anti-Zebrafish (Danio rerio) Lamin A/C antibody for Immunohistochemistry (Frozen Sections)

Recommended Lamin A/C Antibody (supplied by: Log in to see )

Antigen
Lamin A/C (LMNA) Antibodies
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • Dhe
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • lmna-A
  • lamin-L(III)-like
  • Lamin
  • lamin A
  • lamin A/C
  • lamin B3
  • Lam
  • lmna
  • LMNA
  • lmnb3
  • Lmna
Reactivity
Cow (Bovine), Fish, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
393
258
238
102
53
52
22
19
15
9
8
7
5
4
3
3
2
1
1
Host
Mouse
215
177
5
1
Clonality
Monoclonal
Conjugate
This Lamin A/C antibody is un-conjugated
10
8
8
6
6
6
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
350
164
127
123
99
78
64
58
47
27
11
9
2
2
1
1
Supplier
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Catalog No. ABIN452378
$ 357.50
Plus shipping costs $45.00

Top referenced anti-Lamin A/C antibody for Immunohistochemistry (Frozen Sections)

Similar anti-Lamin A/C Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine) Fish Xenopus laevis Zebrafish (Danio rerio)
Immunofluorescence (fixed cells) (IF/ICC) 9 Antibodies 7 Antibodies 7 Antibodies 2 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 219 Antibodies 202 Antibodies 346 Antibodies 97 Antibodies 5 Antibodies 10 Antibodies 1 Antibodies
Immunoprecipitation (IP) 47 Antibodies 20 Antibodies

General

Antigen Lamin A/C (LMNA) Antibodies
Reactivity Cow (Bovine), Fish, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(393), (258), (238), (102), (53), (52), (22), (19), (15), (9), (8), (7), (5), (4), (3), (3), (2), (1), (1)
Host Mouse
(215), (177), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Lamin A/C antibody is un-conjugated
(10), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
(350), (164), (127), (123), (99), (78), (64), (58), (47), (27), (11), (9), (2), (2), (1), (1)
Pubmed 6 references available
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Product Details anti-Lamin A/C Antibody

Target Details Lamin A/C Application Details Handling ProductDetails: References for anti-Lamin A/C antibody (ABIN452378) Images
Specificity The monoclonal antibody decorates the lamina, i.e. the nucleoplasmic layer coating the nuclear envelope. Mutations in lamin A have been shown to cause Hutchinson-Gilford progeria syndrome in Human and Mouse and other laminopathies (for review see Burke & Stewart, 2002). Polypeptide(s) Reacting: Lamin isotypes A and C (Mr 60-75 kDa), meiotic lamin C2. Tested Reactivity on Cultured Cell Lines: RV-SMC (Rat Vascular Smooth Muscle Cells).
Cross-Reactivity (Details) Species reactivity (tested):Xenopus laevis (LA), Human (LA, C), Bovine (LA, C), Mouse (LA, C), Rat (LA, C), Trout (LA), Zebrafish (LA).
Characteristics Synonyms: LMNA, LMN1, 70 kDa Lamin, NY-REN-32, NYREN32, Lamin-A/C, Lamin A, Lamin A + C,Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Purification Supernatant
Immunogen Nuclear pore complex-lamina fraction of Bovine liver.
Clone R27
Isotype IgM

Target Details Lamin A/C

Product Details anti-Lamin A/C Antibody Application Details Handling ProductDetails: References for anti-Lamin A/C antibody (ABIN452378) Images back to top
Antigen
Alternative Name Lamin-A/C (LMNA) (LMNA Antibody Abstract)
Background Lamin A and lamin C are alternative splicing products of the lamin A/C gene that is responsible for autosomal dominant Emery-Dreifuss muscular dystrophy (AD-EDMD). Aberrant expression patterns of nuclear lamins have been described in various types of cancer depending on the subtype of cancer, its aggressiveness, proliferative capacity and degree of differentiation. In general, the expression of A-type lamins (lamins A and C) has been correlated with a non-proliferating, differentiated state of cells and tissues. Lamins A and C, the products of the LMNA gene, are nuclear intermediate filament proteins and are the major structural components of the lamina network that underlies and supports the nuclear envelope.Synonyms: 70 kDa Lamin, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Gene ID 4000
UniProt P02545
Research Area Cytoskeleton
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Handling ProductDetails: References for anti-Lamin A/C antibody (ABIN452378) Images back to top
Application Notes Immunofluorescence Microscopy. Immunoblotting (Western). Working Dilution: Ready-to-use for Immunofluorescence microscopy. Incubation Time: 1 h at RT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details ProductDetails: References for anti-Lamin A/C antibody (ABIN452378) Images back to top
Format Liquid
Buffer 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.
Expiry Date 12 months

ProductDetails: References for anti-Lamin A/C antibody (ABIN452378)

Product Details anti-Lamin A/C Antibody Target Details Lamin A/C Application Details Handling Images back to top
Background publications

Burke, Stewart: "Life at the edge: the nuclear envelope and human disease." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 8, pp. 575-85, 2002

von Glasenapp, Benavente: "Fate of meiotic lamin C2 in rat spermatocytes cultured in the presence of okadaic acid." in: Chromosoma, Vol. 109, Issue 1-2, pp. 117-22, 2000

Talbot, Geiske, Knoll: "Oocyte pickup by the mammalian oviduct." in: Molecular biology of the cell, Vol. 10, Issue 1, pp. 5-8, 1999

Höger, Grund, Franke, Krohne: "Immunolocalization of lamins in the thick nuclear lamina of human synovial cells." in: European journal of cell biology, Vol. 54, Issue 1, pp. 150-6, 1991

Franke: "Nuclear lamins and cytoplasmic intermediate filament proteins: a growing multigene family." in: Cell, Vol. 48, Issue 1, pp. 3-4, 1987

SAUER, CHITTENDEN: "Deoxyribonucleic acid content of cell nuclei in the neural tube of the chick embryo: evidence for intermitotic migration of nuclei." in: Experimental cell research, Vol. 16, Issue 1, pp. 1-6, 1959