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Product details for D type cyclin (encoded by KSV) antibody
D type cyclin (encoded by KSV) antibody
Overview
| Antigen: | D type cyclin (encoded by KSV) |
| Antibody Type: | Monoclonal |
| Application: | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB) |
| Host: | Rat |
| Quantity: | |
| Price: | 291,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN145114 |
| Availability: | 7 to 10 days until shipment |
Additional Information: D type cyclin (encoded by KSV) antibody
| Antigen | D type cyclin (encoded by KSV) |
| Immunogen | Recombinant fusion protein produced from a clone from KSV. |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported. |
| Clone | 94B |
| Host | Rat |
Application Details: D type cyclin (encoded by KSV) antibody
| Application | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | Protein A purified |
| Buffer | Preservative: NoneConstituents: PBS |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
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