You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human XIAP antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended XIAP Antibody (supplied by: Log in to see )

Antigen
X-Linked Inhibitor of Apoptosis (XIAP) Antibodies
  • 1110015C02Rik
  • Aipa
  • Api3
  • API3
  • api3
  • birc4
  • Birc4
  • BIRC4
  • hIAP-3
  • hIAP3
  • IAP-3
  • IAP3
  • ILP-1
  • ILP1
  • ilp1
  • MIHA
  • miha
  • mXIAP
  • riap3
  • xlp2
  • XLP2
  • xxiap
Epitope
C-Term
26
21
13
8
7
6
5
5
4
4
4
3
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
156
54
36
6
4
4
2
2
Host
Rabbit
138
23
1
Clonality
Polyclonal
Conjugate
This XIAP antibody is un-conjugated
6
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
134
57
57
31
21
19
11
11
9
7
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN501135
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.33594158 ABIN615851 IF IHC (p) WB Rabbit AA 75-226 Log in to see Polyclonal
0.33594158 ABIN214586 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.00090296083 ABIN358604 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 3
0.00090296083 ABIN390070 IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 2
0.00090296083 ABIN674364 IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 230-280 Log in to see Polyclonal 3
0.00090296083 ABIN272094 IHC (p) WB Rabbit Log in to see Polyclonal
0.00090296083 ABIN127043 IHC (p) IP WB Rabbit Log in to see Polyclonal
0.00090296083 ABIN2888718 IHC (p) ELISA WB Rabbit IgG AA 53-102 Log in to see Polyclonal
0.00090296083 ABIN2854771 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.00090296083 ABIN3044425 IHC (p) WB Rabbit IgG AA 14-34, N-Term Log in to see Polyclonal
0.00090296083 ABIN303361 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.00090296083 ABIN957244 IHC (fro) IHC (p) IP WB Rabbit AA 163-230 Log in to see Polyclonal
0.00090296083 ABIN957247 IHC (fro) IHC (p) IP WB Rabbit AA 163-230 Log in to see Polyclonal
0.00090296083 ABIN957245 IHC (fro) IHC (p) IP WB Rabbit AA 163-230 Log in to see Polyclonal
0.00090296083 ABIN957248 IHC (fro) IHC (p) IP WB Rabbit AA 241-260 Log in to see Polyclonal
0.00090296083 ABIN957246 IHC (fro) IHC (p) IP WB Rabbit AA 163-230 Log in to see Polyclonal
0.00090296083 ABIN604955 ICC IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00090296083 ABIN2629888 IHC (p) WB Rabbit IgG AA 14-34 Log in to see Polyclonal
0.00090296083 ABIN674366 IHC (p) WB Biotin Rabbit IgG AA 230-280 Log in to see Polyclonal
0.00090296083 ABIN674373 IHC (p) WB HRP Rabbit IgG AA 230-280 Log in to see Polyclonal

Top referenced anti-XIAP antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-XIAP Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 13 Antibodies 53 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 9 Antibodies
Immunofluorescence (IF) 9 Antibodies 21 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 43 Antibodies
ELISA (Capture) 1 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen X-Linked Inhibitor of Apoptosis (XIAP) Antibodies
Epitope C-Term
(26), (21), (13), (8), (7), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(156), (54), (36), (6), (4), (4), (2), (2)
Host Rabbit
(138), (23), (1)
Clonality
Polyclonal
Conjugate This XIAP antibody is un-conjugated
(6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(134), (57), (57), (31), (21), (19), (11), (11), (9), (7), (3), (1), (1), (1), (1)
Pubmed 6 references available
Supplier Log in to see

Product Details anti-XIAP Antibody

Target Details XIAP Application Details Handling References for anti-XIAP Antibody (ABIN501135) Images
Specificity This antibody detects HILP, API3, XIAP at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Immunoaffinity Chromatography
Immunogen XIAP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP.
Isotype IgG

Target Details XIAP

Product Details anti-XIAP Antibody Application Details Handling References for anti-XIAP Antibody (ABIN501135) Images back to top
Antigen
Alternative Name IAP3 / BIRC4 (XIAP Antibody Abstract)
Background Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The X-chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases -3, -7, and -9 (2,3). Upregulation of XIAP expression can protect cells from apoptosis induced by low level radiation, conversely, decreased XIAP expression by antisense targeting resulted in increased cell death following low level radiation (4). Two negative regulators, termed XAF-1 (5) and Smac (6), can bind and inhibit XIAP activity.Synonyms: API3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, HILP, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein, XIAP
Gene ID 331
NCBI Accession NP_001158
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-XIAP Antibody Target Details XIAP Handling References for anti-XIAP Antibody (ABIN501135) Images back to top
Application Notes ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-XIAP Antibody Target Details XIAP Application Details References for anti-XIAP Antibody (ABIN501135) Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-XIAP Antibody (ABIN501135)

Product Details anti-XIAP Antibody Target Details XIAP Application Details Handling Images back to top
Background publications

Albaladejo, Alonso, Yus: "Synthesis of indolizines and heterocyclic chalcones catalyzed by supported copper nanoparticles." in: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 19, Issue 17, pp. 5242-5, 2013

Schimmer: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." in: Cancer research, Vol. 64, Issue 20, pp. 7183-90, 2004

Holcik, Yeh, Korneluk, Chow: "Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death." in: Oncogene, Vol. 19, Issue 36, pp. 4174-7, 2000

Deveraux, Leo, Stennicke, Welsh, Salvesen, Reed: "Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases." in: The EMBO journal, Vol. 18, Issue 19, pp. 5242-51, 1999

Deveraux, Takahashi, Salvesen, Reed: "X-linked IAP is a direct inhibitor of cell-death proteases." in: Nature, Vol. 388, Issue 6639, pp. 300-4, 1997

Fukui, Goto, Tabata: "Two antimicrobial flavanones from the leaves of Glycyrrhiza glabra." in: Chemical & pharmaceutical bulletin, Vol. 36, Issue 10, pp. 4174-6, 1989

Images

Product Details anti-XIAP Antibody Target Details XIAP Application Details Handling References for anti-XIAP Antibody (ABIN501135) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-XIAP antibody (X-Linked Inhibitor of Apoptosis) (C-Term) (ABIN501135) Immunohistochemical staining of Human kidney tissue using AP30993PU-N XIAP antibody a...
Western Blotting (WB) image for anti-XIAP antibody (X-Linked Inhibitor of Apoptosis) (C-Term) (ABIN501135) Western blot analysis of XIAP in Human kidney lysate using AP30993PU-N XIAP antibody ...