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anti-Mouse (Murine) TNFRSF25 antibody for Blocking Reagent

Recommended TNFRSF25 Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibodies
  • APO-3
  • DDR3
  • DR3
  • LARD
  • Tnfrsf12
  • TNFRSF12
  • TNFRSF25
  • TR3
  • TRAMP
  • Wsl
  • WSL-1
  • WSL-LR
Reactivity
Mouse (Murine)
172
60
28
2
Host
Armenian Hamster
145
33
3
1
Clonality
Monoclonal
Conjugate
This TNFRSF25 antibody is un-conjugated
11
10
4
4
2
2
2
2
2
2
2
2
2
2
2
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Mass Cytometry (CyTOF), Immunohistochemistry (IHC)
123
60
22
22
22
17
10
6
5
2
1
1
1
1
1
Supplier
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Catalog No. ABIN2665775
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008709465 ABIN2665774 BR FACS CyTOF IHC Armenian Hamster IgG Log in to see 4C12 6

Top referenced anti-TNFRSF25 antibody for Blocking Reagent

Similar anti-TNFRSF25 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies
ELISA 19 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Western Blotting (WB) 47 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibodies
Reactivity Mouse (Murine)
(172), (60), (28), (2)
Host Armenian Hamster
(145), (33), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF25 antibody is un-conjugated
(11), (10), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Mass Cytometry (CyTOF), Immunohistochemistry (IHC)
(123), (60), (22), (22), (22), (17), (10), (6), (5), (2), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-TNFRSF25 Antibody

Target Details TNFRSF25 Application Details Handling References for anti-TNFRSF25 Antibody (ABIN2665775) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone 4C12
Isotype IgG

Target Details TNFRSF25

Product Details anti-TNFRSF25 Antibody Application Details Handling References for anti-TNFRSF25 Antibody (ABIN2665775) Images back to top
Antigen
Alternative Name DR3 (TNFRSF25 Antibody Abstract)
Background DR3, also known as TNFRSF25, lymphocyte-associated receptor of death (LARD), WSL-1, TRAMP, TR3 and APO3, is a 55 kD glycoprotein belonging to the TNF receptor superfamily (TNFRSF). TNFSF25 is expressed at low level on CD4-positive, CD8-positive T cells and NKT cells. It has been shown to stimulate NF-κB activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domains containing adaptor proteins. Recently, it has been shown that TNFRSF25 is also expressed on Treg cells and regulates Treg proliferation.
Research Area Signaling, Apoptosis/Necrosis, Death Receptors, Major Histocompatibility Complex (MHC)
Pathways Apoptosis

Application Details

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Handling References for anti-TNFRSF25 Antibody (ABIN2665775) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details References for anti-TNFRSF25 Antibody (ABIN2665775) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF25 Antibody (ABIN2665775)

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details Handling Images back to top
Background publications

Longman, Diehl, Victorio, Huh, Galan, Miraldi, Swaminath, Bonneau, Scherl, Littman: "CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22." in: The Journal of experimental medicine, Vol. 211, Issue 8, pp. 1571-83, 2014

Schreiber, Wolf, Bodero, Gonzalez, Podack: "T cell costimulation by TNFR superfamily (TNFRSF)4 and TNFRSF25 in the context of vaccination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3311-8, 2012

Taraban, Ferdinand, Al-Shamkhani: "Expression of TNFRSF25 on conventional T cells and Tregs." in: The Journal of clinical investigation, Vol. 121, Issue 2, pp. 463-4; author reply 465, 2011

Slebioda, Rowley, Ferdinand, Willoughby, Buchan, Taraban, Al-Shamkhani: "Triggering of TNFRSF25 promotes CD8⁺ T-cell responses and anti-tumor immunity." in: European journal of immunology, Vol. 41, Issue 9, pp. 2606-11, 2011

Schreiber, Wolf, Tsai, Chirinos, Deyev, Gonzalez, Malek, Levy, Podack: "Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation." in: The Journal of clinical investigation, Vol. 120, Issue 10, pp. 3629-40, 2010

Fang, Adkins, Deyev, Podack: "Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation." in: The Journal of experimental medicine, Vol. 205, Issue 5, pp. 1037-48, 2008

Images

Product Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details Handling References for anti-TNFRSF25 Antibody (ABIN2665775) back to top
Supplier Images
ELISA image for anti-TNFRSF25 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 25) (ABIN2665775) anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) antibody
Flow Cytometry (FACS) image for anti-TNFRSF25 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 25) (ABIN2665775) anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) antibody (Image 2)