anti-Human TNFRSF25 antibody for Immunocytochemistry

Recommended TNFRSF25 Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibodies
  • TNFRSF25
  • APO-3
  • DDR3
  • DR3
  • LARD
  • TNFRSF12
  • TR3
  • TRAMP
  • WSL-1
  • WSL-LR
  • Tnfrsf12
  • Wsl
  • tumor necrosis factor receptor superfamily, member 25
  • TNFRSF25
  • Tnfrsf25
Epitope
Extracellular Domain
23
15
15
14
14
14
13
11
11
9
6
5
4
4
3
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine)
221
99
36
3
2
2
2
2
1
1
Host
Rabbit
152
75
4
1
Clonality
Polyclonal
Conjugate
This TNFRSF25 antibody is un-conjugated
14
10
6
6
5
5
5
4
4
4
4
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
129
65
58
26
23
20
11
8
6
5
2
2
2
1
1
Supplier
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Catalog No. ABIN1002203
$ 466.62
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1733767 ICC IHC (p) ELISA WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
1 ABIN343910 ICC IHC (p) ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN4306228 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN5076381 ICC IF Rabbit IgG Log in to see Polyclonal
1 ABIN1030835 ICC ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN1101200 ICC WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
1 ABIN1733763 ICC WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
1 ABIN1887794 ICC ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN1583638 ICC ELISA WB Rabbit Log in to see Polyclonal
1 ABIN2768569 ICC IHC (p) IHC ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibodies
Epitope Extracellular Domain
(23), (15), (15), (14), (14), (14), (13), (11), (11), (9), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine)
(221), (99), (36), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(152), (75), (4), (1)
Clonality
Polyclonal
Conjugate This TNFRSF25 antibody is un-conjugated
(14), (10), (6), (6), (5), (5), (5), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(129), (65), (58), (26), (23), (20), (11), (8), (6), (5), (2), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-TNFRSF25 Antibody

Target Details TNFRSF25 Application Details Handling References for anti-TNFRSF25 antibody (ABIN1002203) Images
Blocking Peptide Blocking peptide for this product available: ABIN1003922
Purification Antibody is purified via DEAE-column chromatography.
Immunogen Rabbit polyclol DR3 antibody was raised against a peptide corresponding to amino acids in extracellular domain (ED) of human DR3 precusor.
Isotype IgG

Target Details TNFRSF25

Product Details anti-TNFRSF25 Antibody Application Details Handling References for anti-TNFRSF25 antibody (ABIN1002203) Images back to top
Antigen
Alternative Name Death Receptor 3 (TNFRSF25 Antibody Abstract)
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.
Pathways Apoptosis

Application Details

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Handling References for anti-TNFRSF25 antibody (ABIN1002203) Images back to top
Application Notes DR3 antibody can be used for detection of DR3 expression by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user.) Jurkat total cell lysate can be used as positive control and a 59 kDa band should be detected. Antibody can also be used for immunocytochemistry and ELISA and might be suited for other applications not tested so far. DR3 antibody is human and mouse reactive.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details References for anti-TNFRSF25 antibody (ABIN1002203) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-TNFRSF25 antibody (ABIN1002203)

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details Handling Images back to top
Product cited in:

Marsters, Sheridan, Donahue, Pitti, Gray, Goddard, Bauer, Ashkenazi: "Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B." in: Current biology : CB, Vol. 6, Issue 12, pp. 1669-76, 1997

Bodmer, Burns, Schneider, Hofmann, Steiner, Thome, Bornand, Hahne, Schröter, Becker, Wilson, French, Browning, MacDonald, Tschopp: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, 1997

Background publications

Chinnaiyan, ORourke, Yu, Lyons, Garg, Duan, Xing, Gentz, Ni, Dixit: "Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95." in: Science (New York, N.Y.), Vol. 274, Issue 5289, pp. 990-2, 1996

Kitson, Raven, Jiang, Goeddel, Giles, Pun, Grinham, Brown, Farrow: "A death-domain-containing receptor that mediates apoptosis." in: Nature, Vol. 384, Issue 6607, pp. 372-5, 1996