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SCD1 (show SCD ELISA Kits) ablation/inhibition decreased cardiac lipid content.
Our data provide evidence that SCD1 (show SCD ELISA Kits) has a broad impact on WAT lipid handling by altering TAG composition in a depot-specific manner, reducing FA reesterification, and regulating markers of lipolysis and glyceroneogenesis.
SCD (show SCD ELISA Kits) expressed by HSCs promoted liver tumor development in mice.
investigated the effect of genetic ablation of SCD1 (show SCD ELISA Kits) in 3T3-L1 adipocytes on membrane microdomain lipid composition at the species-specific level
Splenic effector T cells (CD4 (show CD4 ELISA Kits)(+)CD25 (show IL2RA ELISA Kits)(-)) from age- and sex-matched wild-type (WT) and Scd1KO mice were isolated by FACS and intraperitoneally administered to Rag1KO mice, which were monitored for the development of colitis. At day 60 postcell transfer, Rag1KO mice that received Scd1KO CD4 (show CD4 ELISA Kits)(+)CD25 (show IL2RA ELISA Kits)(-) T cells displayed accelerated and exacerbated colitis than mice receiving WT CD4 (show CD4 ELISA Kits)(+)CD25 (show IL2RA ELISA Kits)(-) T cells.
Scd1 (show SCD ELISA Kits) protects cells against lipotoxicity-mediated apoptosis in proximal tubular cells.
Scd1 (show SCD ELISA Kits) Is Regulated by Dbc1 (show DBC1 ELISA Kits) and SirT1 (show SIRT1 ELISA Kits).
Study provides new insights into the critical role of SCD1 (show SCD ELISA Kits) as a regulator of adipocyte function and lipid metabolism.
The study reports report the 3.25-A crystal structure of human SCD1 (show SCD ELISA Kits) in complex with its substrate, stearoyl-coenzyme A, which defines the new SCD1 (show SCD ELISA Kits) dimetal catalytic center and reveals the determinants of substrate binding.
SCD1 (show SCD ELISA Kits) is a novel oncogenic factor specifically required for tumor cell viability in anaplastic thyroid carcinoma.
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
acyl-CoA desaturase 1
, delta(9)-desaturase 1
, delta-9 desaturase 1
, fatty acid desaturase 1
, stearoyl-CoA desaturase 1