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anti-Sheep (Ovine) Lamin A/C antibody for Immunofluorescence

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • 74/76
  • 2459
  • cb948
  • cdcd1
  • CDCD1
  • CDDC
  • cddc
  • CG6944
  • CMD1A
  • cmd1a
  • cmt2b1
  • CMT2B1
  • D5
  • Dhe
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • Dmel\\CG6944
  • DmLamin
  • DmO
  • Dmo
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • DM[[O]]
  • Dm[[o]]
  • emd2
  • EMD2
  • fk66d12
  • FPL
  • fpl
  • fpld
  • FPLD
  • FPLD2
  • HGPS
  • hgps
  • idc
  • IDC
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • LAM
  • lam
  • Lam(Dm0)
  • lamDm0
  • LamDm[[0]]
  • lamDm[[0]]
  • Lam Dm[[0]]
  • LamDm[[o]]
  • lamin
  • Lamin-A
  • lamin-L(III)-like
  • lamin Dm0
  • lamin Dm[[0]]
  • Lamin Dm[[0]]
  • Lam[[Dm0]]
  • ldp1
  • LDP1
  • LFP
  • lfp
  • lgmd1b
  • LGMD1B
  • lmn1
  • LMN1
  • lmna-A
  • LMNC
  • lmnc
  • LMNL1
  • misg
  • nlam
  • PRO1
  • pro1
  • wu:fk66d12
Reactivity
Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
291
144
128
29
25
15
10
10
7
5
4
4
3
2
1
1
1
1
1
1
Host
Mouse
206
110
3
1
Clonality
Monoclonal
Conjugate
This Lamin A/C antibody is un-conjugated
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
272
107
98
77
61
57
33
31
30
23
11
2
2
2
2
2
1
1
Supplier
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Catalog No. ABIN112346
$ 390.50
Plus shipping costs $45.00

Top referenced anti-Lamin A/C antibody for Immunofluorescence

Similar anti-Lamin A/C Antibodies

Application / Reactivity Mouse (Murine) Rat (Rattus) Human Cow (Bovine) Dog (Canine) Hamster Sheep (Ovine)
Western Blotting (WB) 112 Antibodies 100 Antibodies 246 Antibodies 29 Antibodies 11 Antibodies 6 Antibodies 3 Antibodies
Indirect Immunofluorescence Assay (IFA) 1 Antibodies
Immunoprecipitation (IP) 33 Antibodies 7 Antibodies 5 Antibodies 2 Antibodies
Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 3 Antibodies 61 Antibodies 32 Antibodies 26 Antibodies
Immunohistochemistry (IHC) 13 Antibodies

General

Antigen Lamin A/C (LMNA) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
(291), (144), (128), (29), (25), (15), (10), (10), (7), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(206), (110), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Lamin A/C antibody is un-conjugated
(5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
(272), (107), (98), (77), (61), (57), (33), (31), (30), (23), (11), (2), (2), (2), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C Antibody (ABIN112346) Images
Specificity 131C3 reacts with an epitope located between residues 319-566 in Lamin A and C. Immunoblotting of 131C3 recognizes Nuclear Lamins A and C in Human Fibroblasts.
Purification Purified
Immunogen Purified Rat liver Lamins.
Clone 131C3
Isotype IgG1

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling References for anti-Lamin A/C Antibody (ABIN112346) Images back to top
Antigen
Alternative Name Lamin-A/C (LMNA) (LMNA Antibody Abstract)
Background Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.Synonyms: 70 kDa Lamin, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Gene ID 4000
NCBI Accession NP_005563
UniProt P02545
Research Area Cytoskeleton
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling References for anti-Lamin A/C Antibody (ABIN112346) Images back to top
Application Notes Immunoblotting: 1/100-1/1000. Flow Cytometry: 1/100-1/200. Immunocytochemistry. Immunohistochemistry on Frozen Sections: 1/100-1/200 with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details References for anti-Lamin A/C Antibody (ABIN112346) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Lamin A/C Antibody (ABIN112346)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Background publications

Neri, Raymond, Giordano, Capitani, Martelli: "Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells." in: Journal of cellular physiology, Vol. 178, Issue 3, pp. 284-95, 1999

Neri, Raymond, Giordano, Borgatti, Marchisio, Capitani, Martelli: "Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions." in: Journal of cellular biochemistry, Vol. 75, Issue 1, pp. 36-45, 1999

Pugh, Coates, Lane, Raymond, Quinlan: "Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells." in: Journal of cell science, Vol. 110 ( Pt 19), pp. 2483-93, 1997