53BP1 (amino terminus) (Human) antibody

Overview

Antigen	53BP1 (amino terminus)
Immunogen	Synthetic peptide corresponding to the amino-terminus of h53BP1, conjugated to a carrier protein.
Reactivity	Human
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG »Matching secondary antibodies
Description	P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Host	Rabbit

Application	Western Blotting (WB)
Application Notes	WB: 1:500
Concentration	0.5 mg/ml
Purity	Affinity purified with antigen.
Buffer	Phosphate-buffered saline, pH 7.2, no preservative added.
Storage	For long term storage, please keep at -70 C or below. Avoid repeared freeze-thaw cycles.
Restrictions	For research use only

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