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Browse our Lamin A/C Proteins (LMNA)

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Lamin A/C Proteins (LMNA)
On are 10 Lamin A/C (LMNA) Proteins from 5 different suppliers available. Additionally we are shipping Lamin A/C Antibodies (322) and Lamin A/C Kits (25) and many more products for this protein. A total of 375 Lamin A/C products are currently listed.
74/76, 2459, cb948, CDCD1, CDDC, CG6944, CMD1A, CMT2B1, D5, Dhe, Dm, Dm(0), Dm0, Dm1, Dm2, Dmel\\CG6944, DmLamin, Dmo, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], Dm[[o]], EMD2, fk66d12, FPL, FPLD, FPLD2, HGPS, IDC, jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, lam, Lam(Dm0), lamDm0, lamDm[[0]], Lam Dm[[0]], LamDm[[o]], lamin, Lamin-A, lamin-L(III)-like, lamin Dm0, lamin Dm[[0]], Lam[[Dm0]], LDP1, LFP, LGMD1B, LMN1, lmna-A, LMNC, LMNL1, misg, nlam, PRO1, wu:fk66d12
list all proteins Gene Name GeneID UniProt
LMNA 16905 P48678
LMNA 4000 P02545
LMNA 60374 P48679

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Lamin A/C Proteins (LMNA) by Origin

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Top referenced Lamin A/C Proteins

  1. Human Lamin A/C Protein expressed in Wheat germ - ABIN1309507 : Chen, Lin, Chow, Lee: Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells. in Proteomics 2011 (PubMed)
    Show all 2 references for ABIN1309507

More Proteins for Lamin A/C Interaction Partners

Fruit Fly (Drosophila melanogaster) Lamin A/C (LMNA) interaction partners

  1. The loss of lamin-B (show LMNB1 Proteins) leads to systemic inflammation and aging.

  2. nuclear Wash interacts with B-type Lamin (Lamin Dm0), and, like Lamin, Wash associates with constitutive heterochromatin

  3. of single phosphorylation sites of Drosophila melanogaster lamin Dm and lamin C

  4. Rab5 associated in vivo with nuclear Lamin and mushroom body defect (Mud), the Drosophila counterpart of nuclear mitotic apparatus protein (NuMA).

  5. Kugelkern and lamin Dm0 affect nuclear shape without requiring filament formation or the presence of a classical nuclear lamina.

  6. Lamin mutation is associated with neuromuscular defects and premature aging.

  7. prometaphase spindle can be made robust to natural fluctuations in motor ratios by a disassembling lamin-B (show LMNB1 Proteins) envelope.

  8. Molecular interactions with lamin Dm0 may link JIL-1 kinase to nuclear morphology and integrity of nurse cells during oogenesis.

  9. The lamin Dm0 allele Ari3 acts as an enhancer of position effect variegation of the wm4 allele in Drosophila.

  10. Both lamin Dm0 and C. elegans Ce-lamin bind directly to histone H2A in vitro and this binding requires the nuclear localization signal

Zebrafish Lamin A/C (LMNA) interaction partners

  1. results have important implications for understanding the tissue-specific regulation and functions of the lamin A gene

  2. The induction of embryonic senescence and laminopathies in zebrafish harboring disturbed expressions of the lamin A gene, is described.

Mouse (Murine) Lamin A/C (LMNA) interaction partners

  1. administration of the exon 11 ASO reduced lamin A expression in wild-type mice and progerin expression in an HGPS mouse model.

  2. stabilization of perinuclear actin strengthens the transient interactions of lamin A with chromatin

  3. It was found that the lamin A protein expressed in mouse ear cartilage cells is shorter than protein expressed in mouse skin. This difference in protein length could be caused by differential cleavage in the cells of skin and ear cartilage tissues

  4. Annexin, lamin, and vimentin (show VIM Proteins) were identified as universal dystrophic markers

  5. These results identify SNX6 (show SNX6 Proteins) as a key regulator of lamin A synthesis and incorporation into the nuclear envelope.

  6. loss of Lmna under malignant conditions may, to a limited extent, enhance polyp size indicating that A-type lamins may regulate cell proliferation in the transformed GI epithelium

  7. The results presented in this work indicate that the detrimental effects of lamin A expression were less than anticipated in the brain, even after 90 weeks of transgenic expression.

  8. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

  9. Results suggest that lamin A/C is critical for proper structural and functional development of the sperm acrosome and head shape.

  10. progerin and p16(INK4a) expression, beta-galactosidase (show GLB1 Proteins) activity, and reactive oxygen species, which increase with age, were higher in young Xpc (show XPC Proteins)(-/-) mice than in young Xpc (show XPC Proteins)(+/+) ones

Human Lamin A/C (LMNA) interaction partners

  1. the C to T mutation at the rs4641 locus of LMNA could enhance the risk of DCM, and that rs4641 represented a genetic susceptibility locus.

  2. Lamin A promotes SIRT6 (show SIRT6 Proteins)-dependent DNA-PKcs (DNA-PK catalytic subunit (show PRKDC Proteins)) recruitment to chromatin.

  3. Development of tumor initiating cells in neuroblastoma (show ARHGEF16 Proteins) is due to an increased expression of MYCN (show MYCN Proteins) gene. In neuroblastoma (show ARHGEF16 Proteins) an inverse relationship exists between LMNA and MYCN (show MYCN Proteins) expression.

  4. The cardiomyocytes carrying the LMNA D192G mutation have an increased nuclear Young modulus compared to control NRVMs as well as NRVMs expressing wild-type LMNA.

  5. Data show that lamins A and B are differently processed in staurosporine and beta-Amyloid peptide (show APP Proteins) fragments Abeta42-treated cells.

  6. interactions between SIM3 of lamin A and a putative SUMO2 (show SUMO2 Proteins)-modified protein plays an important role in the reorganization of the nuclear lamina at the end of mitosis.

  7. The study identified three patients with Emery-Dreifuss muscular dystrophy exhibiting the same dominant LMNA mutation and presenting with a spectrum of severe cardiac abnormalities.

  8. The findings unveil a unique mechanism where the nuclear periphery proteins lamin-A/C, LAP2alpha and BAF1 are assembled into a protein complex during mitosis in order to regulate assembly and positioning of the mitotic spindle.

  9. The authors find that LAP2alpha (lamina-associated polypeptide-alpha) interacts with lamin A, while its interaction with progerin is significantly reduced.

  10. our studies demonstrate that lamin A/C plays a significant role in the differentiation of both osteoblasts and adipocytes by regulating some of the elements of Wnt/b-catenin signaling during early MSC (show MSC Proteins) differentiation

Pig (Porcine) Lamin A/C (LMNA) interaction partners

  1. Both anti-lamin A/C and anti-lamin B (show LMNB1 Proteins) staining were clearly present in all embryonic stages.

  2. A study mapping the location of procine lamin type A to chromosome 4q is presented.

Xenopus laevis Lamin A/C (LMNA) interaction partners

  1. These results indicate that thyroid hormone (show PTH Proteins)-regulated expression of nuclear lamin A and LIII closely correlates with dedifferentiation of the epithelial cells in the X. laevis intestine.

  2. LIII filaments appear identical to the endogenous lamina, whereas lamin B2 (show LMNB2 Proteins) assembles into filaments that are organized less precisely; Lamin A induces sheets of thicker filaments on the endogenous lamina and increases the rigidity of the nuclear envelope

Lamin A/C (LMNA) Protein Profile

Protein Summary

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Alternative names and synonyms associated with Lamin A/C (LMNA)

  • Lamin (Lam)
  • lamin A (lmna)
  • lamin A/C (LMNA)
  • lamin B3 (lmnb3)
  • lamin A/C (lmna)
  • lamin A (Lmna)
  • lamin A/C (Lmna)
  • 74/76 protein
  • 2459 protein
  • cb948 protein
  • CDCD1 protein
  • CDDC protein
  • CG6944 protein
  • CMD1A protein
  • CMT2B1 protein
  • D5 protein
  • Dhe protein
  • Dm protein
  • Dm(0) protein
  • Dm0 protein
  • Dm1 protein
  • Dm2 protein
  • Dmel\\CG6944 protein
  • DmLamin protein
  • Dmo protein
  • Dm[[0]] protein
  • Dm[[1]] protein
  • Dm[[2]] protein
  • Dm[[mit]] protein
  • Dm[[o]] protein
  • EMD2 protein
  • fk66d12 protein
  • FPL protein
  • FPLD protein
  • FPLD2 protein
  • HGPS protein
  • IDC protein
  • jf27 protein
  • l(2)04643 protein
  • l(2)25Ec protein
  • l(2)gdh-7 protein
  • l(2)gdh7 protein
  • l(2)jf27 protein
  • lam protein
  • Lam(Dm0) protein
  • lamDm0 protein
  • lamDm[[0]] protein
  • Lam Dm[[0]] protein
  • LamDm[[o]] protein
  • lamin protein
  • Lamin-A protein
  • lamin-L(III)-like protein
  • lamin Dm0 protein
  • lamin Dm[[0]] protein
  • Lam[[Dm0]] protein
  • LDP1 protein
  • LFP protein
  • LGMD1B protein
  • LMN1 protein
  • lmna-A protein
  • LMNC protein
  • LMNL1 protein
  • misg protein
  • nlam protein
  • PRO1 protein
  • wu:fk66d12 protein

Protein level used designations for Lamin A/C Proteins (LMNA)

B-type lamin , CG6944-PA , CG6944-PB , CG6944-PC , Lam-PA , Lam-PB , Lam-PC , Lamin-B , LaminDm , LaminDm0 , alpha-Lamin , intermediate filament-like lamina , lamin , lamin A , lamin B , lamin D , lamin D[[0]] , lamin D[[m]]0 , lamin D[[o]] , lamin Dm0 , lamin Dm[[0]] , lamin Dmo , lethal(2)25Ec , misguided , misrouted , n-lamin , nuclear lamin , prelamin-A/C , lamin B3 , lamin A/C , lamin LIII , lamin-A/C-like , lamin C , lamin-A/C , 70 kDa lamin , lamin A/C-like 1 , renal carcinoma antigen NY-REN-32 , lamin C2 , lamin-A

33782 Drosophila melanogaster
195815 Danio rerio
457385 Pan troglodytes
719414 Macaca mulatta
733537 Xenopus (Silurana) tropicalis
733973 Xenopus (Silurana) tropicalis
100401580 Callithrix jacchus
100603145 Nomascus leucogenys
16905 Mus musculus
4000 Homo sapiens
60374 Rattus norvegicus
480124 Canis lupus familiaris
404144 Bos taurus
101107924 Ovis aries
100126859 Sus scrofa
373673 Xenopus laevis
415464 Gallus gallus
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