may have implications in many age-related chronic inflammatory diseases.

  7. Different natural variants of granzyme B have a profound impact on the immune response to a common and authentic viral pathogen.

  8. Visualization of granzyme B-expressing CD8 (show CD8A ELISA Kits) T cells during primary and secondary immune responses to Listeria monocytogenes.

  9. The mitochondrial apoptotic pathway activated via Bim (show BCL2L11 ELISA Kits) is critically involved in apoptosis induced by mouse granzyme B.

  10. The results, in susceptible B6 mice for GzmB and in resistant 129/Sv mice for GzmA (show GZMA ELISA Kits) and/or the GzmB cluster, point to granzyme-mediated host defense regulation in the liver in experimental visceral leishmaniasis.

Human Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. Increased TIM3 (show HAVCR2 ELISA Kits)+CD8 (show CD8A ELISA Kits)+T cells with lower perforin (show PRF1 ELISA Kits) and granzyme B expression and higher CD95 (show FAS ELISA Kits) expression in MDS (show PAFAH1B1 ELISA Kits) patients were observed.

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin (show PRF1 ELISA Kits), GrA (show NR3C1 ELISA Kits), GrB, Gr3 (show PRLHR ELISA Kits)/K, and GRN (show GRN ELISA Kits) in NK-92CI cells.

  3. granzyme-B levels were found to be significantly associated with increased insulin (show INS ELISA Kits) resistance in adolescent polycystic ovary syndrome patients. Additionally, elevated levels of serum granzyme-B were predictive for increased cardiovascular risk in PCOS patients

  4. results suggest that enhanced IL-21R (show IL21R ELISA Kits) expression of CD19 (show CD19 ELISA Kits)(+)CD5 (show CD5 ELISA Kits)(+) B cells and production of IL-21 (show IL17C ELISA Kits) by iNKT cells may play an important role in the pathogenesis of pSS (show CDSN ELISA Kits) by regulating CD19 (show CD19 ELISA Kits)(+)CD5 (show CD5 ELISA Kits)(+) B cell functions and increasing GrB production, presumably leading to a counter-regulatory effect in the disease.

  5. Findings show that GrB was produced in 57.1% colorectal cancer cell (CRC (show CALR ELISA Kits)) lines and 100% CRC (show CALR ELISA Kits)-derived Cancer Stem Cells and present a novel role for GrB as up-modulator of epitelial-to-mesenchimal transition in CRC (show CALR ELISA Kits) cells.

  6. FASL (show FASL ELISA Kits), granzyme B, and cytochrome c (show CYCS ELISA Kits) blood expression reflects breast cancer progression and response to therapy. (Review)

  7. Data show that NK cell lines could secreted rapidly inactive Mr 35 000 granzyme B (GZB)outside secretory lysosomes (SLs (show ALDH3A2 ELISA Kits)).

  8. Data suggest that reactive oxygen species (ROS (show ROS1 ELISA Kits)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9 (show SERPINB9 ELISA Kits).

  9. Delivered into parasite infected cells by granulysin (show GNLY ELISA Kits) and perforin (show PRF1 ELISA Kits), granzymes generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  10. Results reveal enhanced intra- and extracellular expression of gzmA (show GZMA ELISA Kits) and B in patients with pulmonary TB, suggesting that gzms are part of the host response to tuberculosis.

Cow (Bovine) Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) interaction partners

  1. It is a cytotoxic genes in the endometrium and hightly expressed in the peri (show PLIN1 ELISA Kits)-implantation endometrium.

GZMB (Gzmb) Antigen Profile

Antigen Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Alternative names and synonyms associated with GZMB (Gzmb)

  • granzyme B (GZMB) Elisa Kit
  • granzyme B (Gzmb) Elisa Kit
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) Elisa Kit
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (Gzmb) Elisa Kit
  • AI553453 Elisa Kit
  • BDMD1 Elisa Kit
  • CCP-1/C11 Elisa Kit
  • CCP1 Elisa Kit
  • CCPI Elisa Kit
  • CGL-1 Elisa Kit
  • CGL1 Elisa Kit
  • CSP-B Elisa Kit
  • CSPB Elisa Kit
  • Ctla-1 Elisa Kit
  • CTLA1 Elisa Kit
  • CTSGL1 Elisa Kit
  • GZB Elisa Kit
  • GZMB Elisa Kit
  • GZMH Elisa Kit
  • HLP Elisa Kit
  • RNKP-1 Elisa Kit
  • SECT Elisa Kit

Protein level used designations for Gzmb

granzyme B , cytotoxic cell protease 1 , fragmentin-2 , granzyme B(G,H) , C11 , CTLA-1 , T-cell serine protease 1-3E , cathepsin G-like 1 , cytotoxic T-lymphocyte proteinase 2 , cytotoxic serine protease B , fragmentin 2 , human lymphocyte protein , GLP I , GLP III , GLP-1 , fragmentin , granzyme-like protein 1 , granzyme-like protein I , natural killer cell protease 1 , granzyme H , duodenase I , duodenase-1 , duodenum serine protease

GENE ID SPECIES
100127106 Felis catus
14939 Mus musculus
3002 Homo sapiens
171528 Rattus norvegicus
452825 Pan troglodytes
716518 Macaca mulatta
100233184 Sus scrofa
508646 Bos taurus
281731 Bos taurus
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