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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Immunofluorescence (fixed cells) (IF/ICC)||8 Antibodies||7 Antibodies||7 Antibodies|
|Western Blotting (WB)||176 Antibodies||123 Antibodies||98 Antibodies|
|Immunoprecipitation (IP)||14 Antibodies||14 Antibodies||14 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||57 Antibodies||46 Antibodies||37 Antibodies|
|Immunohistochemistry (IHC)||83 Antibodies||53 Antibodies||43 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies|
|Antigen||tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This YWHAZ antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-YWHAZ AntibodyTarget Details YWHAZ Application Details Handling Images
|Specificity||This antibody detects endogenous levels of 14-3-3 ζ protein. (region surrounding Ala79)|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purity||> 95 % by SDS-PAGE|
Target Details YWHAZProduct Details anti-YWHAZ Antibody Application Details Handling Images back to top
|Alternative Name||14-3-3 Protein zeta/delta (YWHAZ Antibody Abstract)|
|Background||14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, theta, epsilon, zeta, sigma and nu. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzyme activity etc.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAZ|
|Molecular Weight||approx. 28 kDa|
|Research Area||Transcription Factors|
|Pathways||Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location|
Application DetailsProduct Details anti-YWHAZ Antibody Target Details YWHAZ Handling Images back to top
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-YWHAZ Antibody Target Details YWHAZ Application Details Images back to top
|Buffer||Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-YWHAZ Antibody Target Details YWHAZ Application Details Handling back to top