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Product details for Estrogen Related Receptor gamma (Human) antibody
Estrogen Related Receptor gamma (Human) antibody
Overview
| Antigen: | Estrogen Related Receptor gamma |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Reactivity: | Human |
| Host: | Rabbit |
| Quantity: | |
| Price: | 302,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN147518 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Estrogen Related Receptor gamma (Human) antibody
| Antigen | Estrogen Related Receptor gamma |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) |
| Reactivity | Human |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | Estrogen related receptor (ERR gamma), a NR3 Steroid Receptor, has been suggested to affect differentiation of the brain, heart, and kidney. ERR gamma binds as a monomer to an extended half-site of the ERRE type (TCAAGGTCA). ERR gamma has been shown to interact with PGC-1 alpha and has been implicated in the regulation of mitochondrial energy metabolism. In humans, ERR gamma pre-mRNA undergoes extensive alternative splicing at the 5 prime end, yielding at least six mRNA splice variants and two protein isoforms that differ by 23 amino acids in the N terminus. ERR gamma has been shown to be overexpressed in breast tumors, and its expression is correlated with levels of ErbB4, a likely indicator of preferred clinical course. As a result, ERR gamma has been suggested to be a potential biomarker for favorable clinical course and, possibly, hormonal sensitivity, and as a candidate target for therapeutic development. |
| Host | Rabbit |
Application Details: Estrogen Related Receptor gamma (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | IHC-P: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 0.01% Sodium AzideConstituents: PBS. pH 7.7 |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
External Information: Estrogen Related Receptor gamma (Human) antibody
| Google Scholar | Find more references for antigen Estrogen Related Receptor gamma on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Estrogen Related Receptor gamma (Bioinformatic Harvester (EMBL)) |
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