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Browse our anti-Lamin A/C (LMNA) Antibodies

Full name:
anti-Lamin A/C Antibodies (LMNA)
On www.antibodies-online.com are 416 Lamin A/C (LMNA) Antibodies from 34 different suppliers available. Additionally we are shipping Lamin A/C Kits (22) and Lamin A/C Proteins (10) and many more products for this protein. A total of 465 Lamin A/C products are currently listed.
Synonyms:
74/76, 2459, cb948, CDCD1, CDDC, CG6944, CMD1A, CMT2B1, D5, Dhe, Dm, Dm(0), Dm0, Dm1, Dm2, Dmel\\CG6944, DmLamin, Dmo, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], Dm[[o]], EMD2, fk66d12, FPL, FPLD, FPLD2, HGPS, IDC, jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, lam, Lam(Dm0), lamDm0, lamDm[[0]], Lam Dm[[0]], LamDm[[o]], lamin, Lamin-A, lamin-L(III)-like, lamin Dm0, lamin Dm[[0]], Lam[[Dm0]], LDP1, LFP, LGMD1B, LMN1, lmna-A, LMNC, LMNL1, misg, nlam, PRO1, wu:fk66d12

Most Popular Reactivities for anti-Lamin A/C (LMNA) Antibodies

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anti-Mouse (Murine) Lamin A/C Antibodies:

anti-Human Lamin A/C Antibodies:

anti-Rat (Rattus) Lamin A/C Antibodies:

All available anti-Lamin A/C Antibodies

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Top referenced anti-Lamin A/C Antibodies

  1. Cow (Bovine) Monoclonal Lamin A/C Primary Antibody for FACS, IHC (fro) - ABIN112042 : Machiels, Broers, Raymond, de Ley, Kuijpers, Caberg, Ramaekers: Abnormal A-type lamin organization in a human lung carcinoma cell line. in European journal of cell biology 1996 (PubMed)
    Show all 12 references for ABIN112042

  2. Cow (Bovine) Monoclonal Lamin A/C Primary Antibody for IHC (fro), IF - ABIN400876 : SAUER, CHITTENDEN: Deoxyribonucleic acid content of cell nuclei in the neural tube of the chick embryo: evidence for intermitotic migration of nuclei. in Experimental cell research 1959 (PubMed)
    Show all 4 references for ABIN400876

  3. Chicken Monoclonal Lamin A/C Primary Antibody for IF, WB - ABIN968765 : McKeon, Kirschner, Caput: Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. in Nature 1986 (PubMed)
    Show all 3 references for ABIN968765

  4. Mouse (Murine) Monoclonal Lamin A/C Primary Antibody for ICC, IF - ABIN108630 : Dyer, Kill, Pugh, Quinlan, Lane, Hutchison: Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies. in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1998 (PubMed)
    Show all 2 references for ABIN108630

  5. Mouse (Murine) Monoclonal Lamin A/C Primary Antibody for ICC, IF - ABIN108629 : Mota, Mendes, Freitas, Penque, Coelho, Cunha: Proteome analysis of a human liver carcinoma cell line stably expressing hepatitis delta virus ribonucleoproteins. in Journal of proteomics 2009 (PubMed)
    Show all 2 references for ABIN108629

  6. Hamster Monoclonal Lamin A/C Primary Antibody for ICC, IF - ABIN2668844 : Kim, Zheng: Generation and characterization of a conditional deletion allele for Lmna in mice. in Biochemical and biophysical research communications 2013 (PubMed)
    Show all 2 references for ABIN2668844

  7. Mouse (Murine) Monoclonal Lamin A/C Primary Antibody for FACS, ICC - ABIN108550 : Pugh, Coates, Lane, Raymond, Quinlan: Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells. in Journal of cell science 1997 (PubMed)
    Show all 2 references for ABIN108550

More Antibodies against Lamin A/C Interaction Partners

Fruit Fly (Drosophila melanogaster) Lamin A/C (LMNA) interaction partners

  1. The loss of lamin-B (show LMNB1 Antibodies) leads to systemic inflammation and aging.

  2. nuclear Wash interacts with B-type Lamin (Lamin Dm0), and, like Lamin, Wash associates with constitutive heterochromatin

  3. of single phosphorylation sites of Drosophila melanogaster lamin Dm and lamin C

  4. Rab5 (show RAB5A Antibodies) associated in vivo with nuclear Lamin and mushroom body defect (Mud (show AP5M1 Antibodies)), the Drosophila counterpart of nuclear mitotic apparatus protein (NuMA (show NUMA1 Antibodies)).

  5. Kugelkern and lamin Dm0 affect nuclear shape without requiring filament formation or the presence of a classical nuclear lamina.

  6. Lamin mutation is associated with neuromuscular defects and premature aging.

  7. prometaphase spindle can be made robust to natural fluctuations in motor ratios by a disassembling lamin-B (show LMNB1 Antibodies) envelope.

  8. Molecular interactions with lamin Dm0 may link JIL-1 kinase to nuclear morphology and integrity of nurse cells during oogenesis.

  9. The lamin Dm0 allele Ari3 acts as an enhancer of position effect variegation of the wm4 allele in Drosophila.

  10. Both lamin Dm0 and C. elegans Ce-lamin bind directly to histone H2A in vitro and this binding requires the nuclear localization signal

Zebrafish Lamin A/C (LMNA) interaction partners

  1. results have important implications for understanding the tissue-specific regulation and functions of the lamin A gene

  2. The induction of embryonic senescence and laminopathies in zebrafish harboring disturbed expressions of the lamin A gene, is described.

Mouse (Murine) Lamin A/C (LMNA) interaction partners

  1. administration of the exon 11 ASO reduced lamin A expression in wild-type mice and progerin expression in an HGPS mouse model.

  2. stabilization of perinuclear actin strengthens the transient interactions of lamin A with chromatin

  3. It was found that the lamin A protein expressed in mouse ear cartilage cells is shorter than protein expressed in mouse skin. This difference in protein length could be caused by differential cleavage in the cells of skin and ear cartilage tissues

  4. Annexin, lamin, and vimentin (show VIM Antibodies) were identified as universal dystrophic markers

  5. These results identify SNX6 (show SNX6 Antibodies) as a key regulator of lamin A synthesis and incorporation into the nuclear envelope.

  6. loss of Lmna under malignant conditions may, to a limited extent, enhance polyp size indicating that A-type lamins may regulate cell proliferation in the transformed GI epithelium

  7. The results presented in this work indicate that the detrimental effects of lamin A expression were less than anticipated in the brain, even after 90 weeks of transgenic expression.

  8. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

  9. Results suggest that lamin A/C is critical for proper structural and functional development of the sperm acrosome and head shape.

  10. progerin and p16(INK4a (show CDKN2A Antibodies)) expression, beta-galactosidase (show GLB1 Antibodies) activity, and reactive oxygen species, which increase with age, were higher in young Xpc (show XPC Antibodies)(-/-) mice than in young Xpc (show XPC Antibodies)(+/+) ones

Human Lamin A/C (LMNA) interaction partners

  1. Variant c.513+45T>G in the LMNA gene is new intronic splicing mutation which is responsible for progressive cardiac conduction defects and variable myopathy.

  2. Cardiac involvement as a consequence of LMNA mutations generally has a more aggressive natural history than other forms of non-ischemic dilated cardiomyopathy. A high index of suspicion and prompt referral for genetic testing are essential for appropriate therapeutic management

  3. Although it is previously known that alterations in the rod domain of type A lamins are involved in cardiac and neuromuscular diseases, the current observation shows that exon 1 LMNA mutations may be associated with partial lipodystrophy without any cardiac and neurological abnormalities, at least at the time of the presentation.

  4. the Lamin C : Lamin A mRNA ratio is increased in breast cancer.

  5. Two siblings who presented with generalized lipodystrophy were diagnosed with an atypical progeroid syndrome with a p.D136H mutation in the LMNA gene (NM_005572). We diagnosed a familial atypical progeroid syndrome using whole genome sequencing.

  6. A case of laminopathy associated with dilated cardiomyopathy, lipodystrophy and mandibular dysplasia was linked to a mutation in the LMNA gene.

  7. discuss a model of progeria where faulty serine 22 phosphorylation compromises phase separation of lamin A polymers, leading to accumulation of functionally impaired lamin A structures

  8. A novel LMNA mutation was identified in a patient with cardiomyopathy and arrhythmia and a family history of bradyarrhythmia.

  9. ZMPSTE24 (show Zmpste24 Antibodies) downregulation is a major contributor in VSMC dysfunctions resulting from LMNA mutations or PI treatments that could translate in early atherosclerosis at the clinical level.

  10. Lamin A/C deficiency may serve as an independent risk factor for cervical intra-epithelial neoplasia development and as an indicator for preventive therapy in cervical cancer.

Pig (Porcine) Lamin A/C (LMNA) interaction partners

  1. Both anti-lamin A/C and anti-lamin B (show LMNB1 Antibodies) staining were clearly present in all embryonic stages.

  2. A study mapping the location of procine lamin type A to chromosome 4q is presented.

Xenopus laevis Lamin A/C (LMNA) interaction partners

  1. These results indicate that thyroid hormone (show PTH Antibodies)-regulated expression of nuclear lamin A and LIII closely correlates with dedifferentiation of the epithelial cells in the X. laevis intestine.

  2. LIII filaments appear identical to the endogenous lamina, whereas lamin B2 (show LMNB2 Antibodies) assembles into filaments that are organized less precisely; Lamin A induces sheets of thicker filaments on the endogenous lamina and increases the rigidity of the nuclear envelope

Lamin A/C (LMNA) Antigen Profile

Antigen Summary

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Alternative names and synonyms associated with Lamin A/C (LMNA)

  • Lamin (Lam) antibody
  • lamin A (lmna) antibody
  • lamin A/C (LMNA) antibody
  • lamin B3 (lmnb3) antibody
  • lamin A/C (lmna) antibody
  • lamin A (Lmna) antibody
  • lamin A/C (Lmna) antibody
  • 74/76 antibody
  • 2459 antibody
  • cb948 antibody
  • CDCD1 antibody
  • CDDC antibody
  • CG6944 antibody
  • CMD1A antibody
  • CMT2B1 antibody
  • D5 antibody
  • Dhe antibody
  • Dm antibody
  • Dm(0) antibody
  • Dm0 antibody
  • Dm1 antibody
  • Dm2 antibody
  • Dmel\\CG6944 antibody
  • DmLamin antibody
  • Dmo antibody
  • Dm[[0]] antibody
  • Dm[[1]] antibody
  • Dm[[2]] antibody
  • Dm[[mit]] antibody
  • Dm[[o]] antibody
  • EMD2 antibody
  • fk66d12 antibody
  • FPL antibody
  • FPLD antibody
  • FPLD2 antibody
  • HGPS antibody
  • IDC antibody
  • jf27 antibody
  • l(2)04643 antibody
  • l(2)25Ec antibody
  • l(2)gdh-7 antibody
  • l(2)gdh7 antibody
  • l(2)jf27 antibody
  • lam antibody
  • Lam(Dm0) antibody
  • lamDm0 antibody
  • lamDm[[0]] antibody
  • Lam Dm[[0]] antibody
  • LamDm[[o]] antibody
  • lamin antibody
  • Lamin-A antibody
  • lamin-L(III)-like antibody
  • lamin Dm0 antibody
  • lamin Dm[[0]] antibody
  • Lam[[Dm0]] antibody
  • LDP1 antibody
  • LFP antibody
  • LGMD1B antibody
  • LMN1 antibody
  • lmna-A antibody
  • LMNC antibody
  • LMNL1 antibody
  • misg antibody
  • nlam antibody
  • PRO1 antibody
  • wu:fk66d12 antibody

Protein level used designations for anti-Lamin A/C (LMNA) Antibodies

B-type lamin , CG6944-PA , CG6944-PB , CG6944-PC , Lam-PA , Lam-PB , Lam-PC , Lamin-B , LaminDm , LaminDm0 , alpha-Lamin , intermediate filament-like lamina , lamin , lamin A , lamin B , lamin D , lamin D[[0]] , lamin D[[m]]0 , lamin D[[o]] , lamin Dm0 , lamin Dm[[0]] , lamin Dmo , lethal(2)25Ec , misguided , misrouted , n-lamin , nuclear lamin , prelamin-A/C , lamin B3 , lamin A/C , lamin LIII , lamin-A/C-like , lamin C , lamin-A/C , 70 kDa lamin , lamin A/C-like 1 , renal carcinoma antigen NY-REN-32 , lamin C2 , lamin-A

GENE ID SPECIES
33782 Drosophila melanogaster
195815 Danio rerio
457385 Pan troglodytes
719414 Macaca mulatta
733537 Xenopus (Silurana) tropicalis
733973 Xenopus (Silurana) tropicalis
100401580 Callithrix jacchus
100603145 Nomascus leucogenys
16905 Mus musculus
4000 Homo sapiens
60374 Rattus norvegicus
480124 Canis lupus familiaris
404144 Bos taurus
101107924 Ovis aries
100126859 Sus scrofa
373673 Xenopus laevis
415464 Gallus gallus
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