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Browse our anti-TNFRSF12A (TNFRSF12A) Antibodies

Full name:
anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A Antibodies (TNFRSF12A)
On are 99 Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies from 21 different suppliers available. Additionally we are shipping TNFRSF12A Proteins (20) and TNFRSF12A Kits (11) and many more products for this protein. A total of 132 TNFRSF12A products are currently listed.
AI255180, C87282, CD266, Fn14, HPIP, TWEAK-R, TweakR
list all antibodies Gene Name GeneID UniProt
TNFRSF12A 51330 Q9NP84
TNFRSF12A 27279 Q9CR75
TNFRSF12A 302965  

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Most Popular Reactivities for anti-TNFRSF12A (TNFRSF12A) Antibodies

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anti-Human TNFRSF12A Antibodies:

anti-Mouse (Murine) TNFRSF12A Antibodies:

anti-Rat (Rattus) TNFRSF12A Antibodies:

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Top referenced anti-TNFRSF12A Antibodies

  1. Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663248 : Lynch, Wang, Lund, Chen, Leal, Wiley: TWEAK induces angiogenesis and proliferation of endothelial cells. in The Journal of biological chemistry 1999 (PubMed)
    Show all 7 references for ABIN2663248

  2. Human Monoclonal TNFRSF12A Primary Antibody for FACS, CyTOF - ABIN2661016 : Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 7 references for ABIN2661016

  3. Human Monoclonal TNFRSF12A Primary Antibody for FACS - ABIN2663247 : Feng, Guo, Factor, Thorgeirsson, Bell, Testa, Peifley, Winkles: The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. in The American journal of pathology 2000 (PubMed)
    Show all 6 references for ABIN2663247

  4. Human Polyclonal TNFRSF12A Primary Antibody for EIA, IHC (p) - ABIN499851 : Brown, Richards, Hanscom, Feng, Winkles: The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. in The Biochemical journal 2003 (PubMed)
    Show all 4 references for ABIN499851

More Antibodies against TNFRSF12A Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) interaction partners

  1. Fn14 has multiple roles in tumor metastasis. (Review)

  2. TWEAK (show TNFSF12 Antibodies)/Fn14 interaction promotes oxidative stress through NADPH oxidase (show NOX1 Antibodies) activation in macrophages.

  3. Activated Fn14 expression increases extracellular matrix synthesis and fibroblast activation. Activation of Fn14 is done by the TGF-beta (show TGFB1 Antibodies) signaling pathway through the transcription factor SMAD4 (show SMAD4 Antibodies).

  4. Fn14 modulates cell growth and drug resistance by upregulating Bcl-xl (show BCL2L1 Antibodies) expression through the NF-kappaB (show NFKB1 Antibodies) pathway.

  5. Results indicate that oncogenic Src (show SRC Antibodies) may contribute to Fn14 overexpression in solid tumors, and that Src (show SRC Antibodies) mediated cell invasion could potentially be inhibited with Fn14- targeted therapeutics.

  6. HPV type 16 infections keratinocytes turns from apoptosis to proliferation cycle under FN14 protein influence.

  7. The first human data to show a transient activation of the TWEAK (show TNFSF12 Antibodies)-Fn14 axis.

  8. TWEAK (show TNFSF12 Antibodies)-Fn14 axis may be involved in the pathogenesis of polymyositis and dermatomyositis

  9. TweakR protein was expressed in about half of human breast cancer samples

  10. Results position TWEAK (show TNFSF12 Antibodies)-Fn14 signaling through Mcl-1 (show MCL1 Antibodies) as a significant mechanism for NSCLC tumor cell survival

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) interaction partners

  1. TWEAK (show TNFSF12 Antibodies)/Fn14 interactions play an important role in the pathogenesis of neuropsychiatric lupus by increasing the accumulation of inflammatory cells in the choroid plexus, disrupting blood brain barrier integrity, and increasing neuronal damage

  2. TWEAK (show TNFSF12 Antibodies)/Fn14 signaling is strongly implicated in the pathogenesis of the cutaneous manifestations in the MRL/lpr (show FAS Antibodies) model of spontaneous lupus in mice.

  3. In SOD1 (show SOD1 Antibodies) and Neurotomized mice the results of this studysuggest LC3 (show MAP1LC3A Antibodies), Fn14, Bcl3 (show BCL3 Antibodies) and Gadd45a (show GADD45A Antibodies) as candidate genes involved in the maintenance of the severe atrophic state.

  4. Fn14 mediates wound-healing responses that are necessary to survive acute liver injury during alcohol exposure.

  5. Overexpression of Dnmt3a (show DNMT3A Antibodies) inhibits the gene expression of Fn14 and attenuates skeletal muscle atrophy upon denervation. Denervation also causes the activation of ERK1/2 (show MAPK1/3 Antibodies), JNK1 (show MAPK8 Antibodies)/2, and ERK5 (show MAPK7 Antibodies) MAPKs and AP1 (show JUN Antibodies) and SP1 (show SP1 Antibodies).

  6. TWEAK (show TNFSF12 Antibodies)-FN14 signaling is necessary for the healthy adult liver to regenerate normally after acute partial hepatectomy.

  7. The levels of TWEAK receptor Fn14 are increased in skeletal muscle during aging. Deletion of Fn14 attenuates age-associated skeletal muscle fiber atrophy.

  8. this study showed that the apoptosis signal-regulating kinase 1 (ASK1 (show MAP3K5 Antibodies))-JNK1 (show MAPK8 Antibodies)/2 pathway, which was activated by large magnitude mechanical stretch induced expression of Fn14 gene in osteoblasts.

  9. a model in which constitutive down-regulation of Fn14 facilitates dynamic regulation of Fn14 protein levels and prevents spontaneous or inappropriate receptor signaling.

  10. study demonstrates that TWEAK (show TNFSF12 Antibodies) induces muscle atrophy through repressing the levels of PGC-1alpha (show PPARGC1A Antibodies)

TNFRSF12A Antigen Profile

Antigen Summary

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Alternative names and synonyms associated with TNFRSF12A

  • tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) antibody
  • tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a) antibody
  • AI255180 antibody
  • C87282 antibody
  • CD266 antibody
  • Fn14 antibody
  • HPIP antibody
  • TWEAK-R antibody
  • TweakR antibody

Protein level used designations for TNFRSF12A

FGF-inducible 14 , fibroblast growth factor-inducible immediate-early response protein 14 , tumor necrosis factor receptor superfamily member 12A , tweak-receptor , type I transmembrane protein Fn14 , fibroblast growth factor regulated protein 2 , fibroblast growth factor-regulated protein 2 , fibroblast growth factor-inducible 14

51330 Homo sapiens
27279 Mus musculus
610734 Canis lupus familiaris
100217390 Sus scrofa
302965 Rattus norvegicus
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