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Studies in mouse indicate the 80 aa SMAF1 protein is involved in adipocyte tissue function or regulation.
Together our findings show that Smaf1 is a novel small protein endogenous to adipocytes and that Smaf1 expression is closely tied to PPARgamma (show PPARG Proteins)-mediated signals and the adipocyte phenotype.
Adipocyte-specific membrane protein adipogenin may be involved with adipogenesis as one of the regulators of adipose tissue development.
isolated myosatellite cells based on adhesion characteristics to investigate whether ADIG overexpression could promote trans-differentiation and increase fat accumulation in myosatellite cells
ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005
, small adipocyte factor 1
, adipogenesis associated
, small adipocyte factor 1 (SMAF1)