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anti-Dog (Canine) Lamin A/C antibody for Western Blotting

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • Dhe
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • lmna-A
  • lamin-L(III)-like
  • Lamin
  • lamin A
  • lamin A/C
  • lamin B3
  • Lam
  • lmna
  • LMNA
  • lmnb3
  • Lmna
Epitope
AA 398-490
25
24
24
19
19
15
15
13
9
9
8
7
6
4
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
385
213
197
86
43
40
19
16
10
10
5
3
3
3
2
1
1
1
1
Host
Mouse
220
171
5
1
Clonality
Monoclonal
Conjugate
This Lamin A/C antibody is un-conjugated
10
8
8
6
6
6
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
334
161
129
127
102
65
64
59
43
27
11
2
2
2
1
1
Options
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Catalog No. ABIN968765
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0238638 ABIN968766 IF WB Mouse IgG1 AA 398-490 Log in to see 14-LaminAC 3
3.0238638 ABIN4330009 CyTOF FACS ICC IF IHC IHC (fro) WB Mouse IgG1 AA 319-566 Log in to see 131C3
1 ABIN112042 FACS IHC (fro) IF IHC (p) WB Mouse IgG3 Log in to see 133A2 12
1 ABIN108550 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG3 kappa AA 598-611 Log in to see 133A2 2
1 ABIN112346 FACS IHC (fro) IF WB Mouse IgG1 Log in to see 131C3 3
1 ABIN335242 ICC FACS IHC (fro) IHC WB Mouse IgG3 Log in to see 133A2 10
1 ABIN4329985 CyTOF FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN335389 ICC FACS IHC (fro) IHC WB Mouse IgG3 Log in to see 133A2 10
1 ABIN335243 ICC FACS IHC (fro) IHC WB Mouse IgG1 Log in to see 131C3 3
1 ABIN4329986 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN335390 ICC FACS IHC (fro) IHC WB Mouse IgG1 Log in to see 131C3 3
1 ABIN2469601 IHC WB Rabbit IgG AA 249-266 Log in to see Polyclonal
1 ABIN4329994 ICC IF IHC IHC (fro) WB Biotin Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4329997 FACS ICC IF IHC IHC (fro) WB DyLight 680 Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4329990 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 488 Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4329989 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 405 Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4330001 FACS ICC IF IHC (fro) WB PerCP Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4330004 FACS ICC IF IHC IHC (fro) WB DyLight 350 Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4329995 FACS ICC IF IHC IHC (fro) WB DyLight 650 Mouse IgG3 AA 598-611 Log in to see 133A2
1 ABIN4329991 FACS ICC IF IHC IHC (fro) WB Alexa Fluor 647 Mouse IgG3 AA 598-611 Log in to see 133A2

Top referenced anti-Lamin A/C antibody for Western Blotting

Similar anti-Lamin A/C Antibodies

Application / Reactivity Dog (Canine) Human Mouse (Murine) Rat (Rattus) Chicken
Cytometry by Time of Flight (CyTOF) 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 170 Antibodies 157 Antibodies 323 Antibodies 39 Antibodies 3 Antibodies
Immunoprecipitation (IP) 43 Antibodies 11 Antibodies 7 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies 63 Antibodies 37 Antibodies 30 Antibodies

General

Antigen Lamin A/C (LMNA) Antibodies
Epitope AA 398-490
(25), (24), (24), (19), (19), (15), (15), (13), (9), (9), (8), (7), (6), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(385), (213), (197), (86), (43), (40), (19), (16), (10), (10), (5), (3), (3), (3), (2), (1), (1), (1), (1)
Host Mouse
(220), (171), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Lamin A/C antibody is un-conjugated
(10), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(334), (161), (129), (127), (102), (65), (64), (59), (43), (27), (11), (2), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C Antibody (ABIN968765) Images
Cross-Reactivity Human, Chicken, Dog (Canine), Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Lamin A/C aa. 398-490
Clone 14-LaminAC
Isotype IgG1

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling References for anti-Lamin A/C Antibody (ABIN968765) Images back to top
Antigen
Alternative Name Lamin A/C (LMNA Antibody Abstract)
Background The nuclear envelope (NE) is a specialized extension of the ER that contains numerous pore complexes interconnected with the nuclear lamina. The nuclear lamina composes the structural framework for the NE and serves as a chromatin anchor site, thus playing a major role in interphase nuclear organization. The major component of nuclear lamina are intermediate filament-like proteins called lamins. In mammalian somatic cells, there are three major lamins, A, B1, and C, and two minor lamins, B2 and A10. A-type lamins (A, A10, and C) are encoded by a single gene and are produced by alternative splicing, while B-type lamins (B1 and B2) are encoded by separate genes. B-type lamins are found in all nucleated somatic cells, while the expression of A-type lamins are developmentally regulated. Mice lacking lamin A show no overt abnormalities until postnatal development when perturbations in nuclear envelop structure correlate with the appearance of muscular dystrophy. In addition, lamin A is mutated in lipodystrophy, a disorder characterized by reduction in subcutaneous adipose tissue. Thus, lamin A and C may be important for nuclear envelope formation during postnatal cell differentiation. This antibody is routinely tested by western blot analysis.
Molecular Weight 65 & 74 kDa
Research Area Cytoskeleton, Extracellular Matrix
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling References for anti-Lamin A/C Antibody (ABIN968765) Images back to top
Comment

Related Products: ABIN968535, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details References for anti-Lamin A/C Antibody (ABIN968765) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-Lamin A/C Antibody (ABIN968765)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Product cited in:

Shackleton, Lloyd, Jackson, Evans, Niermeijer, Singh, Schmidt, Brabant, Kumar, Durrington, Gregory, ORahilly, Trembath: "LMNA, encoding lamin A/C, is mutated in partial lipodystrophy." in: Nature genetics, Vol. 24, Issue 2, pp. 153-6, 2000

Sullivan, Escalante-Alcalde, Bhatt, Anver, Bhat, Nagashima, Stewart, Burke: "Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy." in: The Journal of cell biology, Vol. 147, Issue 5, pp. 913-20, 1999

McKeon, Kirschner, Caput: "Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins." in: Nature, Vol. 319, Issue 6053, pp. 463-8, 1986

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C Antibody (ABIN968765) back to top
Supplier Images
Western Blotting (WB) image for anti-Lamin A/C antibody (LMNA) (AA 398-490) (ABIN968765) Western blot analysis of Lamin A/C on a HeLa lysate. Lane 1: 1:1000, Lane 2: 1:2000, ...