Browse our anti-TNFRSF12A (TNFRSF12A) Antibodies

Full name:
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A Antibodies (TNFRSF12A)
On are 104 Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies from 24 different suppliers available. Additionally we are shipping TNFRSF12A Proteins (26) and TNFRSF12A Kits (18) and many more products for this protein. A total of 150 TNFRSF12A products are currently listed.
AI255180, C87282, CD266, Fn14, HPIP, TWEAK-R, TweakR
list all antibodies Gene Name GeneID UniProt
TNFRSF12A 51330 Q9NP84
TNFRSF12A 27279 Q9CR75
TNFRSF12A 302965  

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anti-Human TNFRSF12A Antibodies:

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anti-Rat (Rattus) TNFRSF12A Antibodies:

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Top referenced anti-TNFRSF12A Antibodies

  1. Human Monoclonal TNFRSF12A Primary Antibody for FACS, CyTOF - ABIN2661016 : Lynch, Wang, Lund, Chen, Leal, Wiley: TWEAK induces angiogenesis and proliferation of endothelial cells. in The Journal of biological chemistry 1999 (PubMed)
    Show all 7 references for 2661016

  2. Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663248 : Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 7 references for 2663248

  3. Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663247 : Feng, Guo, Factor, Thorgeirsson, Bell, Testa, Peifley, Winkles: The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. in The American journal of pathology 2000 (PubMed)
    Show all 6 references for 2663247

  4. Human Polyclonal TNFRSF12A Primary Antibody for WB - ABIN252585 : Chorianopoulos, Heger, Lutz, Frank, Bea, Katus, Frey: FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK. in Basic research in cardiology 2010 (PubMed)

More Antibodies against TNFRSF12A Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) interaction partners

  1. TWEAK (show TNFSF12 Antibodies) upregulated the expression of Fn14.

  2. Fn14.TRAIL can be converted into a highly effective TRAIL oligomer upon binding to TWEAK (show TNFSF12 Antibodies) which induces lymphoblast apoptosis.

  3. Data show that aurintricarboxylic acid (ATA) targets the TNF-related WEAK inducer of apoptosis (TWEAK (show TNFSF12 Antibodies))-fibroblast growth factor-inducible 14 (show DDX3X Antibodies) (Fn14) signaling axis, which could potentially be developed as a new therapeutic agent for treatment of glioblastoma (GBM) patients.

  4. TNFRSF12A was knocked down in the SMMC7721 cell line through siRNA. This demonstrated that cells exhibited reduced reproductive and metastatic capacity ex vivo.

  5. In this review article, we summarize studies indicating that (i) Fn14 gene expression is low in normal brain tissue but is upregulated in advanced brain cancers and, in particular, in GB tumors ; TWEAK (show TNFSF12 Antibodies): Fn14 engagement as well as Fn14 overexpression can stimulate glioma cell migration, invasion and resistance to chemotherapeutic agents in vitro.

  6. Fn14 is a receptor of mitogen TWEAK (show TNFSF12 Antibodies) (tumor necrosis factor (show TNF Antibodies)-like weak inducer of apoptosis), expressed on the membranes of HPCs and promoting their proliferation.

  7. EGFR (show EGFR Antibodies) Del 19 may promote Fn14 and JAK1 (show JAK1 Antibodies)/STAT1 (show STAT1 Antibodies) expression in NSCLC.

  8. TWEAK (show TNFSF12 Antibodies)/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation

  9. The results demonstrated that vitreous fluid from patients with PDR had higher levels of TWEAK and Fn14 than that from T2DM patients without PDR, thus suggesting an important regulatory role of TWEAK/Fn14 signaling in the pathogenesis of PDR.

  10. Results indicate that FN14 and GRP94 (show HSP90B1 Antibodies) are prediction/prognosis markers which open up new possibilities for preventing/treating brain metastasis in breast cancer patients.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) interaction partners

  1. TWEAK (show TNFSF12 Antibodies)/Fn14 interactions play an important role in the pathogenesis of neuropsychiatric lupus by increasing the accumulation of inflammatory cells in the choroid plexus, disrupting blood brain barrier integrity, and increasing neuronal damage

  2. TWEAK (show TNFSF12 Antibodies)/Fn14 signaling is strongly implicated in the pathogenesis of the cutaneous manifestations in the MRL/lpr (show FAS Antibodies) model of spontaneous lupus in mice.

  3. In SOD1 (show SOD1 Antibodies) and Neurotomized mice the results of this studysuggest LC3 (show MAP1LC3A Antibodies), Fn14, Bcl3 (show BCL3 Antibodies) and Gadd45a (show GADD45A Antibodies) as candidate genes involved in the maintenance of the severe atrophic state.

  4. Fn14 mediates wound-healing responses that are necessary to survive acute liver injury during alcohol exposure.

  5. Overexpression of Dnmt3a (show DNMT3A Antibodies) inhibits the gene expression of Fn14 and attenuates skeletal muscle atrophy upon denervation. Denervation also causes the activation of ERK1/2 (show MAPK1/3 Antibodies), JNK1 (show MAPK8 Antibodies)/2, and ERK5 (show MAPK7 Antibodies) MAPKs and AP1 (show JUN Antibodies) and SP1 (show SP1 Antibodies).

  6. TWEAK (show TNFSF12 Antibodies)-FN14 signaling is necessary for the healthy adult liver to regenerate normally after acute partial hepatectomy.

  7. The levels of TWEAK receptor Fn14 are increased in skeletal muscle during aging. Deletion of Fn14 attenuates age-associated skeletal muscle fiber atrophy.

  8. this study showed that the apoptosis signal-regulating kinase 1 (ASK1 (show MAP3K5 Antibodies))-JNK1 (show MAPK8 Antibodies)/2 pathway, which was activated by large magnitude mechanical stretch induced expression of Fn14 gene in osteoblasts.

  9. a model in which constitutive down-regulation of Fn14 facilitates dynamic regulation of Fn14 protein levels and prevents spontaneous or inappropriate receptor signaling.

  10. study demonstrates that TWEAK (show TNFSF12 Antibodies) induces muscle atrophy through repressing the levels of PGC-1alpha (show PPARGC1A Antibodies)

TNFRSF12A Antigen Profile

Antigen Summary

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Alternative names and synonyms associated with TNFRSF12A

  • tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) antibody
  • tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a) antibody
  • AI255180 antibody
  • C87282 antibody
  • CD266 antibody
  • Fn14 antibody
  • HPIP antibody
  • TWEAK-R antibody
  • TweakR antibody

Protein level used designations for TNFRSF12A

FGF-inducible 14 , fibroblast growth factor-inducible immediate-early response protein 14 , tumor necrosis factor receptor superfamily member 12A , tweak-receptor , type I transmembrane protein Fn14 , fibroblast growth factor regulated protein 2 , fibroblast growth factor-regulated protein 2 , fibroblast growth factor-inducible 14

51330 Homo sapiens
27279 Mus musculus
610734 Canis lupus familiaris
100217390 Sus scrofa
302965 Rattus norvegicus
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