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Antigen
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ARP1 actin-related protein 1 homolog B, centractin beta (yeast) (ACTR1B)
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Gene ID
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10120
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Immunogen
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ACTR1B (NP_005726, 191 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence: (without GST) SRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPD GSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHK*
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Reactivity
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Human
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Antibody Type
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Monoclonal
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Isotype
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IgG2a Kappa »Matching secondary antibodies
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Description
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ARP1 actin-related protein 1 homolog B, centractin beta (yeast) This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex. Mouse monoclonal antibody raised against a partial recombinant ACTR1B. Synonyms: ARP1B, CTRN2
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Clone
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40000000000
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Host
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Mouse
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