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anti-Human TNFRSF10A antibody for Enzyme Immunoassay

Recommended TNFRSF10A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) Antibodies
  • APO2
  • CD261
  • DR4
  • TNFRSF10A
  • TRAILR-1
  • TRAILR1
Epitope
C-Term
28
15
12
9
5
5
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Human
170
2
2
1
Host
Rabbit
102
66
1
Clonality
Polyclonal
Conjugate
This TNFRSF10A antibody is un-conjugated
14
12
8
7
4
4
2
2
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
85
84
40
38
32
25
8
7
7
6
6
3
2
2
Supplier
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Catalog No. ABIN499762
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000888695 ABIN499764 EIA WB Rabbit IgG N-Term Log in to see Polyclonal 4
0.000888695 ABIN272303 EIA WB Rabbit Log in to see Polyclonal
0.000888695 ABIN2717645 EIA Rabbit IgG Log in to see Polyclonal

Top referenced anti-TNFRSF10A antibody for Enzyme Immunoassay

Similar anti-TNFRSF10A Antibodies

Application / Reactivity Human
ELISA 33 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 87 Antibodies
Functional Studies (Func) 25 Antibodies
Immunochromatography (IC) 6 Antibodies
Immunocytochemistry (ICC) 38 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 40 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 6 Antibodies
Western Blotting (WB) 86 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) Antibodies
Epitope C-Term
(28), (15), (12), (9), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(170), (2), (2), (1)
Host Rabbit
(102), (66), (1)
Clonality
Polyclonal
Conjugate This TNFRSF10A antibody is un-conjugated
(14), (12), (8), (7), (4), (4), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(85), (84), (40), (38), (32), (25), (8), (7), (7), (6), (6), (3), (2), (2)
Pubmed 4 references available
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Product Details anti-TNFRSF10A Antibody

Target Details TNFRSF10A Application Details Handling References for anti-TNFRSF10A Antibody (ABIN499762) Images
Specificity DR4 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DR4 protein.
Purification DEAE
Immunogen Human DR4 (C-Terminus) Peptide
Isotype IgG

Target Details TNFRSF10A

Product Details anti-TNFRSF10A Antibody Application Details Handling References for anti-TNFRSF10A Antibody (ABIN499762) Images back to top
Antigen
Alternative Name CD261 / TRAILR1 (TNFRSF10A Antibody Abstract)
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL2,3, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kappaB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
Gene ID 8797
UniProt O00220
Research Area Signaling, Apoptosis/Necrosis
Pathways Apoptosis

Application Details

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Handling References for anti-TNFRSF10A Antibody (ABIN499762) Images back to top
Application Notes ELISA. Western Blot: 1/500 to 1/1000. A 57 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Application Details References for anti-TNFRSF10A Antibody (ABIN499762) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-TNFRSF10A Antibody (ABIN499762)

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Application Details Handling Images back to top
Background publications

Schneider, Thome, Burns, Bodmer, Hofmann, Kataoka, Holler, Tschopp: "TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB." in: Immunity, Vol. 7, Issue 6, pp. 831-6, 1998

Pan, ORourke, Chinnaiyan, Gentz, Ebner, Ni, Dixit: "The receptor for the cytotoxic ligand TRAIL." in: Science (New York, N.Y.), Vol. 276, Issue 5309, pp. 111-3, 1997

Wiley, Schooley, Smolak, Din, Huang, Nicholl, Sutherland, Smith, Rauch, Smith: "Identification and characterization of a new member of the TNF family that induces apoptosis." in: Immunity, Vol. 3, Issue 6, pp. 673-82, 1996

Pitti, Marsters, Ruppert, Donahue, Moore, Ashkenazi: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, 1996

Images

Product Details anti-TNFRSF10A Antibody Target Details TNFRSF10A Application Details Handling References for anti-TNFRSF10A Antibody (ABIN499762) back to top
Supplier Images
Immunofluorescence (IF) image for anti-TNFRSF10A antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10a) (C-Term) (ABIN499762) Immunocytochemistry of DR4 in Jurkat cells with AP30299PU-N DR4 antibody at 10 μg/ml.
Western Blotting (WB) image for anti-TNFRSF10A antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10a) (C-Term) (ABIN499762) Western blot analysis of DR4 in HeLa total cell lysate with AP30299PU-N DR4 antibody ...