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|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) Antibodies|
|Conjugate||This TNFRSF10C antibody is conjugated to FITC Alternatives|
Flow Cytometry (FACS), Immunoprecipitation (IP)
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Product Details anti-TNFRSF10C AntibodyTarget Details TNFRSF10C Application Details Handling Images
|Specificity||This antibody recognises CD263, a 60 kDa cell surface protein.|
|Characteristics||Synonyms: Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3, Tumor necrosisfactor receptor superfamily member 10C, Decoy TRAIL receptor without death domain,TNF-related apoptosis-inducing ligand receptor 3, Trail receptor without an intracellulardomain, Lymphocyte inhibitor of TRAIL, Antagonist decoy receptor for TRAIL/Apo-2L|
|Purification||Affinity chromatography on Protein G|
|Immunogen||DcR1-Fc chimaeric protein. Lymph node cells from immunised mice were fused with cells ofthe P3U1 myeloma cell line.|
Target Details TNFRSF10CProduct Details anti-TNFRSF10C Antibody Application Details Handling Images back to top
|Alternative Name||CD263 / TRAILR3 (TNFRSF10C Antibody Abstract)|
|Background||CD263 is a member of the tumour necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumour cells.Synonyms: Antagonist decoy receptor for TRAIL/Apo-2L, DCR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRID, Trail receptor without an intracellular domain, Tumor necrosis factor receptor superfamily member 10C|
|Research Area||Signaling, Apoptosis/Necrosis|
Application DetailsProduct Details anti-TNFRSF10C Antibody Target Details TNFRSF10C Handling Images back to top
Flow cytometry (Neat - 1/10): use 10 μL of the suggested working dilution to label 1x10^6cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF10C Antibody Target Details TNFRSF10C Application Details Images back to top
|Buffer||PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
|Expiry Date||12 months|