Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human TNFRSF12A Antibodies:
anti-Mouse (Murine) TNFRSF12A Antibodies:
anti-Rat (Rattus) TNFRSF12A Antibodies:
Go to our pre-filtered search.
Human Monoclonal TNFRSF12A Primary Antibody for FACS, CyTOF - ABIN2661016
Lynch, Wang, Lund, Chen, Leal, Wiley: TWEAK induces angiogenesis and proliferation of endothelial cells. in The Journal of biological chemistry 1999
Show all 7 references for ABIN2661016
Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663248
Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. in Journal of immunology (Baltimore, Md. : 1950) 2002
Show all 7 references for ABIN2663248
Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663247
Feng, Guo, Factor, Thorgeirsson, Bell, Testa, Peifley, Winkles: The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. in The American journal of pathology 2000
Show all 6 references for ABIN2663247
Human Polyclonal TNFRSF12A Primary Antibody for EIA, IHC (p) - ABIN499851
Brown, Richards, Hanscom, Feng, Winkles: The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. in The Biochemical journal 2003
Show all 4 references for ABIN499851
Human Polyclonal TNFRSF12A Primary Antibody for WB - ABIN252585
Chorianopoulos, Heger, Lutz, Frank, Bea, Katus, Frey: FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK. in Basic research in cardiology 2010
In this review article, we summarize studies indicating that (i) Fn14 gene expression is low in normal brain tissue but is upregulated in advanced brain cancers and, in particular, in GB tumors ; TWEAK (show TNFSF12 Antibodies): Fn14 engagement as well as Fn14 overexpression can stimulate glioma cell migration, invasion and resistance to chemotherapeutic agents in vitro.
Fn14 is a receptor of mitogen TWEAK (show TNFSF12 Antibodies) (tumor necrosis factor (show TNF Antibodies)-like weak inducer of apoptosis), expressed on the membranes of HPCs and promoting their proliferation.
EGFR (show EGFR Antibodies) Del 19 may promote Fn14 and JAK1 (show JAK1 Antibodies)/STAT1 (show STAT1 Antibodies) expression in NSCLC.
TWEAK (show TNFSF12 Antibodies)/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation
The results demonstrated that vitreous fluid from patients with PDR had higher levels of TWEAK and Fn14 than that from T2DM patients without PDR, thus suggesting an important regulatory role of TWEAK/Fn14 signaling in the pathogenesis of PDR.
Results indicate that FN14 and GRP94 (show HSP90B1 Antibodies) are prediction/prognosis markers which open up new possibilities for preventing/treating brain metastasis in breast cancer patients.
Evidence that higher tumor Fn14 expression is required for pharmacodynamic response to the anti-TWEAK (show TNFSF12 Antibodies) monoclonal antibody RG7212 in patients with Fn14-positive solid tumors.
Fn14 has multiple roles in tumor metastasis. (Review)
TWEAK (show TNFSF12 Antibodies)/Fn14 interaction promotes oxidative stress through NADPH oxidase (show NOX1 Antibodies) activation in macrophages.
Activated Fn14 expression increases extracellular matrix synthesis and fibroblast activation. Activation of Fn14 is done by the TGF-beta (show TGFB1 Antibodies) signaling pathway through the transcription factor SMAD4 (show SMAD4 Antibodies).
TWEAK (show TNFSF12 Antibodies)/Fn14 interactions play an important role in the pathogenesis of neuropsychiatric lupus by increasing the accumulation of inflammatory cells in the choroid plexus, disrupting blood brain barrier integrity, and increasing neuronal damage
TWEAK (show TNFSF12 Antibodies)/Fn14 signaling is strongly implicated in the pathogenesis of the cutaneous manifestations in the MRL/lpr (show FAS Antibodies) model of spontaneous lupus in mice.
In SOD1 (show SOD1 Antibodies) and Neurotomized mice the results of this studysuggest LC3 (show MAP1LC3A Antibodies), Fn14, Bcl3 (show BCL3 Antibodies) and Gadd45a (show GADD45A Antibodies) as candidate genes involved in the maintenance of the severe atrophic state.
Fn14 mediates wound-healing responses that are necessary to survive acute liver injury during alcohol exposure.
Overexpression of Dnmt3a (show DNMT3A Antibodies) inhibits the gene expression of Fn14 and attenuates skeletal muscle atrophy upon denervation. Denervation also causes the activation of ERK1/2 (show MAPK1/3 Antibodies), JNK1 (show MAPK8 Antibodies)/2, and ERK5 (show MAPK7 Antibodies) MAPKs and AP1 (show JUN Antibodies) and SP1 (show SP1 Antibodies).
TWEAK (show TNFSF12 Antibodies)-FN14 signaling is necessary for the healthy adult liver to regenerate normally after acute partial hepatectomy.
The levels of TWEAK receptor Fn14 are increased in skeletal muscle during aging. Deletion of Fn14 attenuates age-associated skeletal muscle fiber atrophy.
this study showed that the apoptosis signal-regulating kinase 1 (ASK1 (show MAP3K5 Antibodies))-JNK1 (show MAPK8 Antibodies)/2 pathway, which was activated by large magnitude mechanical stretch induced expression of Fn14 gene in osteoblasts.
a model in which constitutive down-regulation of Fn14 facilitates dynamic regulation of Fn14 protein levels and prevents spontaneous or inappropriate receptor signaling.
study demonstrates that TWEAK (show TNFSF12 Antibodies) induces muscle atrophy through repressing the levels of PGC-1alpha (show PPARGC1A Antibodies)
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
, fibroblast growth factor-inducible immediate-early response protein 14
, tumor necrosis factor receptor superfamily member 12A
, type I transmembrane protein Fn14
, fibroblast growth factor regulated protein 2
, fibroblast growth factor-regulated protein 2
, fibroblast growth factor-inducible 14