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Product details for Doppel antibody
Doppel antibody
Overview
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| Antigen: | Doppel |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 249,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN110271 |
| Availability: | 1 to 7 days before shipment |
Additional Information: Doppel antibody
| Antigen | Doppel |
| Immunogen | Human doppel protein amino acids |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Description | Doppel is a homolog of the cellular prion protein. Like prion protein, doppel has two N-linked oligosaccharides, and is presented on the cell surface via a glycosylphosphatidylinositol anchor. Unlike prion protein, it lacks the conformationally plastic and octapeptide repeat domains. The primary physiological role of doppel protein remains to be determined, but there is some evidence suggesting that cell surface prion protein can antagonize the toxic effect of doppel expressed in the central nervous system. In addition, the protein may play a major role in human male fertility, given its expression on both sertoli cells and spermatozoa. Cayman Chemical's doppel polyclonal antibody can be used for western blot and immunohistochemistry (formalin-fixed paraffin-embedded sections) analysis on samples of human, murine, or rat origin. The antibody recognizes the nonglycosylated and glycosylated forms of the protein. |
| Host | Rabbit |
| Specificity | Human Doppel protein: +, Murine Doppel protein: +, Rat Doppel protein: + |
Application Details: Doppel antibody
| Application | Western Blotting (WB) |
| Buffer | 200 µg affinity-purified IgG in 400 µl TBS, pH 7.4, containing 50% glycerol, 0.1% BSA, and 0.02% sodium azide |
| Storage | 2 years |
| Restrictions | For Research only |
External Information: Doppel antibody
| Google Scholar | Find more references for antigen Doppel on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Doppel (Bioinformatic Harvester (EMBL)) |
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