DEDD2 antibody

Overview

Antigen	DEDD2
Antibody Type	Polyclonal
Format	Liquid
Description	A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway.
Host	Rabbit
Specificity	Reacts with residues 144-129 of the DEDD2 protein.

Application	ELISA, Western Blotting (WB)
Application Notes	Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Purity	Serum
Buffer	100 ul serum containing 0.02% sodium azide.
Storage	Maintain at +2-8 C for 3 months or at -20 C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
Restrictions	For research use only

Google Scholar	Find more references for antigen DEDD2 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen DEDD2 (Bioinformatic Harvester (EMBL))