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Browse our PARP1 (PARP1) ELISA Kits

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Poly (ADP-Ribose) Polymerase 1 ELISA Kits (PARP1)
On are 32 Poly (ADP-Ribose) Polymerase 1 (PARP1) ELISA Kits from 6 different suppliers available. Additionally we are shipping PARP1 Antibodies (426) and PARP1 Proteins (25) and many more products for this protein. A total of 511 PARP1 products are currently listed.
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1
list all ELISA KIts Gene Name GeneID UniProt
PARP1 142 P09874
PARP1 25591 P27008
PARP1 11545  

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More ELISA Kits for PARP1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (show H2AFV ELISA Kits) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  2. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  3. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  4. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  5. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  6. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  7. PARP-e autoregulates Parp transcription

  8. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

  9. PARP1 is required for protein targeting to Cajal body.

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1/2 and tankyrase 1 (show TNKS ELISA Kits)/2 inhibitor which has the advantage of targeting Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling addicted tumors.

  2. Non-small cell lung cancer patients with high intra-tumoral PARP1 activity had a poor prognosis.

  3. DNA damage induced necrosis through a PARP1-dependent and p53 (show TP53 ELISA Kits)-independent pathway.

  4. Data indicate that poly(ADP-ribose) polymerase 1 (PARP1) protein is expressed in pediatric high-grade astrocytomas (pHGA) and diffuse intrinsic pontine gliomas (DIPG) patient samples and cell lines.

  5. The initial affinity between the PARP1, PARP2 (show PARP2 ELISA Kits) and the DNA damaged site appears to influence both the size of the Poly(ADP-Ribose) synthesized and the time of residence of PARylated PARP1 and PARP2 (show PARP2 ELISA Kits) on DNA damages.

  6. Our combination strategy could expand the clinical application of PARP (show COL11A2 ELISA Kits)-inhibitors to non-BRCA mutated cancers and may target a new group of NSCLC patients who show limited response to current therapies.

  7. PARP-1 has an important role in the progression of acute myeloid leukemia (show BCL11A ELISA Kits) by suppressing the myeloproliferative leukemia virus oncogene (show MPL ELISA Kits)

  8. Data suggest that inhibition of PARP1 (preferential inhibition of PARP1 over PARP2 (show PARP2 ELISA Kits)) arrests cell cycle/cell proliferation and promotes apoptosis of breast tumor cells (including triple negative breast tumor cells).

  9. Activation of the PI3K (show PIK3CA ELISA Kits)/mTOR (show FRAP1 ELISA Kits) Pathway following PARP (show COL11A2 ELISA Kits) Inhibition in Small Cell Lung Cancer.

  10. Noncovalent binding of ADP-ribose polymers with TET1 catalytic domain decreases TET1 hydroxylase activity while the covalent PARylation stimulates TET1 enzyme. In addition, TET1 activates PARP-1/ARTD1 independently of DNA breaks.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. ADPRT Val762Ala and APE1 (show APEX1 ELISA Kits) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  2. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  3. FGF2 (show FGF2 ELISA Kits) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (show MAPK1 ELISA Kits))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. Data show reduced tumor burden through increased oxidative stress in lung adenocarcinoma cells of PARP-1 and PARP-2 (show PARP2 ELISA Kits) knockout mice.

  2. By enhancing PARP1 activity, ULK1 (show ULK1 ELISA Kits) contributes to ATP depletion and death of H2O2-treated cells.

  3. PARP-1 deficiency significantly increased the chromatin binding affinity of MeCP2 (show MECP2 ELISA Kits) in vivo.

  4. these results identify CHD1L (show CHD1L ELISA Kits) as a key chromatin remodeler involved in PARP1/PARylation-regulated early-stage reprogramming and pluripotency in stem cells.

  5. PARP-1 activation is required for the consolidation, reconsolidation, and extinction of contextual fear memory

  6. Suggest role for LRP1 (show LRP1 ELISA Kits)/PARP1 signaling in endothelial cell proliferation and retinal neovascularization induced by hypoxia.

  7. Matrix Metalloproteinase-2 (MMP-2 (show MMP2 ELISA Kits)) Gene Deletion Enhances MMP-9 (show MMP9 ELISA Kits) Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice

  8. PARP-1 inhibition blocks glioma conditioned medium-induced endothelial migration by interfering with ERK (show EPHB2 ELISA Kits) signal-transduction pathway.

  9. The results demonstrate that ARTD1 modulates IL-6 expression by regulating the function of an NF-kappaB enhanceosome complex, which involves MLL1 and does not require ADP-ribosylation.

  10. Results show the stimulatory effect of PARP-1 on APE1 (show APEX1 ELISA Kits)-dependent base excision repair (BER). PARP-1 and APE1 (show APEX1 ELISA Kits) appear to have a functional interaction in BER since PARP-1 can stimulate the strand incision activity of APE1 (show APEX1 ELISA Kits).

PARP1 Antigen Profile

Antigen Summary

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (PARP1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (Parp1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (parp1) Elisa Kit
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) Elisa Kit
  • poly ADP-ribose polymerase (Parp) Elisa Kit
  • 5830444G22Rik Elisa Kit
  • Adprp Elisa Kit
  • Adprt Elisa Kit
  • ADPRT 1 Elisa Kit
  • Adprt1 Elisa Kit
  • AI893648 Elisa Kit
  • ARTD1 Elisa Kit
  • BEST:LD21673 Elisa Kit
  • C80510 Elisa Kit
  • CG17685 Elisa Kit
  • CG17696 Elisa Kit
  • CG17718 Elisa Kit
  • CG40411 Elisa Kit
  • D.PARP Elisa Kit
  • Dm.pARTa Elisa Kit
  • Dmel\\CG40411 Elisa Kit
  • dPARP Elisa Kit
  • LD21673.3prime Elisa Kit
  • padprt-1 Elisa Kit
  • parp Elisa Kit
  • parp-1 Elisa Kit
  • PARP1 Elisa Kit
  • ppol Elisa Kit
  • sPARP-1 Elisa Kit

Protein level used designations for PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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