anti-Human Lamin A/C antibody for Immunofluorescence (Cultured Cells)

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • Dhe
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • lmna-A
  • lamin-L(III)-like
  • Lamin
  • lamin A
  • lamin A/C
  • lamin B3
  • Lam
  • lmna
  • LMNA
  • lmnb3
  • Lmna
Reactivity
Human, Mouse (Murine), Rat (Rattus)
407
260
240
103
53
52
22
19
15
10
8
7
5
5
3
3
2
1
1
1
Host
Rabbit
226
180
5
1
Clonality
Polyclonal
Conjugate
This Lamin A/C antibody is un-conjugated
10
8
8
6
6
6
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
364
171
130
129
103
81
65
58
50
26
11
9
2
2
1
Options
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Catalog No. ABIN735188
$ 307.45
Plus shipping costs $45.00

General

Antigen Lamin A/C (LMNA) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(407), (260), (240), (103), (53), (52), (22), (19), (15), (10), (8), (7), (5), (5), (3), (3), (2), (1), (1), (1)
Host Rabbit
(226), (180), (5), (1)
Clonality
Polyclonal
Conjugate This Lamin A/C antibody is un-conjugated
(10), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(364), (171), (130), (129), (103), (81), (65), (58), (50), (26), (11), (9), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C antibody (ABIN735188) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human lamin A
Isotype IgG

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling References for anti-Lamin A/C antibody (ABIN735188) Images back to top
Antigen
Alternative Name Lamin A/C (LMNA Antibody Abstract)
Background

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.

Subcellular location: Nucleus

Synonyms: FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B, Prelamin-A/C, LMNA

Gene ID 4000
UniProt P02545
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling References for anti-Lamin A/C antibody (ABIN735188) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details References for anti-Lamin A/C antibody (ABIN735188) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-Lamin A/C antibody (ABIN735188)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Product cited in:

Yi, Pan, Pan, Song, Hu, Wang, Pan, Lu: "BmICE-2 is a novel pro-apoptotic caspase involved in apoptosis in the silkworm, Bombyx mori." in: Biochemical and biophysical research communications, Vol. 445, Issue 1, pp. 100-6, 2014

Images

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C antibody (ABIN735188) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) antibody (ABIN735188) Formalin-fixed and paraffin embedded human tongue squamous carcinoma cells labeled wi...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) antibody (ABIN735188) Formalin-fixed and paraffin embedded human placenta labeled with Anti-lamin A/C Polyc...