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anti-Mouse (Murine) TNFRSF12A antibody for Functional Studies

Recommended TNFRSF12A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
  • CD266
  • FN14
  • TWEAKR
  • AI255180
  • C87282
  • Fn14
  • HPIP
  • TWEAK-R
  • TweakR
  • tumor necrosis factor receptor superfamily, member 12A
  • tumor necrosis factor receptor superfamily, member 12a
  • TNFRSF12A
  • Tnfrsf12a
Reactivity
Human, Mouse (Murine)
92
42
24
Host
Mouse
49
44
3
1
Clonality
Monoclonal
Conjugate
This TNFRSF12A antibody is un-conjugated
10
6
4
2
2
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Western Blotting (WB)
53
44
20
17
15
11
11
8
3
2
2
1
1
1
1
1
Options
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Catalog No. ABIN2749025
$ 231.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2749054 Func IHC (f) FACS WB Mouse IgG2b Log in to see ITEM-4 3
1 ABIN2749122 Func IHC (f) FACS WB PE Mouse IgG2b Log in to see ITEM-4 3
1 ABIN3199692 FACS Func IHC (fro) WB PE Mouse IgG2b Log in to see ITEM-4
1 ABIN3199690 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4
1 ABIN3199691 FACS Func IHC (fro) WB Mouse IgG2b Log in to see ITEM-4
1 ABIN3037011 Func FACS IHC WB Mouse IgG2b Log in to see
1 ABIN3037013 Func FACS IHC WB PE Mouse IgG2b Log in to see
1 ABIN2142027 Func ELISA Mouse IgG2b kappa Log in to see ITEM-4
1 ABIN3037012 Func FACS IHC WB Mouse IgG2b Log in to see

Top referenced anti-TNFRSF12A antibody for Functional Studies

Similar anti-TNFRSF12A Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 6 Antibodies 16 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 21 Antibodies 41 Antibodies
Functional Studies (Func) 10 Antibodies 12 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 8 Antibodies 18 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Western Blotting (WB) 21 Antibodies
Blocking Reagent (BR) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (IF) 2 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antibodies
Reactivity Human, Mouse (Murine)
(92), (42), (24)
Host Mouse
(49), (44), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF12A antibody is un-conjugated
(10), (6), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Western Blotting (WB)
(53), (44), (20), (17), (15), (11), (11), (8), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-TNFRSF12A Antibody

Target Details TNFRSF12A Application Details Handling References for anti-TNFRSF12A Antibody (ABIN2749025) Images
Specificity The mouse monoclonal antibody ITEM-4 recognizes CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
Purification Purified from cell culture supernatant by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
Immunogen human CD266-transfected P815 cells
Clone ITEM-4
Isotype IgG2b

Target Details TNFRSF12A

Product Details anti-TNFRSF12A Antibody Application Details Handling References for anti-TNFRSF12A Antibody (ABIN2749025) Images back to top
Antigen
Alternative Name CD266 / TWEAK R (TNFRSF12A Antibody Abstract)
Background CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Pathways Apoptosis

Application Details

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Handling References for anti-TNFRSF12A Antibody (ABIN2749025) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details References for anti-TNFRSF12A Antibody (ABIN2749025) Images back to top
Buffer Azide free phosphate buffered saline (PBS), approx. pH 7.4
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-TNFRSF12A Antibody (ABIN2749025)

Product Details anti-TNFRSF12A Antibody Target Details TNFRSF12A Application Details Handling Images back to top
Product cited in:

Yoriki, Akashi, Sho, Nomi, Yamato, Hotta, Takayama, Matsumoto, Wakatsuki, Migita, Yagita, Nakajima: "Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer." in: Experimental and therapeutic medicine, Vol. 2, Issue 1, pp. 103-108, 2012

Roos, Wicovsky, Müller, Salzmann, Rosenthal, Kalthoff, Trauzold, Seher, Henkler, Kneitz, Wajant: "Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1593-605, 2010

Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: "Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 341-8, 2002