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Browse our KRT18 Proteins (KRT18)

Full name:
Keratin 18 Proteins (KRT18)
On are 44 Keratin 18 (KRT18) Proteins from 11 different suppliers available. Additionally we are shipping KRT18 Antibodies (968) and KRT18 Kits (54) and many more products for this protein. A total of 1083 KRT18 products are currently listed.
cb83, CK18, CYK18, dapk1, DreK18, K18, Krt1-18, KRT18, krtt1c6, MGC64569, MGC75922, sb:cb83, wu:fa13f02, wu:fb36b04, zgc:66015
list all proteins Gene Name GeneID UniProt
KRT18 3875 P05783
KRT18 16668 P05784
KRT18 294853 Q5BJY9

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KRT18 Proteins (KRT18) by Origin

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More Proteins for KRT18 Interaction Partners

Human Keratin 18 (KRT18) interaction partners

  1. Serum concentrations of CK-18 fragments and transgelin-2 correlate with the severity of NAFLD, but not with obesity.

  2. High KRT18 serum levels are associated with non-small-cell lung cancer.

  3. Serum HGF (show HGF Proteins) and CK18 levels were significantly up-regulated and positively correlated with metastasis stage, tumor stage, and disease stage of esophageal squamous cell carcinoma.

  4. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63 (show RPE65 Proteins), and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

  5. CK18 plays an important role in lung cancer progression and may be a therapeutic target for non small cell lung cancer.

  6. Data show that after siRNA transfection, TGF-beta1 (show TGFB1 Proteins) protein level was decreased, and CK18 proteins was decreased, while CK8 (show KRT8 Proteins) proteins was increased, and TERT (show TERT Proteins) protein expression was slightly increased at 96 h.

  7. these results suggest that cytokeratin 18 critically contributes to initiating TGF-beta1 (show TGFB1 Proteins)-induced EMT (show ITK Proteins) via the smad 2 (show SMAD2 Proteins)/3-mediated regulation of snail (show SNAI1 Proteins) and slug (show SNAI2 Proteins) expression in breast epithelial cells.

  8. The interplay between Solo protein and keratin 8/keratin 18 filaments plays a crucial role in tensile force-induced RhoA activation and consequent actin cytoskeletal reinforcement in endothelial cells.

  9. Study demonstrated that the downregulation of CK18 is associated with the acquisition of paclitaxel-resistance and tumor aggressiveness in prostate cancer.

  10. Data indicate that O-GlcNAcylation at serine Ser30 determines the occurrence of Pposphorylation at Ser33 on Keratin 18 (K18).

Cow (Bovine) Keratin 18 (KRT18) interaction partners

  1. Ezrin (show EZR Proteins) and CK18 are downregulated during implantation in cattle. The expression changes represent a temporal depolarization, which could be important for an establishment of bovine pregnancy.

  2. Results did not support that K8/K18 filaments influence the expression of Fas (show FAS Proteins) on the surface of luteal cells.

  3. Data indicate that CK18 may be a molecular marker for bovine M cells in follicule-associated epithelium of Peyer's patches.

  4. KRT18 knockdown in preimplantation embryos results in reduced blastocyst formation, but no further morphological aberrations were observed with regard to the biological function of KRT18.

Mouse (Murine) Keratin 18 (KRT18) interaction partners

  1. autoantibodies were detected in aging K18-null male mice that had a related liver phenotype but normal colon compared with K8-null mice, suggesting that the autoantibodies are linked to liver rather than colonic disease

  2. In human failing myocardium, where TNF-alpha (show TNF Proteins) expression is upregulated, K8/K18 were also ectopically expressed

  3. The findings demonstrate the near complete loss of K8/K18 with concomitant high levels of vimentin (show VIM Proteins) in CT26 (show DDX53 Proteins) cells, a chemically-induced mouse colonic tumor.

  4. in contrast to its importance as luminal cell marker, CK18 is dispensable for the prostate morphogenesis but contributes to adult prostate regeneration

  5. Keratin 18 increases CFTR (show CFTR Proteins) expression by binding to its C-terminal hydrophobic domain.

  6. Oxidative stress, Nrf2 (show NFE2L2 Proteins) and keratin 18 up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria (show FECH Proteins)

  7. Keratin 8 (show KRT8 Proteins) and keratin 18 mice on the same genetic background show similar sensitivity to DDC (show DDC Proteins) intoxication.

  8. These findings reveal the potential for cytokeratin 18 to be used as a diagnostic marker for early detection of hepatosplenic schistosomiasis.

  9. K18 glycosylation provides a unique protective role in epithelial injury by promoting the phosphorylation and activation of cell-survival kinases.

  10. Krt18 may be a useful immunohistochemical marker for detecting hepatocellular proliferative lesions in mice.

Zebrafish Keratin 18 (KRT18) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

  2. krt18 is maternally inherited and its tissue distribution is reported. Its expression is established during early embryogenesis.

Pig (Porcine) Keratin 18 (KRT18) interaction partners

  1. Mechanical injury of vascular smooth muscle up-regulated keratin 18.

KRT18 Protein Profile

Protein Summary

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with KRT18

  • keratin 18 (krt18)
  • similar to Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (KRT18)
  • keratin 18 (KRT18)
  • Keratin, type I cytoskeletal 18 (k1c18)
  • cytokeratin 18 (LOC100008885)
  • K18, simple type I keratin (LOC100136778)
  • keratin 18 (Krt18)
  • zgc:77517 (zgc:77517)
  • cb83 protein
  • CK18 protein
  • CYK18 protein
  • dapk1 protein
  • DreK18 protein
  • K18 protein
  • Krt1-18 protein
  • KRT18 protein
  • krtt1c6 protein
  • MGC64569 protein
  • MGC75922 protein
  • sb:cb83 protein
  • wu:fa13f02 protein
  • wu:fb36b04 protein
  • zgc:66015 protein

Protein level used designations for Keratin 18 Proteins (KRT18)

keratin 18 , Keratin, type I cytoskeletal 18 , keratin, type I cytoskeletal 18-like , CK-18 , cytokeratin-18 , keratin, type I cytoskeletal 18 , keratin-18 , simple type I keratin , cell proliferation-inducing gene 46 protein , cell proliferation-inducing protein 46 , cytokeratin 18 , Endo B , cytokeratin endo B , keratin D , keratin complex 1, acidic, gene 18 , K18 , dorsal aorta proneprin kinesin-1 , keratin 18-like , keratin-like

380504 Xenopus laevis
394541 Xenopus (Silurana) tropicalis
693413 Macaca mulatta
700110 Macaca mulatta
700569 Macaca mulatta
704517 Macaca mulatta
705090 Macaca mulatta
712908 Macaca mulatta
100195474 Salmo salar
100400783 Callithrix jacchus
100462638 Pongo abelii
451923 Pan troglodytes
100008885 Oryctolagus cuniculus
100136778 Oncorhynchus mykiss
3875 Homo sapiens
506480 Bos taurus
16668 Mus musculus
294853 Rattus norvegicus
352912 Danio rerio
734797 Xenopus laevis
100126286 Sus scrofa
393540 Danio rerio
477601 Canis lupus familiaris
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