Browse our anti-Lamin A/C (LMNA) Antibodies

Full name:
anti-Lamin A/C Antibodies (LMNA)
On www.antibodies-online.com are 406 Lamin A/C (LMNA) Antibodies from 35 different suppliers available. Additionally we are shipping Lamin A/C Kits (26) and Lamin A/C Proteins (15) and many more products for this protein. A total of 464 Lamin A/C products are currently listed.
Synonyms:
74/76, 2459, cb948, CDCD1, CDDC, CG6944, CMD1A, CMT2B1, D5, Dhe, Dm, Dm(0), Dm0, Dm1, Dm2, Dmel\\CG6944, DmLamin, Dmo, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], Dm[[o]], EMD2, fk66d12, FPL, FPLD, FPLD2, HGPS, IDC, jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, lam, Lam(Dm0), lamDm0, lamDm[[0]], Lam Dm[[0]], LamDm[[o]], lamin, Lamin-A, lamin-L(III)-like, lamin Dm0, lamin Dm[[0]], Lam[[Dm0]], LDP1, LFP, LGMD1B, LMN1, lmna-A, LMNC, LMNL1, misg, nlam, PRO1, wu:fk66d12

Most Popular Reactivities for anti-Lamin A/C (LMNA) Antibodies

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anti-Mouse (Murine) Lamin A/C Antibodies:

anti-Human Lamin A/C Antibodies:

anti-Rat (Rattus) Lamin A/C Antibodies:

All available anti-Lamin A/C Antibodies

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Top referenced anti-Lamin A/C Antibodies

  1. Cow (Bovine) Monoclonal Lamin A/C Primary Antibody for FACS, IHC (fro) - ABIN112042 : Machiels, Broers, Raymond, de Ley, Kuijpers, Caberg, Ramaekers: Abnormal A-type lamin organization in a human lung carcinoma cell line. in European journal of cell biology 1996 (PubMed)
    Show all 12 references for 112042

  2. Cow (Bovine) Monoclonal Lamin A/C Primary Antibody for IHC (fro), IF - ABIN400876 : SAUER, CHITTENDEN: Deoxyribonucleic acid content of cell nuclei in the neural tube of the chick embryo: evidence for intermitotic migration of nuclei. in Experimental cell research 1959 (PubMed)
    Show all 4 references for 400876

  3. Chicken Monoclonal Lamin A/C Primary Antibody for IF, WB - ABIN968765 : McKeon, Kirschner, Caput: Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. in Nature 1986 (PubMed)
    Show all 3 references for 968765

  4. Hamster Monoclonal Lamin A/C Primary Antibody for ICC, IF - ABIN2668844 : Kim, Zheng: Generation and characterization of a conditional deletion allele for Lmna in mice. in Biochemical and biophysical research communications 2013 (PubMed)
    Show all 3 references for 2668844

  5. Mouse (Murine) Monoclonal Lamin A/C Primary Antibody for FACS, ICC - ABIN108550 : Pugh, Coates, Lane, Raymond, Quinlan: Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells. in Journal of cell science 1997 (PubMed)
    Show all 2 references for 108550

  6. Mouse (Murine) Monoclonal Lamin A/C Primary Antibody for ICC, IF - ABIN108630 : Dyer, Kill, Pugh, Quinlan, Lane, Hutchison: Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies. in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1998 (PubMed)
    Show all 2 references for 108630

  7. Human Polyclonal Lamin A/C Primary Antibody for IF (cc), IF (p) - ABIN735188 : Yi, Pan, Pan, Song, Hu, Wang, Pan, Lu: BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori. in Biochemical and biophysical research communications 2014 (PubMed)

More Antibodies against Lamin A/C Interaction Partners

Fruit Fly (Drosophila melanogaster) Lamin A/C (LMNA) interaction partners

  1. The loss of lamin-B (show LMNB1 Antibodies) leads to systemic inflammation and aging.

  2. nuclear Wash interacts with B-type Lamin (Lamin Dm0), and, like Lamin, Wash associates with constitutive heterochromatin

  3. of single phosphorylation sites of Drosophila melanogaster lamin Dm and lamin C

  4. Rab5 (show RAB5A Antibodies) associated in vivo with nuclear Lamin and mushroom body defect (Mud (show AP5M1 Antibodies)), the Drosophila counterpart of nuclear mitotic apparatus protein (NuMA (show NUMA1 Antibodies)).

  5. Kugelkern and lamin Dm0 affect nuclear shape without requiring filament formation or the presence of a classical nuclear lamina.

  6. Lamin mutation is associated with neuromuscular defects and premature aging.

  7. prometaphase spindle can be made robust to natural fluctuations in motor ratios by a disassembling lamin-B (show LMNB1 Antibodies) envelope.

  8. Molecular interactions with lamin Dm0 may link JIL-1 kinase to nuclear morphology and integrity of nurse cells during oogenesis.

  9. The lamin Dm0 allele Ari3 acts as an enhancer of position effect variegation of the wm4 allele in Drosophila.

  10. Both lamin Dm0 and C. elegans Ce-lamin bind directly to histone H2A in vitro and this binding requires the nuclear localization signal

Zebrafish Lamin A/C (LMNA) interaction partners

  1. results have important implications for understanding the tissue-specific regulation and functions of the lamin A gene

  2. The induction of embryonic senescence and laminopathies in zebrafish harboring disturbed expressions of the lamin A gene, is described.

Mouse (Murine) Lamin A/C (LMNA) interaction partners

  1. Activation of WNT/b-catenin activity improved cardiac contractility and ameliorated intraventricular conduction defects in LmnaH222P/H222P mice, which was associated with increased expression of myocardial connexin 43. These results indicate that decreased WNT/b-catenin contributes to the pathophysiology of LMNA cardiomyopathy and that drugs activating b-catenin may be beneficial in affected individuals

  2. SUMO1 (show SUMO1 Antibodies) conjugation of RB and Lamin A/C is modulated by the SUMO protease SENP1 (show SENP1 Antibodies) and that sumoylation of both proteins is required for their interaction.

  3. Lmna-deficient cells show a compromised strain avoidance response, which is completely abolished when topographical cues and uniaxial strain are applied along the same direction.

  4. While the distribution patterns of both lamins closely paralleled the respective stages of mitosis, Nup160 (show NUP160 Antibodies) localization in metaphase oocytes corresponded to that in mitotic prometaphase rather than metaphase.

  5. changes in nuclear size and shape, which are mediated by nuclear envelope structural proteins lamin A/C and/or emerin (show EMD Antibodies), also impact gene regulation and lineage differentiation in early embryos.

  6. administration of the exon 11 ASO reduced lamin A expression in wild-type mice and progerin expression in an HGPS mouse model.

  7. stabilization of perinuclear actin strengthens the transient interactions of lamin A with chromatin

  8. It was found that the lamin A protein expressed in mouse ear cartilage cells is shorter than protein expressed in mouse skin. This difference in protein length could be caused by differential cleavage in the cells of skin and ear cartilage tissues

  9. Annexin, lamin, and vimentin (show VIM Antibodies) were identified as universal dystrophic markers

  10. These results identify SNX6 (show SNX6 Antibodies) as a key regulator of lamin A synthesis and incorporation into the nuclear envelope.

Human Lamin A/C (LMNA) interaction partners

  1. Pathogenic variants of the LMNA gene were determined in nine families with familial partial lipodystrophy

  2. The interaction of progerin with lamin A/C contributes to the development of the senescence phenotype of Hutchinson-Gilford progeria syndrome and aged cells.

  3. we expressed a LEMD2 transgene alone or in combination with lamin C in these cells and observed no restoration of peripheral heterochromatin in either case. We conclude that in contrary to the B-tether, the A-tether has a more intricate composition and consists of multiple components that presumably vary, at differing degrees of redundancy, between cell types and differentiation stages

  4. These abnormalities are associated with increased transforming growth factor-b (show ATP5S Antibodies) signaling and defects in matrix metalloproteinase 9 (show MMP9 Antibodies) activity. Our data demonstrate that lamin A/C gene mutations responsible for FPLD2 and related lipodystrophies are associated with transforming growth factor-beta activation

  5. Case Report: identical twin brothers with same lamin A/C missense mutation where one developed dilated cardiomyopathy/heart failure and the other remained asymptomatic.

  6. p.S143P lamin A/C affects normal lamina structure and influences the cellular stress response, homeostasis and viability.

  7. This case demonstrates that accumulation of prelamin A, independent of the loss of function of ZMPSTE24 (show Zmpste24 Antibodies) metallopeptidase (show ECEL1 Antibodies) that catalyzes processing of prelamin A, can cause a progeroid disorder and that a cell biology assay could be used in precision medicine to identify a potential therapy.

  8. A novel homozygous LMNA missense variant identified in a patient presenting poikiloderma, joint stiffness and distal acroosteolysis without features of muscle weakness.

  9. c.1824C>T remains the most frequent mutation in Hutchinson-Gilford Progeria Syndrome patients, other mutations in the LMNA gene have been reported that result in increased usage of the cryptic splice site.

  10. We present a female patient with a unique phenotype including rare atypical progeroid syndrome and dilated cardiomyopathy. Genetic mutation detection in the gene LMNA revealed a novel heterozygous de novo mutation p.Leu59Val located in the first exon of gene LMNA c.175C>CG.

Pig (Porcine) Lamin A/C (LMNA) interaction partners

  1. Both anti-lamin A/C and anti-lamin B (show LMNB1 Antibodies) staining were clearly present in all embryonic stages.

  2. A study mapping the location of procine lamin type A to chromosome 4q is presented.

Xenopus laevis Lamin A/C (LMNA) interaction partners

  1. These results indicate that thyroid hormone (show PTH Antibodies)-regulated expression of nuclear lamin A and LIII closely correlates with dedifferentiation of the epithelial cells in the X. laevis intestine.

  2. LIII filaments appear identical to the endogenous lamina, whereas lamin B2 (show LMNB2 Antibodies) assembles into filaments that are organized less precisely; Lamin A induces sheets of thicker filaments on the endogenous lamina and increases the rigidity of the nuclear envelope

Lamin A/C (LMNA) Antigen Profile

Antigen Summary

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Alternative names and synonyms associated with Lamin A/C (LMNA)

  • Lamin (Lam) antibody
  • lamin A (lmna) antibody
  • lamin A/C (LMNA) antibody
  • lamin B3 (lmnb3) antibody
  • lamin A/C (lmna) antibody
  • lamin A (Lmna) antibody
  • lamin A/C (Lmna) antibody
  • 74/76 antibody
  • 2459 antibody
  • cb948 antibody
  • CDCD1 antibody
  • CDDC antibody
  • CG6944 antibody
  • CMD1A antibody
  • CMT2B1 antibody
  • D5 antibody
  • Dhe antibody
  • Dm antibody
  • Dm(0) antibody
  • Dm0 antibody
  • Dm1 antibody
  • Dm2 antibody
  • Dmel\\CG6944 antibody
  • DmLamin antibody
  • Dmo antibody
  • Dm[[0]] antibody
  • Dm[[1]] antibody
  • Dm[[2]] antibody
  • Dm[[mit]] antibody
  • Dm[[o]] antibody
  • EMD2 antibody
  • fk66d12 antibody
  • FPL antibody
  • FPLD antibody
  • FPLD2 antibody
  • HGPS antibody
  • IDC antibody
  • jf27 antibody
  • l(2)04643 antibody
  • l(2)25Ec antibody
  • l(2)gdh-7 antibody
  • l(2)gdh7 antibody
  • l(2)jf27 antibody
  • lam antibody
  • Lam(Dm0) antibody
  • lamDm0 antibody
  • lamDm[[0]] antibody
  • Lam Dm[[0]] antibody
  • LamDm[[o]] antibody
  • lamin antibody
  • Lamin-A antibody
  • lamin-L(III)-like antibody
  • lamin Dm0 antibody
  • lamin Dm[[0]] antibody
  • Lam[[Dm0]] antibody
  • LDP1 antibody
  • LFP antibody
  • LGMD1B antibody
  • LMN1 antibody
  • lmna-A antibody
  • LMNC antibody
  • LMNL1 antibody
  • misg antibody
  • nlam antibody
  • PRO1 antibody
  • wu:fk66d12 antibody

Protein level used designations for anti-Lamin A/C (LMNA) Antibodies

B-type lamin , CG6944-PA , CG6944-PB , CG6944-PC , Lam-PA , Lam-PB , Lam-PC , Lamin-B , LaminDm , LaminDm0 , alpha-Lamin , intermediate filament-like lamina , lamin , lamin A , lamin B , lamin D , lamin D[[0]] , lamin D[[m]]0 , lamin D[[o]] , lamin Dm0 , lamin Dm[[0]] , lamin Dmo , lethal(2)25Ec , misguided , misrouted , n-lamin , nuclear lamin , prelamin-A/C , lamin B3 , lamin A/C , lamin LIII , lamin-A/C-like , lamin C , lamin-A/C , 70 kDa lamin , lamin A/C-like 1 , renal carcinoma antigen NY-REN-32 , lamin C2 , lamin-A

GENE ID SPECIES
33782 Drosophila melanogaster
195815 Danio rerio
457385 Pan troglodytes
719414 Macaca mulatta
733537 Xenopus (Silurana) tropicalis
733973 Xenopus (Silurana) tropicalis
100401580 Callithrix jacchus
100603145 Nomascus leucogenys
16905 Mus musculus
4000 Homo sapiens
60374 Rattus norvegicus
480124 Canis lupus familiaris
404144 Bos taurus
101107924 Ovis aries
100126859 Sus scrofa
373673 Xenopus laevis
415464 Gallus gallus
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