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Browse our TNFRSF10C Proteins (TNFRSF10C)

Full name:
Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain Proteins (TNFRSF10C)
On www.antibodies-online.com are 7 Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) Proteins from 4 different suppliers available. Additionally we are shipping TNFRSF10C Antibodies (112) and TNFRSF10C Kits (8) and many more products for this protein. A total of 130 TNFRSF10C products are currently listed.
Synonyms:
CD263, DCR1, DCR1-TNFR, LIT, TNFRSF10C, TRAIL-R3, TRAILR3, TRID
list all proteins Gene Name GeneID UniProt
TNFRSF10C 8794 O14798

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TNFRSF10C Proteins (TNFRSF10C) by Origin

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Human Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) interaction partners

  1. Results identified epigenetic inactivation of TNFRSF10C and TNFRSF10D (show TNFRSF10D Proteins) in majority of cervical cancer cases.

  2. DcR1 levels in serum sample which were significantly lower in AMD (show AMD1 Proteins) patients.

  3. DcR1 upregulation mediates temozolomide resistance.

  4. The membrane expression of the TRAIL receptors DR4 (show HLADRB4 Proteins), DR5 (show TNFRSF10B Proteins), DcR1 and DcR2 (show CCR6 Proteins) is greater in normal endometrium than endometrioid adenocarcinoma (EAC (show CYLD Proteins)). The level of the receptors in EAC (show CYLD Proteins) is not dependent on grading and staging and does not predict survival.

  5. the results presented here claim for a relevant impact of aberrant methylation of decoy receptors in melanoma and allow to understand how the silencing of DcR1 and DcR2 (show CCR6 Proteins) is related to melanomagenesis.

  6. GATA4 (show GATA4 Proteins) and DcR1 promoter hypermethylation is tumor specific event in glioblastoma but they promoter methylation cannot be considered as a prognostic marker of glioblastoma survival.

  7. Primary EOC is associated to a lower TRAIL-R3 expression.

  8. Data show that about 20% of AML (show RUNX1 Proteins) patients highly expressed decoy receptor TRAIL-R3, which was strongly correlated to a shortened overall survival.

  9. Decoy receptors DcR1 and DcR2 (show CCR6 Proteins) on CD8 (show CD8A Proteins)+ T cells, but not on CD4 (show CD4 Proteins)-positive T cells, are positively correlated with patients' DAS (show ube3a Proteins) scores.

  10. Results suggest that DcR1 expression occurs in a subset of endometrial carcinomas and may contribute to resistance to TRAIL-induced apoptosis.

TNFRSF10C Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Alternative names and synonyms associated with TNFRSF10C

  • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C)
  • CD263 protein
  • DCR1 protein
  • DCR1-TNFR protein
  • LIT protein
  • TNFRSF10C protein
  • TRAIL-R3 protein
  • TRAILR3 protein
  • TRID protein

Protein level used designations for TNFRSF10C

TNF-related apoptosis-inducing ligand receptor 3 , antagonist decoy receptor for TRAIL/Apo-2L , cytotoxic TRAIL receptor-3 , decoy TRAIL receptor without death domain , decoy receptor 1 , lymphocyte inhibitor of TRAIL , tumor necrosis factor receptor superfamily member 10C , tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

GENE ID SPECIES
8794 Homo sapiens
472713 Pan troglodytes
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