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Mouse (Murine) PTGS2 ELISA Kit for Sandwich ELISA - ABIN415493
Tsai, Lin, Yang, Tseng, Hsu, Lee, Cherng: Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis. in Evidence-based complementary and alternative medicine : eCAM 2012
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Rat (Rattus) PTGS2 ELISA Kit for Sandwich ELISA - ABIN457222
Uzun, Atli, Perk, Burukoglu, Ilgin: Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats. in Human & experimental toxicology 2014
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Rat (Rattus) PTGS2 ELISA Kit for Sandwich ELISA - ABIN579774
Zhang, Yu, Kang, Zhu: Effect of ω-3 fatty acid on gastrointestinal motility after abdominal operation in rats. in Mediators of inflammation 2011
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Human PTGS2 ELISA Kit for Sandwich ELISA - ABIN417176
Li, Wang, Su, Li, Gong: Monitoring of cyclooxygenase-2 levels can predict EGFR mutations and the efficacy of EGFR-TKI in patients with lung adenocarcinoma. in International journal of clinical and experimental pathology 2015
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Rat (Rattus) PTGS2 ELISA Kit for Sandwich ELISA - ABIN416415
Yang, Yuan, Chen, Xiong, Ruan: Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. in Journal of ethnopharmacology 2013
Human PTGS2 ELISA Kit for Sandwich ELISA - ABIN365070
Salvolini, Buldreghini, Lucarini, Vignini, Giulietti, Lenzi, Mazzanti, Di Primio, Balercia: Interleukin-1β, cyclooxygenase-2, and hypoxia-inducible factor-1α in asthenozoospermia. in Histochemistry and cell biology 2014
This study showed that COX-1 (show PTGS1 ELISA Kits) and COX-2 in genital carcinomas in the horse is poor; microsomal PGES (show PTGES ELISA Kits)-1 is more prominently expressed.
Progestin treatment does not affect expression of cytokines, steroid receptors, oxytocin receptor (show OXTR ELISA Kits), and cyclooxygenase 2 in fetal membranes and endometrium.
COX-1 (show PTGS1 ELISA Kits) and COX-2 genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 gene expression at each subsequent time point, compared with baseline values.
The role for p38 (show MAPK14 ELISA Kits) mitogen-activated kinase (MAPK (show MAPK1 ELISA Kits)) in the signaling mechanism regulating pro-inflammatory cyclooxygenase (COX (show CPOX ELISA Kits)) gene expression in lipopolysaccharide (LPS (show IRF6 ELISA Kits))-activated equine leukocytes in horses is reported.
In this study, both COX-1 (show PTGS1 ELISA Kits) and COX-2 were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2.
Immunoreactivity for COX-1 (show PTGS1 ELISA Kits) and COX-2 is high in equine corneal SCC (show CYP11A1 ELISA Kits), possibly indicating that COX (show CPOX ELISA Kits) plays a role in oncogenesis or progression of this tumor type at this site.
It was found that most equine squamous-cell carcinomas and many melanomas appear to express COX-2 and thus could respond to COX-2 inhibitor therapy.
data support the hypothesis that prostaglandin G/H synthase 2(PGHS2)is a target for the antiluteolytic signal produced by equine conceptuses during early pregnancy
The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis.
results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha (show NR1D1 ELISA Kits)) plays an inhibitory role in the expression of prostaglandin-endoperoxide synthase 2(PTGS2) in both bovine USCs and UECs treated with ovarian steroids
This study showed that neutrophils from periparturient heifers show impairment of COX-2 mRNA expression and lactoferrin (show LTF ELISA Kits), suggesting that these mechanisms may contribute to immunosuppression in cows around calving.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 ELISA Kits) and PTGS2, and decreased the expression of SOD2 (show SOD2 ELISA Kits), GPX3 (show GPX3 ELISA Kits), DAB2 (show DAB2 ELISA Kits), and NR3C1 (show NR3C1 ELISA Kits). TNF (show TNF ELISA Kits) and IL6 (show IL6 ELISA Kits) levels were also decreased while those of NAMPT (show NAMPT ELISA Kits) were unaffected.
Purinergic P2Y1 receptor (show P2RY1 ELISA Kits) signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts
Data suggest that Escherichia coli infections (here, administration of LPS (show IRF6 ELISA Kits)) provokes luteolysis in diestrus, non-lactating cows but no change in expression of PTGS2 in corpus luteum and has no effect on luteinization in the following cycle.
This study is the first to report the involvement of PGE2 in oocyte MAPK (show MAPK1 ELISA Kits) activation during the maturation process.
Inhibitors of c-Src (show SRC ELISA Kits) (PP2, 10 microm) and PI3K (LY294002, 25 microm) produced a significant decrease in oxytocin-induced PGF (show PGF ELISA Kits)(2 alpha) production and reduced COX2 expression by endometrial epithelial cells.
COX-2 pathway is responsible for the endometrial production of PGE (show LIPF ELISA Kits)(2) in the bovine endometrium during the estrous cycle
the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 and GM-CSF (show CSF2 ELISA Kits) during the peri (show PLIN1 ELISA Kits)-attachment period in the cow.
Angiotensin II-AT1-receptor (show AGTRAP ELISA Kits) signaling is necessary for COX-2 (show COX2 ELISA Kits)-dependent normal postnatal nephrogenesis and maturation.
AhR (show AHR ELISA Kits) controls COX-2 (show COX2 ELISA Kits) protein via mRNA stability.
Podocyte-specific knockout of COX2 (show COX2 ELISA Kits) enhanced albuminuria and did not attenuate the histologic features of diabetic kidney disease.
Salt supplementation during the COX-2 (show COX2 ELISA Kits)-dependent time frame of nephrogenesis partly reverses renal morphological defects in COX-2 (show COX2 ELISA Kits)(-/-) mice and improves kidney function.
Data suggest that induction of Ptgs2 expression in preimplantation uterus may be earliest positive embryo/blastocyst signal for implantation and pregnancy recognition in mice.
the bone regeneration capacity of Cox (show CPOX ELISA Kits)-2KO MDSCs was impaired because of a reduction in cell proliferation and survival capacities, reduction in osteogenic differentiation and a decrease in the ability of the cells to recruit host cells to the injury site.
these studies have demonstrated an important but unexpected role for macrophage COX-2 (show COX2 ELISA Kits)/prostaglandin E2/PGE2 receptor subtype 4 signaling to lessen progression of diabetic kidney disease, unlike the pathogenic effects of increased COX-2 (show COX2 ELISA Kits) expression in intrinsic renal cells.
Data (including data from studies using knockout/mutant mice) suggest that Mir200c (microRNA 200c) is involved in endothelial function/dysfunction via regulation of Cox2 (cyclooxygenase-2) expression; overexpression of Mir200c impairs endothelium-dependent vascular relaxation (EDVR) in non-diabetic mouse aorta, whereas suppression of Mir200c by anti-Mir200c enhances EDVR in diabetic mouse aorta.
data indicate that excessive adipocyte lipolysis activates the JNK (show MAPK8 ELISA Kits)/NFkappaB pathway leading to the up-regulation of COX-2 (show COX2 ELISA Kits) expression and recruitment of inflammatory macrophages.
this study shows that c-Jun (show JUN ELISA Kits) regulates the activation state of macrophages and promotes arthritis via differentially regulating cyclooxygenase-2 and arginase-1 (show ARG1 ELISA Kits) levels
that a genetically modulated balancing of signaling within the CB1 (show CNR1 ELISA Kits)-COX-2 (show COX2 ELISA Kits) pathway may reflect on more or less efficient patterns of prefrontal activity during working memory
Diabetes and cardiopulmonary bypass are associated with upregulation in COX-2 (show COX2 ELISA Kits) expression/activation in peripheral microvasculature.
COX-2 (show COX2 ELISA Kits) directly oxidizes 2-arachidonoyl-lysophospholipids to eicosanoid-lysolipids.
COX-2 (show COX2 ELISA Kits) is a potential marker for identifying high-risk sebaceous gland carcinoma (SGC (show SGCB ELISA Kits)) patients. Expression of PPAR-gamma (show PPARG ELISA Kits) in eyelid SGC (show SGCB ELISA Kits) cases reflects terminal sebaceous differentiation.
COX-2 (show COX2 ELISA Kits) expression correlates with and modulates PD-L1 (show CD274 ELISA Kits) expression in melanoma cells.
PTGS2 rs20417CC genotype is associated with carotid plaque vulnerability, platelet activation and TXA2 (show TBXA2R ELISA Kits) levels in ischemic stroke patients.
Current results suggest that COX-2 (show COX2 ELISA Kits) rs689466, rs5275, and rs20417 polymorphisms are not associated with head and neck squamous cell carcinoma.[meta-analysis]
Specific inhibitors of COX-2 (show COX2 ELISA Kits) and 5-LOX (show ALOX5 ELISA Kits) decreased formation of HKD2 and HKE2 (show PFDN6 ELISA Kits) Platelets did not form HKs from exogenous 5S-hydroxyeicosatetraenoic acid, implying that COX-1 (show COX1 ELISA Kits) is not involved
Leptin (show LEP ELISA Kits) induced COX-2 (show COX2 ELISA Kits) expression, promoter activity, and increased the production of prostaglandin E2.
These findings suggest that nuclear factor kappa B(NF-kappaB (show NFKB1 ELISA Kits)) and cyclooxygenase-2 play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin.
COX2 expression is upregulated in CAVD, and its activity contributes to osteogenic gene induction and valve calcification in vitro and in vivo.
These results suggest that COX-2 plays a role in the pathogenesis of Mycoplasma hyopneumoniae -infection.
Brain death increases the expression of COX-1 (show COX1 ELISA Kits) and COX-2 mRNA in the renal medulla
COX-2 is differentially expressed in normal versus lungworm-infected lungs of pigs and is likely to be involved in the pathogenesis of porcine parasitic bronchopneumonia.
In porcine vas (show AVP ELISA Kits) deferens epithelial cell monolayers, increases in anion secretion were associated with preferential upregulation of PTGS2 at the mRNA and protein levels.
expression appears to be positively and negatively regulated by p38 MAPK (show MAPK14 ELISA Kits) and JNK (show MAPK8 ELISA Kits) pathways; alternatively, ERK1/2 (show MAPK1/3 ELISA Kits) appear to be involved in COX-2-independent reparative events that remain to be defined
Neutrophils augment recovery of transepithelial electrical resistance in ischemia-injured ileal mucosa via IL-1beta (show IL1B ELISA Kits)-dependent upregulation of COX-2. (Cyclooxygenase 2)
Administration of estrogen early in pregnancy alters endometrial prostaglandin-endoperoxide synthase 2 (PTGS2) mRNA and protein expression, which may disrupt pregnancy causing total embryonic loss during implantation in the pig.
The effect of EGF (show EGF ELISA Kits) on pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha (show TNF ELISA Kits)) and cyclooxygenase-2 (COX-2), levels during wound healing in swine is reported.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta (show IL1B ELISA Kits),COX-2 (show COX2 ELISA Kits), and TGFbeta1 (show TGFB1 ELISA Kits)
The result demonstrate that mechanical stress on synovial cells induces gene expressions of COX-2 (show COX2 ELISA Kits).
Diabetes enhances the vasodilator response of the rabbit carotid artery to testosterone by a mechanism that includes an increased modulatory activity of the endothelial nitric oxide and an augmented release of COX-2 (show COX2 ELISA Kits) vasodilator, prostacyclin.
Local induction of COX-2 (show COX2 ELISA Kits) during atherosclerosis decreased the sensitivity to norepinephrine and that COX-2 (show COX2 ELISA Kits) inhibitors may increase vascular reactivity at sites of atherosclerotic lesions.
The vesicular gland of castrated goats showed significantly lower AR and COX-2 (show COX2 ELISA Kits) immuno-expression than intact goats indicating that both AR and COX-2 (show COX2 ELISA Kits) are androgen dependent.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
, cyclooxygenase 2
, prostaglandin G/H synthase 2
, prostaglandin G/H synthase and cyclooxygenase
, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
, prostaglandin G/H synthase 2-like
, PGH synthase 2
, PHS II
, glucocorticoid-regulated inflammatory cyclooxygenase
, macrophage activation-associated marker protein P71/73
, prostaglandin H2 synthase 2
, cyclooxygenase 2b
, prostaglandin G/H synthase-2
, cyclooxygenase, prostaglandin endoperoxide H synthase-2
, prostaglandin H synthase-2
, cyclooxygenase type 2
, mitogen-inducible PGHS