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anti-Human NAIP antibody for Immunofluorescence

Recommended NAIP Antibody (supplied by: Log in to see )

Antigen
NLR Family, Apoptosis Inhibitory Protein (NAIP) Antibodies
  • BIRC1
  • Birc1
  • Birc1a
  • Birc1b
  • Naip
  • Naip2
  • NLRB1
  • psiNAIP
Epitope
C-Term
12
10
2
1
1
Reactivity
Human
48
4
1
Host
Rabbit
37
13
1
Clonality
Polyclonal
Conjugate
This NAIP antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
25
23
11
11
9
5
3
3
2
1
Supplier
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Catalog No. ABIN500306
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010843406 ABIN303180 IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0010843406 ABIN2315159 IC IF ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
0.0010843406 ABIN4337756 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Top referenced anti-NAIP antibody for Immunofluorescence

Similar anti-NAIP Antibodies

Application / Reactivity Human
ELISA 23 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Western Blotting (WB) 23 Antibodies

General

Antigen NLR Family, Apoptosis Inhibitory Protein (NAIP) Antibodies
Epitope C-Term
(12), (10), (2), (1), (1)
Reactivity Human
(48), (4), (1)
Host Rabbit
(37), (13), (1)
Clonality
Polyclonal
Conjugate This NAIP antibody is un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(25), (23), (11), (11), (9), (5), (3), (3), (2), (1)
Pubmed 2 references available
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Product Details anti-NAIP Antibody

Target Details NAIP Application Details Handling References for anti-NAIP Antibody (ABIN500306) Images
Specificity This antibody detects NAIP at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Peptide affinity chromatography
Immunogen NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.
Isotype IgG

Target Details NAIP

Product Details anti-NAIP Antibody Application Details Handling References for anti-NAIP Antibody (ABIN500306) Images back to top
Antigen
Alternative Name NAIP (NAIP Antibody Abstract)
Background Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy (1,2). Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR), these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO (4), suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported (5).Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1
Gene ID 4671
UniProt Q13075
Pathways Apoptosis

Application Details

Product Details anti-NAIP Antibody Target Details NAIP Handling References for anti-NAIP Antibody (ABIN500306) Images back to top
Application Notes ELISA. Western blot: 0.5 to 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NAIP Antibody Target Details NAIP Application Details References for anti-NAIP Antibody (ABIN500306) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-NAIP Antibody (ABIN500306)

Product Details anti-NAIP Antibody Target Details NAIP Application Details Handling Images back to top
Background publications

Davoodi, Lin, Kelly, Liston, MacKenzie: "Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40622-8, 2004

Liston, Fong, Korneluk: "The inhibitors of apoptosis: there is more to life than Bcl2." in: Oncogene, Vol. 22, Issue 53, pp. 8568-80, 2003

Images

Product Details anti-NAIP Antibody Target Details NAIP Application Details Handling References for anti-NAIP Antibody (ABIN500306) back to top
Supplier Images
Immunofluorescence (IF) image for anti-NAIP antibody (NLR Family, Apoptosis Inhibitory Protein) (C-Term) (ABIN500306) Immunocytochemistry of NAIP in A549 cells with NAIP antibody at 10 μg/ml.
Western Blotting (WB) image for anti-NAIP antibody (NLR Family, Apoptosis Inhibitory Protein) (C-Term) (ABIN500306) Western blot analysis of NAIP in PC-3 cell lysate with this product at (A) 0.5, (B) 1...