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anti-Zebrafish (Danio rerio) Lamin A/C antibody for Immunohistochemistry (Frozen Sections)

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • 74/76
  • 2459
  • cb948
  • cdcd1
  • CDCD1
  • CDDC
  • cddc
  • CG6944
  • CMD1A
  • cmd1a
  • cmt2b1
  • CMT2B1
  • D5
  • Dhe
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • Dmel\\CG6944
  • DmLamin
  • DmO
  • Dmo
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • DM[[O]]
  • Dm[[o]]
  • emd2
  • EMD2
  • fk66d12
  • FPL
  • fpl
  • fpld
  • FPLD
  • FPLD2
  • HGPS
  • hgps
  • idc
  • IDC
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • LAM
  • lam
  • Lam(Dm0)
  • lamDm0
  • LamDm[[0]]
  • lamDm[[0]]
  • Lam Dm[[0]]
  • LamDm[[o]]
  • lamin
  • Lamin-A
  • lamin-L(III)-like
  • lamin Dm0
  • lamin Dm[[0]]
  • Lamin Dm[[0]]
  • Lam[[Dm0]]
  • ldp1
  • LDP1
  • LFP
  • lfp
  • lgmd1b
  • LGMD1B
  • lmn1
  • LMN1
  • lmna-A
  • LMNC
  • lmnc
  • LMNL1
  • misg
  • nlam
  • PRO1
  • pro1
  • wu:fk66d12
Reactivity
Cow (Bovine), Fish, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
378
206
189
87
45
39
24
22
17
10
4
4
4
3
1
1
1
1
1
Host
Mouse
213
188
5
1
Clonality
Monoclonal
Conjugate
This Lamin A/C antibody is un-conjugated
8
7
7
7
6
6
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
359
182
141
127
100
68
66
64
56
23
11
2
2
2
2
2
1
1
Supplier
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Catalog No. ABIN452378
$ 346.50
Plus shipping costs $45.00

Top referenced anti-Lamin A/C antibody for Immunohistochemistry (Frozen Sections)

Similar anti-Lamin A/C Antibodies

Application / Reactivity Mouse (Murine) Rat (Rattus) Human Cow (Bovine) Fish Xenopus laevis Zebrafish (Danio rerio)
Western Blotting (WB) 174 Antibodies 161 Antibodies 333 Antibodies 87 Antibodies 5 Antibodies 25 Antibodies 1 Antibodies
Indirect Immunofluorescence Assay (IFA) 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 56 Antibodies 8 Antibodies 6 Antibodies 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies 66 Antibodies 37 Antibodies 30 Antibodies

General

Antigen Lamin A/C (LMNA) Antibodies
Reactivity Cow (Bovine), Fish, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(378), (206), (189), (87), (45), (39), (24), (22), (17), (10), (4), (4), (4), (3), (1), (1), (1), (1), (1)
Host Mouse
(213), (188), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Lamin A/C antibody is un-conjugated
(8), (7), (7), (7), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
(359), (182), (141), (127), (100), (68), (66), (64), (56), (23), (11), (2), (2), (2), (2), (2), (1), (1)
Pubmed 6 references available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling References for anti-Lamin A/C Antibody (ABIN452378) Images
Specificity The monoclonal antibody decorates the lamina, i.e. the nucleoplasmic layer coating the nuclear envelope. Mutations in lamin A have been shown to cause Hutchinson-Gilford progeria syndrome in Human and Mouse and other laminopathies (for review see Burke & Stewart, 2002). Polypeptide(s) Reacting: Lamin isotypes A and C (Mr 60-75 kDa), meiotic lamin C2. Tested Reactivity on Cultured Cell Lines: RV-SMC (Rat Vascular Smooth Muscle Cells).
Cross-Reactivity (Details) Species reactivity (tested):Xenopus laevis (LA), Human (LA, C), Bovine (LA, C), Mouse (LA, C), Rat (LA, C), Trout (LA), Zebrafish (LA).
Characteristics Synonyms: LMNA, LMN1, 70 kDa Lamin, NY-REN-32, NYREN32, Lamin-A/C, Lamin A, Lamin A + C,Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Purification Supernatant
Immunogen Nuclear pore complex-lamina fraction of Bovine liver.
Clone R27
Isotype IgM

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling References for anti-Lamin A/C Antibody (ABIN452378) Images back to top
Antigen
Alternative Name Lamin-A/C (LMNA) (LMNA Antibody Abstract)
Background Lamin A and lamin C are alternative splicing products of the lamin A/C gene that is responsible for autosomal dominant Emery-Dreifuss muscular dystrophy (AD-EDMD). Aberrant expression patterns of nuclear lamins have been described in various types of cancer depending on the subtype of cancer, its aggressiveness, proliferative capacity and degree of differentiation. In general, the expression of A-type lamins (lamins A and C) has been correlated with a non-proliferating, differentiated state of cells and tissues. Lamins A and C, the products of the LMNA gene, are nuclear intermediate filament proteins and are the major structural components of the lamina network that underlies and supports the nuclear envelope.Synonyms: 70 kDa Lamin, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Gene ID 4000
UniProt P02545
Research Area Cytoskeleton
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling References for anti-Lamin A/C Antibody (ABIN452378) Images back to top
Application Notes Immunofluorescence Microscopy. Immunoblotting (Western). Working Dilution: Ready-to-use for Immunofluorescence microscopy. Incubation Time: 1 h at RT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details References for anti-Lamin A/C Antibody (ABIN452378) Images back to top
Format Liquid
Buffer 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-Lamin A/C Antibody (ABIN452378)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Background publications

Burke, Stewart: "Life at the edge: the nuclear envelope and human disease." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 8, pp. 575-85, 2002

von Glasenapp, Benavente: "Fate of meiotic lamin C2 in rat spermatocytes cultured in the presence of okadaic acid." in: Chromosoma, Vol. 109, Issue 1-2, pp. 117-22, 2000

Talbot, Geiske, Knoll: "Oocyte pickup by the mammalian oviduct." in: Molecular biology of the cell, Vol. 10, Issue 1, pp. 5-8, 1999

Höger, Grund, Franke, Krohne: "Immunolocalization of lamins in the thick nuclear lamina of human synovial cells." in: European journal of cell biology, Vol. 54, Issue 1, pp. 150-6, 1991

Franke: "Nuclear lamins and cytoplasmic intermediate filament proteins: a growing multigene family." in: Cell, Vol. 48, Issue 1, pp. 3-4, 1987

SAUER, CHITTENDEN: "Deoxyribonucleic acid content of cell nuclei in the neural tube of the chick embryo: evidence for intermitotic migration of nuclei." in: Experimental cell research, Vol. 16, Issue 1, pp. 1-6, 1959