anti-Human TNFRSF10A antibody for Enzyme Immunoassay

Recommended TNFRSF10A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) Antibodies
  • APO2
  • CD261
  • DR4
  • TRAILR-1
  • TRAILR1
  • TNFRSF10A
  • tumor necrosis factor receptor superfamily, member 10a
  • TNFRSF10A
Reactivity
Human
302
27
24
1
Host
Rabbit
227
73
1
Clonality
Polyclonal
Conjugate
This TNFRSF10A antibody is un-conjugated
22
18
10
10
8
7
7
7
7
7
6
5
5
5
5
5
5
5
4
4
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
186
126
74
48
45
35
28
14
10
9
7
6
5
3
2
2
2
2
2
1
1
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Catalog No. ABIN272303
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554760 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN5554761 EIA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2717645 EIA Rabbit IgG Log in to see Polyclonal

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) Antibodies
Reactivity Human
(302), (27), (24), (1)
Host Rabbit
(227), (73), (1)
Clonality
Polyclonal
Conjugate This TNFRSF10A antibody is un-conjugated
(22), (18), (10), (10), (8), (7), (7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(186), (126), (74), (48), (45), (35), (28), (14), (10), (9), (7), (6), (5), (3), (2), (2), (2), (2), (2), (1), (1)
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Product Details anti-TNFRSF10A Antibody

Target Details TNFRSF10A Application Details Handling Images
Specificity This antibody detects endogenous levels of DR4 protein. (region surrounding Asp430)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target Details TNFRSF10A

Product Details anti-TNFRSF10A Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD261 / TRAILR1 (TNFRSF10A Antibody Abstract)
Background Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which, includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the death domain, that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (Death Receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
Molecular Weight approx. 50 kDa
Gene ID 8797
NCBI Accession NP_003835
UniProt O00220
Research Area Signaling, Apoptosis/Necrosis
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Handling Images back to top
Application Notes ELISA: 1: 000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Application Details Handling back to top
Supplier Images
 image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (ABIN272303) anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody