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Browse our XIAP (XIAP) ELISA Kits

Full name:
X-Linked Inhibitor of Apoptosis ELISA Kits (XIAP)
On www.antibodies-online.com are 19 X-Linked Inhibitor of Apoptosis (XIAP) ELISA Kits from 11 different suppliers available. Additionally we are shipping XIAP Antibodies (176) and XIAP Proteins (15) and many more products for this protein. A total of 225 XIAP products are currently listed.
Synonyms:
1110015C02Rik, Aipa, Api3, Birc4, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, MIHA, mXIAP, riap3, XLP2, xxiap

XIAP (XIAP) ELISA Kits by Reactivity

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Human X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. miR (show MLXIP ELISA Kits)-137 expression is inversely correlated with the level of XIAP protein in both ovarian cancer tissues and cell lines. these data suggest that multiple miRNAs can regulate XIAP via its 3'UTR (show UTS2R ELISA Kits). miR (show MLXIP ELISA Kits)-137 can sensitise ovarian cancer cells to cisplatin-induced apoptosis, providing new insight into overcoming drug resistance in ovarian cancer

  2. results of this work support the role of XIAP in mediating NOD2 (show NOD2 ELISA Kits) signaling while reconciling the role of X-linked lymphoproliferative syndrome 2 and very-early-onset inflammatory bowel disease XIAP mutations in inflammatory cell death and provide a set of tools and framework to rapidly test newly discovered XIAP variants.

  3. Using recombinant proteins, this study investigated the influence of survivin (show BIRC5 ELISA Kits) on the inhibition of caspase-9 (show CASP9 ELISA Kits) by XIAP in vitro. With a fluorescence-based assay for the apoptosome-stimulated activity of caspase-9 (show CASP9 ELISA Kits), the study shows that survivin (show BIRC5 ELISA Kits) has no effect on the inhibition of caspase-9 (show CASP9 ELISA Kits) by XIAP, neither in the presence nor in the absence of Smac (show DIABLO ELISA Kits).

  4. Study found a negative correlation between Smac (show DIABLO ELISA Kits) and XIAP at the level of protein but not mRNA in non-small cell lung carcinoma (NSCLC) patients. Overexpressed XIAP could degrade through ubiquitination, the mature Smac (show DIABLO ELISA Kits) inhibiting NSCLC apoptosis.

  5. Combined triple actions of the TRAIL, the IAPs inhibitor, AT406, and the c-FLIP (show CFLAR ELISA Kits) expression inhibitor, rocaglamide (ART), markedly improve TRAIL-induced apoptotic effects in most solid cancer cell lines through the activation of an extrinsic apoptosis pathway

  6. we identified X-linked inhibitor of apoptosis protein (XIAP) as a direct target of miR (show MLXIP ELISA Kits)-509-3p.

  7. MiR (show MLXIP ELISA Kits)-874 inhibits growth, increases apoptosis and enhances chemosensitivity in CRC (show CALR ELISA Kits) cells by targeting XIAP.

  8. Data show that X-linked inhibitor of apoptosis protein (XIAP) mRNA and protein expression increased, whereas XIAP-associated factor 1 (XAF1 (show XAF1 ELISA Kits)) mRNA and protein expression decreased with the growth of radiation dose and exposure time.

  9. We demonstrated that, while depletion of XIAP attenuates cell transformation, elevated USP11 (show USP11 ELISA Kits) significantly promotes the tumor colony formation through stabilization of XIAP.

  10. High XIAP expression is associated with ovarian cancer.

Mouse (Murine) X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. Results show that XIAP binds to the C terminus of Ptch1 (show PTCH1 ELISA Kits) and mediates the death-dependent function of Ptch1 (show PTCH1 ELISA Kits).

  2. XIAP modulates ubiquitylation of RIP1 (show RALBP1 ELISA Kits) and suppresses RIP3 (show MPRIP ELISA Kits)-dependent cell death and inflammasome activation in response to TNF (show TNF ELISA Kits)-signaling in innate immune cells.

  3. XIAP deficiency selectively impaired B-cell chronic lymphocytic leukemia/lymphoma 10 (BCL10 (show BCL10 ELISA Kits))-mediated innate responses to dectin-1 (show CLEC7A ELISA Kits) ligands but did not affect responses to various Toll (show TLR4 ELISA Kits)-like receptor agonists.

  4. XIAP mRNA level was also reduced in the BRE (show BRE ELISA Kits)-depleted cells, but the level of reduction was less profound than that of the protein level. However, BRE (show BRE ELISA Kits) could not delay protein turnover of XIAP.

  5. Identify xIAP and cIAP1 (show BIRC2 ELISA Kits) as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.

  6. XIAP-/- DRG sensory neurons degenerate more rapidly and contain more active caspase-3 (show CASP3 ELISA Kits).

  7. XIAP ubiquitylates RIPK2 (show RIPK2 ELISA Kits) and recruits the linear ubiquitin chain assembly complex to NOD2 (show NOD2 ELISA Kits)

  8. XIAP is expressed in oligodendrocytes in vivo and in vitro. Increased XIAP expression is associated with protection against selected cell death pathways, whereas decreased expression increases oligodendroglial cell death.

  9. ARTS (Septin 4 (show SEPT4 ELISA Kits)) promotes apoptosis mainly through binding and antagonizing XIAP.

  10. A critical role is identified for XIAP in regulating neuronal apoptosis in neonatal brain injury.

XIAP Antigen Profile

Antigen Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

Alternative names and synonyms associated with XIAP

  • X-linked inhibitor of apoptosis (XIAP) Elisa Kit
  • X-linked inhibitor of apoptosis (xiap) Elisa Kit
  • X-linked inhibitor of apoptosis (Xiap) Elisa Kit
  • 1110015C02Rik Elisa Kit
  • Aipa Elisa Kit
  • Api3 Elisa Kit
  • Birc4 Elisa Kit
  • hIAP-3 Elisa Kit
  • hIAP3 Elisa Kit
  • IAP-3 Elisa Kit
  • IAP3 Elisa Kit
  • ILP-1 Elisa Kit
  • ILP1 Elisa Kit
  • MIHA Elisa Kit
  • mXIAP Elisa Kit
  • riap3 Elisa Kit
  • XLP2 Elisa Kit
  • xxiap Elisa Kit

Protein level used designations for XIAP

X-linked inhibitor of apoptosis protein , baculoviral IAP repeat-containing 4 , baculoviral IAP-repeat containing protein 4 , Baculoviral IAP repeat-containing protein 4 , E3 ubiquitin-protein ligase XIAP , X-linked IAP , IAP-like protein , baculoviral IAP repeat-containing protein 4 , inhibitor of apoptosis protein 3 , IAP homolog A , IAP-3 , apoptosis inhibitor 3 , mIAP-3 , mIAP3 , RIAP-3 , apoptosis inhibitor protein 3

GENE ID SPECIES
442989 Canis lupus familiaris
594971 Xenopus (Silurana) tropicalis
331 Homo sapiens
11798 Mus musculus
63879 Rattus norvegicus
733235 Xenopus laevis
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